Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Yong J. Lee"'
Autor:
Yong Seok Park, Kalishwaralal Kalimuthu, Yong J. Lee, Ja Lok Ku, Jin Hong Kim, Xu Luo, Lin Zhang, M. Haroon A. Choudry
Publikováno v:
Journal of Cellular Physiology. 236:6666-6677
Abnormalities of the tumor vasculature result in insufficient blood supply and development of a tumor microenvironment that is characterized by low glucose concentrations, low extracellular pH, and low oxygen tensions. We previously reported that glu
Autor:
Lisa Bailey, David L. Bartlett, Xinxin Song, Se Hoon Hong, William T. Kwon, Yong J. Lee, Yong Tae Kwon, Per H. Basse
Publikováno v:
Molecular Cancer Therapeutics. 15:1591-1601
Since its discovery in 1995, TNF-related apoptosis-inducing ligand (TRAIL) has sparked growing interest among oncologists due to its remarkable ability to induce apoptosis in malignant human cells, but not in most normal cells. However, one major dra
Ferroptosis-inducing agents enhance TRAIL-induced apoptosis through upregulation of death receptor 5
Autor:
Dae Hee Lee, Jian Yu, David L. Bartlett, Yong Seok Park, Haroon A. Choudry, Yong J. Lee, Seong Hye Park, So Yeon Jeong, Young Sun Lee, Sang Cheul Oh
Publikováno v:
Journal of cellular biochemistry. 120(1)
Ferroptosis is considered genetically and biochemically distinct from other forms of cell death. In this study, we examined whether ferroptosis shares cell death pathways with other types of cell death. When human colon cancer HCT116, CX-1, and LS174
Autor:
Yong J. Lee, Dae Hee Lee, Haroon A. Choudry, Min Jee Jo, David L. Bartlett, Young Sun Lee, William T. Kwon, Yoon A. Jeong, Se Hoon Hong
Publikováno v:
Oncotarget
Ferroptosis is a type of programmed cell death that depends on iron and is characterized by the accumulation of lipid peroxides. In the present study, we investigated the nature of the interplay between ferroptosis and other forms of cell death such
Autor:
Yong J. Lee
Publikováno v:
Cancer Research. 79:707-707
Introduction: Several processes lead to cell death; ferroptosis, apoptosis, necrosis, and autophagy are the primary mechanisms. Each type of biological death has been believed to have a distinct biochemical and morphological fingerprint. However, eme
Autor:
Dae Hee Lee, Yong J. Lee, Se Hoon Hong, Yoo A. Jeong, Min J. Jo, Young Sun Lee, David L. Bartlett, William T. Kwon, Haroon A. Choudry
Publikováno v:
Cancer Research. 78:2321-2321
Ferroptosis is a type of programmed cell death that depends on iron and is characterized by the accumulation of lipid peroxides. In the present study, we investigated the nature of the interplay between ferroptosis and other forms of cell death such
Autor:
Marco A. Alcala, Jinsang Yoo, David L. Bartlett, Byeong-Chel Lee, Bae-Hang Park, Dae Hee Lee, Kyung Soo Park, Yong J. Lee
Publikováno v:
Journal of Cellular Biochemistry. 110:1073-1081
Approximately 25% of patients with colorectal cancer develop metastases to the liver, and surgery is currently the best treatment available. But there are several patients who are unresectable, and isolated hepatic perfusion (IHP) offers a different
Publikováno v:
Journal of Cellular Biochemistry. 104:1172-1180
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a member of the TNF superfamily. TRAIL shows strong cytotoxicity to many cancer cells but minimal cytotoxicity to most normal cells. Interestingly, our recent studies have demonstrate
Autor:
Yong J. Lee, Jinsang Yoo
Publikováno v:
Molecular Pharmacology. 72:1586-1592
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a promising cancer therapeutic agent because of its tumor selectivity. TRAIL is known to induce apoptosis in cancer cells but spare most normal cells. In this study, we examined wheth
Publikováno v:
Journal of Biological Chemistry. 282:319-328
Previous studies have shown that repeated application of TRAIL induces acquired resistance to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL). Using human prostate adenocarcinoma DU-145 and human pancreatic carcinoma MiaPaCa-2 cells a