Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Xiangliang Yuan"'
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/a7810022b49b4131bcd0dbc371abc1d1
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The immunosuppressive status of the tumor microenvironment (TME) remains poorly defined due to a lack of understanding regarding the function of tumor-associated macrophages (TAMs), which are abundant in the TME. TAMs are crucial drivers of tumor pro
Externí odkaz:
https://doaj.org/article/b663f072f50e43ee89a75025089a4a6e
Autor:
Yuhan, Wei, Jianwei, Zhang, Xueke, Fan, Zhi, Zheng, Xiaoyue, Jiang, Dexi, Chen, Yuting, Lu, Yingrui, Li, Miao, Wang, Min, Hu, Qi, Du, Liuting, Yang, Hongzhong, Li, Yi, Xiao, Yongfu, Li, Jiangtao, Jin, Deying, Wang, Xiangliang, Yuan, Qin, Li
Publikováno v:
Frontiers in Immunology. 13
The profiling of the tumor immune microenvironment (TIME) is critical for guiding immunotherapy strategies. However, how the composition of the immune landscape affects the tumor progression of gastric cancer (GC) is ill-defined. Here, we used mass c
Autor:
Lei Zhang, Li Jiang, Liang Yu, Qin Li, Xiangjun Tian, Jingquan He, Ling Zeng, Yuqin Yang, Chaoran Wang, Yuhan Wei, Xiaoyue Jiang, Jing Li, Xiaolu Ge, Qisheng Gu, Jikun Li, Di Wu, Anthony J. Sadler, Di Yu, Dakang Xu, Yue Gao, Xiangliang Yuan, Baokun He
Publikováno v:
Nature communications. 13(1)
Anti-cancer immunity and response to immune therapy is influenced by the metabolic states of the tumours. Immune checkpoint blockade therapy (ICB) is known to involve metabolic adaptation, however, the mechanism is not fully known. Here we show, by m
Autor:
J. Jack Lee, Xuedong Yin, Cassian Yee, Wenling Kuo, Hongzhong Li, Yuan Zhang, Yi Xiao, Li Qin, Huihui Fan, Guosheng Ren, Don L. Gibbons, Hideo Yagita, Da Pang, Yohei Saito, Dihua Yu, Ping Li, Jun Yao, Angela Halpin, Zhongming Zhao, Xiangliang Yuan
Publikováno v:
Cancer Cell
Summary Reinvigoration of antitumor immunity remains an unmet challenge. Our retrospective analyses revealed that cancer patients who took antihistamines during immunotherapy treatment had significantly improved survival. We uncovered that histamine
Lipid accumulation in macrophages confers protumorigenic polarization and immunity in gastric cancer
Autor:
Peng Zhang, Yi Liu, Lei Chen, Li Jiang, Qin Luo, Naisheng Zheng, Guohua Xie, Weiwei Wang, Lisong Shen, Peiming Zheng, Ping Dong, Dongdong Li, Tingting Wang, Xiangliang Yuan
Publikováno v:
Cancer Science
Heterotypic interactions between tumor cells and macrophages can enable tumor progression and hold potential for the development of therapeutic interventions. However, the communication between tumors and macrophages and its mechanism are poorly unde
Autor:
Da Pang, Xuedong Yin, Don L. Gibbons, Angela Halpin, Yohei Saito, Cassian Yee, Yuan Zhang, J. Jack Lee, Hongzhong Li, Ping Li, Hideo Yagita, Xiangliang Yuan, Jun Yao, Dihua Yu, Yi Xiao, Guosheng Ren
Publikováno v:
SSRN Electronic Journal.
How to revive anti-tumor immunity in cancer patients is an unmet challenge. In retrospective screening of common medications that may affect immunotherapy response in patients, we found that patients who took antihistamines during immunotherapy treat
Autor:
Lisong Shen, Junhua Li, Peiming Zheng, Guohua Xie, Ping Dong, Yanhui Ma, Lei Chen, Li Jiang, Ping Wang, Hui Chen, Tingting Wang, Weiwei Wang, Xiangliang Yuan, Qin Luo, Yi Liu, Peng Zhang
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 9, Iss 4, Pp 1-14 (2018)
Cell Death and Disease, Vol 9, Iss 4, Pp 1-14 (2018)
Tumor-associated macrophages (TAMs) are a major component of the tumor microenvironment and have been shown to contribute to tumor aggressiveness. However, the detailed mechanisms underlying the pro-metastatic effect of TAMs on gastric cancer are not
Publikováno v:
Cancer Research. 78:59-59
14-3-3ζ overexpression in breast cancer is associated with accelerated cancer progression and poor clinical outcome in patients. Our previous study revealed that 14-3-3ζ overexpression promotes epithelial mesenchymal transition (EMT) of breast canc
Autor:
Tong tong Zhang, Jian Wang, Feng Min Zhang, Mei Xing Li, Lei Chen, Xiangliang Yuan, Hai Liang Ge, Dakang Xu, Ping Dong, Xing an Wang, Jian Xue, Li Song Shen
Publikováno v:
Clinical Immunology. 134:277-288
The transcription factor Foxp3 plays a key role in CD4(+)CD25(+) regulatory T (Treg) cell function. A correlation has been shown between survival and the frequency of tumor-infiltrating Foxp3-positive Treg cells in cancer patients. However, few studi