Zobrazeno 1 - 10
of 134
pro vyhledávání: '"Jack Satsangi"'
Autor:
Jie Chen, Xixian Ruan, Shuai Yuan, Minzi Deng, Han Zhang, Jing Sun, Lili Yu, Jack Satsangi, Susanna C. Larsson, Evropi Therdoratou, Xiaoyan Wang, Xue Li
Publikováno v:
Chen, J, Ruan, X, Yuan, S, Deng, M, Zhang, H, Sun, J, Yu, L, Satsangi, J, Larsson, S C, Theodoratou, E, Wang, X & Li, X 2023, ' Antioxidants, Minerals, and Vitamins in Relation to Crohn’s disease and Ulcerative Colitis : A Mendelian Randomization Study ', Alimentary Pharmacology and Therapeutics, vol. 57, no. 4, pp. 399-408 . https://doi.org/10.1111/apt.17392
Background: Evidence for antioxidants, minerals and vitamins in relation to the risk of Crohn's disease (CD) and ulcerative colitis (UC) is limited and inconsistent. This mendelian randomization (MR) study aimed to examine the causal associations of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9580bb13992859e9208326bdc322ec3e
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-502275
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-502275
Autor:
Yuhao Sun, Shuai Yuan, Xuejie Chen, Jing Sun, Rahul Kalla, Lili Yu, Lijuan Wang, Xuan Zhou, Xiangxing Kong, Therese Hesketh, Gwo-tzer Ho, Kefeng Ding, Malcolm Dunlop, Susanna C. Larsson, Jack Satsangi, Jie Chen, Xiaoyan Wang, Xue Li, Evropi Theodoratou, Edward L Giovannucci
Publikováno v:
Sun, Y, Yuan, S, Chen, X, Sun, J, Kalla, R, Yu, L, Wang, L, Zhou, X, Kong, X, Hesketh, T, Ho, G-T, Ding, K, Dunlop, M G, Larsson, S C, Satsangi, J, Chen, J, Wang, X, Li, X, Theodoratou, E & Giovannucci, E L 2023, ' The contribution of genetic risk and lifestyle factors in the development of adult-onset inflammatory bowel disease : a prospective cohort study ', The American Journal of Gastroenterology, vol. 118, no. 3, pp. 511-522 . https://doi.org/10.14309/ajg.0000000000002180
SummaryObjectiveThere are few prospective data exploring the combined effect of genetic and lifestyle factors on the incidence of inflammatory bowel disease (IBD), and whether genetic risk of IBD may be mitigated by lifestyle remains unclear.DesignWe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89327c84039adfbb5e0337640fccd465
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-507039
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-507039
Publikováno v:
Current Opinion in Pharmacology
Treatment strategies for inflammatory bowel disease (IBD) now increasingly target deep remission, yet the resultant more aggressive use of medical therapy is associated with potentially serious adverse events and significant costs. It is, therefore,
Autor:
Jan K, Nowak, Alex T, Adams, Rahul, Kalla, Jonas C, Lindstrøm, Simen, Vatn, Daniel, Bergemalm, Åsa V, Keita, Fernando, Gomollón, Jørgen, Jahnsen, Morten H, Vatn, Petr, Ricanek, Jerzy, Ostrowski, Jaroslaw, Walkowiak, Jonas, Halfvarson, Jack, Satsangi, Panpan, You
AIM: To assess the pathobiological and translational importance of whole blood transcriptomic analysis in inflammatory bowel disease (IBD). METHODS: We analyzed whole blood expression profiles from paired-end sequencing in a discovery cohort of 590 E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a36630375db0caedd41703a4d427b428
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-184848
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-184848
Autor:
Simen Svendsen Vatn, Jonas Christoffer Lindstrøm, Aina EF Moen, Stephan Brackmann, Tone M Tannæs, Christine Olbjørn, Daniel Bergemalm, Åsa V Keita, Fernando Gomollon, Trond Espen Detlie, Torben Lüders, Rahul Kalla, Alex Adams, Jack Satsangi, Jørgen Jahnsen, Morten H Vatn, Jonas Halfvarson, Petr Ricanek, Hilde Nilsen
Publikováno v:
Clinical and Experimental Gastroenterology
Simen Svendsen Vatn,1,2,* Jonas Christoffer Lindstrøm,3,4,* Aina EF Moen,1,4,5 Stephan Brackmann,1,2 Tone M Tannæs,1,5 Christine Olbjørn,1,6 Daniel Bergemalm,7 Åsa V Keita,8 Fernando Gomollon,9 Trond Espen Detlie,1,2 Torben Lüders,5 Rahul Kalla,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21032e270e460163b2d80ed103c51e33
http://hdl.handle.net/10852/99143
http://hdl.handle.net/10852/99143
Autor:
Fernando Gomollón, Petr Ricanek, Gwo-Tzer Ho, Nicholas A. Kennedy, Simen Vatn, Nicholas T. Ventham, S McTaggart, Rahul Kalla, Daniel Bergemalm, Jan Krzysztof Nowak, C Clarke, B Lopez-Jimena, Alasdair Ivens, Jørgen Jahnsen, Morten H. Vatn, Jack Satsangi, Amy H. Buck, Johan D. Söderholm, Ruby White, Alex Adams, Jonas Halfvarson
Publikováno v:
Zaguán: Repositorio Digital de la Universidad de Zaragoza
Universidad de Zaragoza
Zaguán. Repositorio Digital de la Universidad de Zaragoza
instname
2020, ' Whole blood profiling of T-cell derived miRNA allows the development of prognostic models in inflammatory bowel disease ', Journal of Crohn's and Colitis, vol. 14, no. 12, pp. 1724–1733 . https://doi.org/10.1093/ecco-jcc/jjaa134
Universidad de Zaragoza
Zaguán. Repositorio Digital de la Universidad de Zaragoza
instname
2020, ' Whole blood profiling of T-cell derived miRNA allows the development of prognostic models in inflammatory bowel disease ', Journal of Crohn's and Colitis, vol. 14, no. 12, pp. 1724–1733 . https://doi.org/10.1093/ecco-jcc/jjaa134
Background MicroRNAs [miRNAs] are cell-specific small non-coding RNAs that can regulate gene expression and have been implicated in inflammatory bowel disease [IBD] pathogenesis. Here we define the cell-specific miRNA profiles and investigate its bio
Autor:
Philip Jenkinson, Mrithula Shivakumar, Gareth-Rhys Jones, Ian D. Arnott, R Grant, Jack Satsangi, Charlie W. Lees, Ruairi Lynch, Nikolas Plevris, F Jagger, William M Brindle, Thomas Manship
Publikováno v:
Inflammatory Bowel Diseases. 27:451-457
Background Intravenous (IV) steroids remain the first-line treatment for patients with acute ulcerative colitis (UC). However, 30% of patients do not respond to steroids, requiring second-line therapy and/or surgery. There are no existing indices tha
Publikováno v:
Journal of Crohn's & Colitis
Acute severe ulcerative colitis [ASUC] remains a common medical emergency, with 25% of patients with ulcerative colitis experiencing at least one event in their disease course. Despite advances in medical therapy, ASUC continues to be associated with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dd6f2c0d7b4edff58e4b7a4ab8df9e7
https://ora.ox.ac.uk/objects/uuid:3ee94d23-ac44-446b-8bbf-e38a4c5e534f
https://ora.ox.ac.uk/objects/uuid:3ee94d23-ac44-446b-8bbf-e38a4c5e534f
Autor:
Vineet Ahuja, Bruce George, Alex Adams, D Subhaharan, Tim Ambrose, Sudheer K. Vuyyuru, W Mohsen, Pradeep Kakkadasam Ramaswamy, Vipin Gupta, Thomas P. Chapman, Colleen Gc McGregor, Oliver Brain, Saurabh Kedia, Alissa Walsh, Jack Satsangi, Rebecca Palmer, Simon Travis
Background & aimsWe aimed to determine whether changes in ulcerative colitis management have translated to improved outcomes, in order to develop a simple model to predict steroid non-response on admission.MethodsOutcomes of 131 adult ASC admissions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3585ec6f53363d49310fd3324f5937b
https://doi.org/10.1101/2021.07.14.21260477
https://doi.org/10.1101/2021.07.14.21260477
Background and aimsThe IBD-Character consortium has recruited large internationally based inception cohorts of treatment-naïve inflammatory bowel disease (IBD) patients, providing a unique resource to derive a simple transcriptome signature in the f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a18a9c65aa781be9d9306b77b546e391
https://doi.org/10.1101/2021.07.09.21259804
https://doi.org/10.1101/2021.07.09.21259804