Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Francisco D. Morón-Duran"'
Autor:
Albert Tauler, Sara C. Kozma, George Thomas, Francisco D. Morón-Duran, Carmen Morcelle, Antonio Gentilella, Sandra Menoyo
Publikováno v:
Cancer research. 79(17)
The role of MYC in regulating p53 stability as a function of increased ribosome biogenesis is controversial. On the one hand, it was suggested that MYC drives the overexpression of ribosomal proteins (RP)L5 and RPL11, which bind and inhibit HDM2, sta
Autor:
George Thomas, Pedro Fuentes, Sara C. Kozma, Antonio Gentilella, Julio Castaño, Clara Bueno, Gemma Turón, Marta Ruiz, Francisco D. Morón-Duran, Joffrey Pelletier, Pablo Menendez, Ferran Riaño-Canalias, Guilherme Zweig-Rocha, Albert Tauler
Publikováno v:
Molecular Cell. 67:55-70.e4
Ribosomal protein (RP) expression in higher eukaryotes is regulated translationally through the 5′TOP sequence. This mechanism evolved to more rapidly produce RPs on demand in different tissues. Here we show that 40S ribosomes, in a complex with th