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pro vyhledávání: '"Hua-Ling Chen"'
Autor:
Chao Yun Yuan, Tzu-Ching Chang, Huei Hsuan Cheng, Shau Ku Huang, Hua Ling Chen, Kenneth K. Wu, Cheng Chin Kuo
Publikováno v:
Journal of Biological Chemistry. 293:11131-11142
5-Methoxytryptophan (5-MTP) is a tryptophan metabolite with recently discovered anti-inflammatory and tumor-suppressing activities. Its synthesis is catalyzed by a hydroxyindole O-methyltransferase (HIOMT)-like enzyme. However, the exact identity of
Publikováno v:
Oncotarget
We reported previously that human fibroblasts release 5-methoxytryptophan (5-MTP) which inhibits cancer cell COX-2 overexpression and suppresses cancer cell migration and metastasis. To determine whether fibroblasts block cancer cell epithelial mesen
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 7, p e69702 (2013)
PLoS ONE, Vol 8, Iss 7, p e69702 (2013)
We hypothesized that prostacyclin (PGI2) protects vascular smooth muscle cell (VSMC) against apoptosis and phenotypic switch through peroxisome proliferator-activated receptor-α (PPARα) activation and 14-3-3 upregulation. Here we showed that transf
Publikováno v:
Journal of biomedical science. 12(2)
Aurora kinases are emerging as key regulators of centrosome function, chromosome segregation and cytokinesis. We previously isolated Aurora-C (Aie1), a third type of Aurora kinase, in a screen for kinases expressed in mouse sperm and eggs. Currently,