Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Nodi Dehvari"'
Autor:
Emanuela Talamonti, Jelena Davegardh, Anastasia Kalinovich, Sten M.M. van Beek, Nodi Dehvari, Carina Halleskog, Hamza M. Bokhari, Dana S. Hutchinson, Seungmin Ham, Laura J. Humphrys, Nicola C. Dijon, Aikaterini Motso, Anna Sandstrom, Evelyn Zacharewicz, Ilga Mutule, Edgars Suna, Jana Spura, Karolina Ditrychova, Leigh A. Stoddart, Nicholas D. Holliday, Shane C. Wright, Volker M. Lauschke, Soren Nielsen, Camilla Scheele, Elizabeth Cheesman, Joris Hoeks, Peter Molenaar, Roger J. Summers, Benjamin Pelcman, Gopala K. Yakala, Tore Bengtsson
Publikováno v:
Molecular Metabolism, Vol 85, Iss , Pp 101931- (2024)
Objective: Simultaneous activation of β2- and β3-adrenoceptors (ARs) improves whole-body metabolism via beneficial effects in skeletal muscle and brown adipose tissue (BAT). Nevertheless, high-efficacy agonists simultaneously targeting these recept
Externí odkaz:
https://doaj.org/article/3d4a3a5490234ea7a397025d54414624
Autor:
Claes-Göran Östenson, Joris Hoeks, Tore Bengtsson, Anastasia V. Kalinovich, Carina Halleskog, Nodi Dehvari, Jessica M. Olsen, Alice Åslund, Gert Schaart, Elisabete Forsberg, Anna L. Sandström, Evelyn Zacharewicz, Sten M M van Beek, Roger Berlin, Mia Rinde
Publikováno v:
Diabetologia
Diabetologia, 63(8), 1603-1615. Springer, Cham
Diabetologia, 63(8), 1603-1615. Springer, Cham
Aims/hypothesis Chronic stimulation of β2-adrenoceptors, opposite to acute treatment, was reported to reduce blood glucose levels, as well as to improve glucose and insulin tolerance in rodent models of diabetes by essentially unknown mechanisms. We
Autor:
Michelle L. Halls, Anna L. Sandström, Dana S. Hutchinson, Masaaki Sato, Nodi Dehvari, Jon Merlin, Robert I. Csikasz, Roger J. Summers, Anette I. Öberg, Saori Mukaida, Jessica M. Olsen, Tore Bengtsson, Bronwyn A Evans, Martina Kocan
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 316:R666-R677
The type 2 diabetes epidemic makes it important to find insulin-independent ways to improve glucose homeostasis. This study examines the mechanisms activated by a dual β2-/β3-adrenoceptor agonist, BRL37344, to increase glucose uptake in skeletal mu
Publikováno v:
British Journal of Pharmacology. 175:4072-4082
The β3 -adrenoceptor was initially an attractive target for several pharmaceutical companies due to its high expression in rodent adipose tissue, where its activation resulted in decreased adiposity and improved metabolic outputs (such as glucose ha
Autor:
Olof S. Dallner, Tore Bengtsson, Nodi Dehvari, Roger J. Summers, Robert I. Csikasz, Dana S. Hutchinson, Masaaki Sato, Anna L. Sandström, Jessica M. Olsen, Anette I. Öberg
Publikováno v:
Diabetes. 63(12)
There is an increasing worldwide epidemic of type 2 diabetes that poses major health problems. We have identified a novel physiological system that increases glucose uptake in skeletal muscle but not in white adipocytes. Activation of this system imp
Autor:
Mona Wilcke, Claes-Göran Östenson, Robert I. Csikasz, Nodi Dehvari, Anette I. Öberg, Dana S. Hutchinson, Tore Bengtsson, Kamal Yassin, Irina G. Shabalina
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22510 (2011)
PLoS ONE
PLoS ONE
BACKGROUND: There is considerable interest in identifying compounds that can improve glucose homeostasis. Skeletal muscle, due to its large mass, is the principal organ for glucose disposal in the body and we have investigated here if shikonin, a nap