Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Khalid M. El-Say"'
Publikováno v:
Pharmaceutics, Vol 13, Iss 739, p 739 (2021)
Pharmaceutics
Volume 13
Issue 5
Pharmaceutics
Volume 13
Issue 5
To avoid the first-pass metabolism of avanafil (AVA) and its altered absorption in the presence of food after oral administration, this study aimed to investigate the potential of TPGS-based mixed micelle (MM)-loaded film for transdermal delivery and
Publikováno v:
International Journal of Nanomedicine
Osama AA Ahmed,1,2 Khalid M El-Say,1,3 Bader M Aljaeid,1 Shaimaa M Badr-Eldin,1,4 Tarek A Ahmed1,3 1Department of Pharmaceutics, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia; 2Department of Pharmaceutics and Industr
Autor:
Hossam S. El-Sawy, Tarek A. Ahmed, Khalid M. El-Say, Magid Abou-Gharbia, Reza Fassihi, Arwa H. Aljefri
Publikováno v:
International Journal of Pharmaceutics. 608:121057
To enhance the poor bioavailability and extensive liver metabolism of atorvastatin calcium (ATC), we have developed an oleic acid–reinforced PEGylated polymethacrylate (OLA–PEG–E-RLPO) transdermal film as a convenient and alternative delivery s
Autor:
Tarek A. Ahmed, Khalid M. El-Say
Publikováno v:
European Journal of Pharmaceutical Sciences. 88:246-256
The goal was to develop an optimized transdermal finasteride (FNS) film loaded with drug microplates (MIC), utilizing two-step optimization, to decrease the dosing schedule and inconsistency in gastrointestinal absorption. First; 3-level factorial de
Publikováno v:
International journal of pharmaceutics. 500(1-2)
This work aimed to develop an optimized ethosomal formulation of glimepiride then loading into transdermal films to offer lower drug side effect, extended release behavior and avoid first pass effect. Four formulation factors were optimized for their
Publikováno v:
Pharmaceutical development and technology. 22(4)
This study aimed at employing Plackett-Burman design in screening formulation variables that affect quality of matrix-type simvastatin (SMV) transdermal film. To achieve this goal, 12 formulations were prepared by casting method. The investigated var
Autor:
Khalid M. El-Say, Shaimaa M Badr-Eldin, Usama A. Fahmy, Hibah M. Aldawsari, Osama A. A. Ahmed, Tarek A. Ahmed
Publikováno v:
Pharmaceutical development and technology. 20(8)
Detailed optimization process was carried out to enhance permeation parameters, and hence bioavailability, of simvastatin (SMV) transdermal films.SMV solubility was investigated in various oils, surfactants and co-surfactants/co-solvents. Mixtures of
Autor:
Osama A. A. Ahmed, Ashraf B. Abdel-Naim, Alaa Khedr, Zainy M. Banjar, Mohsen I. Afouna, Khalid M. El-Say
Publikováno v:
Expert opinion on drug delivery. 11(7)
To optimize and use of glimepiride (GMD)-loaded self-nanoemulsifying delivery systems (SNEDs) for the preparation of transdermal patches.Mixture design was utilized to optimize GMD-loaded SNEDs in acidic and aqueous pH media. Optimized GMD-loaded SNE