Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Yong J. Lee"'
Autor:
Jae J. Song, Yong J. Lee
Publikováno v:
Cellular Signalling. 20:892-906
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) has been shown to induce apoptosis through caspase activation in a number of cancer cell lines while displaying minimal or no toxicity on normal cells, suggesting that this protein may h
Publikováno v:
Cell Death & Differentiation. 9:448-456
We previously reported that overexpression of HSP25 delayed cell growth, increased the level of p21(waf), reduced the levels of cyclin D1, cyclin A and cdc2, and induced radioresistance in L929 cells. In this study, we demonstrated that HSP25 induced
Publikováno v:
The American Journal of Pathology. 160:1069-1075
We investigated the role of galectin-3 in metastasis of human breast carcinoma BT549 cells using the experimental liver metastasis model. Underlying mechanisms were then elucidated using the liver/tumor co-culture and cell culture systems. After intr
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 51:785-790
Purpose: Combined use of 13- cis -retinoic acid (cRA) and interferon-α2a (IFNα) induced significant radiosensitization in human cervical cancer ME-180 cell line, whereas it failed to achieve similar radiation enhancement in HeLa cells. The differen
Publikováno v:
Cell Death & Differentiation. 8:44-50
Cyclin D1 expression is co-regulated by growth factor and cell adhesion signaling. Cell adhesion to the extracellular matrix activates focal adhesion kinase (FAK), which is essential for cyclin D1 expression. Upon the loss of cell adhesion, cyclin D1
Autor:
Mi Young Han, Sun Hee Baek, Eun Mi Park, Young Mee Park, Jin Na Min, Yong J. Lee, Yun Sil Lee
Publikováno v:
Journal of Cellular Physiology. 183:100-107
Expression of heat shock proteins (HSPs) has been shown to protect mammalian cells exposed to a variety of stress stimuli. Among various HSPs, small HSPs from diverse species were shown to protect cells against oxidative stress. Here, we show that th
Autor:
Sandra Galoforo, Yong J. Lee, Lisa A. Ridnour, Julia E. Sim, Henry Jay Forman, Peter M. Corry, Douglas R. Spitz, Jinah Choi
Publikováno v:
Free Radical Biology and Medicine. 28:575-584
Signal transduction pathway involved in glucose deprivation-induced oxidative stress were investigated in human breast carcinoma cells (MCF-7/ADR). In MCF-7/ADR, glucose deprivation-induced prolonged activation of c-Jun N-terminal kinase (JNK1) as we
Publikováno v:
International Journal of Developmental Neuroscience. 17:447-461
To investigate the hypothesis that protein kinase Calpha (PKCalpha) is functional glial tumor cell invasion, stable PKCalpha sense and antisense transfected U-87 cell lines were established and PKCalpha expression characterized by Western blot and PK
Autor:
Sandra Galoforo, Yong J. Lee, Robert V. Blackburn, M B S Christine Berns, Peter M. Corry, Nalini M. Motwani
Publikováno v:
Cancer. 82:1137-1145
BACKGROUND High grade gliomas represent very aggressive and lethal forms of human cancer, which often exhibit recurrence after surgical intervention and resistance to conventional chemotherapeutic and radiologic treatment. The clinically approved ant
Publikováno v:
Journal of Cellular Physiology. 174:27-34
Previously we and others have demonstrated that oxidative stress involving generation of reactive oxygen species (ROS) is responsible for the cytotoxic action of TNF alpha. Protective effect of small heat shock proteins (HSP) against diverse oxidativ