Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Lefaudeux, D."'
Autor:
Hoda U; National Heart and Lung Institute, Imperial College London, and Biomedical Research Unit, Royal Brompton and Harefield NHS Trust, London, UK., Pavlidis S; Department of Computing & Data Science Institute, Imperial College London., Bansal AT; Acclarogen, Cambridge, UK., Takahashi K; National Heart and Lung Institute, Imperial College London, and Biomedical Research Unit, Royal Brompton and Harefield NHS Trust, London, UK.; Research Centre for Allergy and Clinical Immunology, Asahi General Hospital, Asahi, Japan., Hu S; Acclarogen, Cambridge, UK., Ng Kee Kwong F; National Heart and Lung Institute, Imperial College London, and Biomedical Research Unit, Royal Brompton and Harefield NHS Trust, London, UK., Rossios C; National Heart and Lung Institute, Imperial College London, and Biomedical Research Unit, Royal Brompton and Harefield NHS Trust, London, UK., Sun K; Acclarogen, Cambridge, UK., Bhavsar P; National Heart and Lung Institute, Imperial College London, and Biomedical Research Unit, Royal Brompton and Harefield NHS Trust, London, UK., Loza M; Janssen Research and Development, High Wycombe, Buckinghamshire, UK., Baribaud F; Janssen Research and Development, High Wycombe, Buckinghamshire, UK., Chanez P; Assistance Publique des Hôpitaux de Marseille, Clinique des Bronches, Allergies et Sommeil, Aix Marseille Université, Marseille, France., Fowler SJ; Division of Infection, Immunity and Respiratory Medicine, Faculty of Biology, School of Biological Sciences, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, and NIHR Biomedical Research Centre, Manchester University Hospitals NHS Foundation Trust, Manchester, UK., Horvath I; Department of Pulmonology, Semmelweis University, Budapest, Hungary., Montuschi P; Catholic University of Sacred Heart, Rome, Italy., Singer F; Department of Respiratory Medicine, University Children's Hospital Zurich and Childhood Research Center, Zurich, and Department of Paediatrics, Inselspital, University of Bern, Switzerland., Musial J; Department of Medicine, Jagiellonian University Medical College, Krakow, Poland., Dahlen B; Centre for Allergy Research, Karolinska Institutet, Stockholm, Sweden., Krug N; Fraunhofer Institute for Toxicology and Experimental Medicine, Hannover, Germany., Sandstrom T; Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden., Shaw DE; Respiratory Research Unit, University of Nottingham, UK., Lutter R; Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands., Fleming LJ; National Heart and Lung Institute, Imperial College London, and Biomedical Research Unit, Royal Brompton and Harefield NHS Trust, London, UK., Howarth PH; NIHR Southampton Biomedical Research Centre, Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, UK., Caruso M; Department of Biochemical and Biotechnological Medicine, University of Catania, Catania, Italy., Sousa AR; Respiratory Therapeutic Unit, GSK, Stockley Park, UK., Corfield J; AstraZeneca R&D, Molndal, Sweden, and Areteva R&D, Nottingham, UK., Auffray C; European Institute for Systems Biology and Medicine, CNRS-ENS-UCBL-INSERM, Lyon, France., De Meulder B; European Institute for Systems Biology and Medicine, CNRS-ENS-UCBL-INSERM, Lyon, France., Lefaudeux D; European Institute for Systems Biology and Medicine, CNRS-ENS-UCBL-INSERM, Lyon, France., Dahlen SE; Centre for Allergy Research, Karolinska Institutet, Stockholm, Sweden., Djukanovic R; NIHR Southampton Biomedical Research Centre, Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, UK., Sterk PJ; Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands., Guo Y; Acclarogen, Cambridge, UK., Adcock IM; National Heart and Lung Institute, Imperial College London, and Biomedical Research Unit, Royal Brompton and Harefield NHS Trust, London, UK., Chung KF; National Heart and Lung Institute, Imperial College London, and Biomedical Research Unit, Royal Brompton and Harefield NHS Trust, London, UK.
Publikováno v:
Clinical and translational medicine [Clin Transl Med] 2022 Apr; Vol. 12 (4), pp. e816.
Autor:
Hekking PP; Respiratory Medicine, Academic Medical Centre, Amsterdam, The Netherlands. Electronic address: p.w.hekking@amc.uva.nl., Loza MJ; Janssen Research and Development, Johnson & Johnson, Spring House, Pa., Pavlidis S; Data Science Institute, Imperial College, London, United Kingdom., de Meulder B; European Institute for Systems Biology and Medicine, Université de Lyon, Lyon, France., Lefaudeux D; European Institute for Systems Biology and Medicine, Université de Lyon, Lyon, France., Baribaud F; Janssen Research and Development, Johnson & Johnson, Spring House, Pa., Auffray C; European Institute for Systems Biology and Medicine, Université de Lyon, Lyon, France., Wagener AH; Respiratory Medicine, Academic Medical Centre, Amsterdam, The Netherlands., Brinkman P Ir; Respiratory Medicine, Academic Medical Centre, Amsterdam, The Netherlands., Lutter R Ir; Respiratory Medicine, Academic Medical Centre, Amsterdam, The Netherlands., Bansal AT; Acclarogen, Cambridge, United Kingdom., Sousa AR; Discovery Medicine, GlaxoSmithKline, Brentford, United Kingdom., Bates SA; Discovery Medicine, GlaxoSmithKline, Brentford, United Kingdom., Pandis Y; Data Science Institute, Imperial College, London, United Kingdom., Fleming LJ; Data Science Institute, Imperial College, London, United Kingdom., Shaw DE; Respiratory Research Unit, University of Nottingham, Nottingham, United Kingdom., Fowler SJ; Centre for Respiratory Medicine and Allergy, Institute of Inflammation and Repair, University of Manchester and University Hospital of South Manchester, Manchester Academic Health Sciences Centre, Manchester, United Kingdom., Guo Y; Data Science Institute, Imperial College, London, United Kingdom., Meiser A; Data Science Institute, Imperial College, London, United Kingdom., Sun K; Data Science Institute, Imperial College, London, United Kingdom., Corfield J; Areteva, Nottingham, United Kingdom., Howarth PH; NIHR Southampton Centre for Biomedical Research, University of Southampton, Southampton, United Kingdom., Bel EH; Respiratory Medicine, Academic Medical Centre, Amsterdam, The Netherlands., Adcock IM; National Heart & Lung Institute, Imperial College, London, United Kingdom., Chung KF; National Heart & Lung Institute, Imperial College, London, United Kingdom., Djukanovic R; NIHR Southampton Centre for Biomedical Research, University of Southampton, Southampton, United Kingdom., Sterk PJ; Respiratory Medicine, Academic Medical Centre, Amsterdam, The Netherlands.
Publikováno v:
The Journal of allergy and clinical immunology [J Allergy Clin Immunol] 2018 Apr; Vol. 141 (4), pp. 1280-1290. Date of Electronic Publication: 2017 Jul 26.
Autor:
Schofield, James P. R., Burg, Dominic, Nicholas, Ben, Strazzeri, Fabio, Brandsma, Joost, Staykova, Doroteya, Folisi, Caterina, Bansal, Aruna T., Xian, Yang, Guo, Yike, Rowe, Anthony, Corfield, Julie, Wilson, Susan, Ward, Jonathan, Lutter, Rene, Shaw, Dominick E., Bakke, Per S., Caruso, Massimo, Dahlen, Sven-Erik, Fowler, Stephen J., Horvath, Ildiko, Howarth, Peter, Krug, Norbert, Montuschi, Paolo, Sanak, Marek, Sandstrom, Thomas, Sun, Kai, Pandis, Ioannis, Riley, John, Auffray, Charles, De Meulder, Bertrand, Lefaudeux, Diane, Sousa, Ana R., Adcock, Ian M., Chung, Kian Fan, Sterk, Peter J., Skipp, Paul J., Djukanovic, Ratko, Ahmed, H., Allen, D., Badorrek, P., Ballereau, S., Baribaud, F., Batuwitage, M. K., Bedding, A., Behndig, A. F., Berglind, A., Berton, A., Bigler, J., Boedigheimer, M. J., Bonnelykke, K., Brinkman, P., Bush, A., Campagna, D., Casaulta, C., Chaiboonchoe, A., Davison, T., De Meulder, B., Delin, I., Dennison, P., Dodson, P., El Hadjam, L., Erzen, D., Faulenbach, C., Fichtner, K., Fitch, N., Formaggio, E., Gahlemann, M., Galffy, G., Garissi, D., Garret, T., Gent, J., Guillmant-Farry, E., Henriksson, E., Hoda, U., Hohlfeld, J. M., Hu, X., James, A., Johnson, K., Jullian, N., Kerry, G., Klueglich, M., Knowles, R., Konradsen, J. R., Kretsos, K., Krueger, L., Lantz, A. -S, Larminie, C., Latzin, P., Lefaudeux, D., Lemonnier, N., Lowe, L. A., Lutter, R., Manta, A., Mazein, A., McEvoy, L., Menzies-Gow, A., Mores, N., Murray, C. S., Nething, K., Nihlen, U., Niven, R., Nordlund, B., Nsubuga, S., Pellet, J., Pison, C., Pratico, G., Puig Valls, M., Riemann, K., Rocha, J. P., Rossios, C., Santini, G., Saqi, M., Scott, S., Sehgal, N., Selby, A., Soderman, P., Sogbesan, A., Spycher, F., Stephan, S., Stokholm, J., Sunther, M., Szentkereszty, M., Tamasi, L., Tariq, K., Valente, S., van Aalderen, W. M., van Drunen, C. M., Van Eyll, J., Vyas, A., Yu, W., Zetterquist, W., Zolkipli, Z., Zwinderman, A. H., Adriaens, Nora, Aliprantis, Antonios, Alving, Kjell, Bakke, Per, Balgoma, David, Barber, Clair, Baribaud, Frederic, Bates, Stewart, Bautmans, An, Beleta, Jorge, Bochenek, Grazyna, Braun, Armin, Carayannopoulos, Leon, Rocha, Joao Pedro Carvalho da Purificacao, Chaleckis, Romanas, D'Amico, Arnaldo, De Alba, Jorge, De Lepeleire, Inge, Dekker, Tamara, Dijkhuis, Annemiek, Draper, Aleksandra, Edwards, Jessica, Emma, Rosalia, Ericsson, Magnus, Flood, Breda, Gallart, Hector, Gomez, Cristina, Gove, Kerry, Gozzard, Neil, Haughney, John, Hewitt, Lorraine, Hohlfeld, Jens, Holweg, Cecile, Hu, Richard, Hu, Sile, Kamphuis, Juliette, Kennington, Erika J., Kerry, Dyson, Knobel, Hugo, Kolmert, Johan, Kots, Maxim, Kuo, Scott, Kupczyk, Maciej, Lambrecht, Bart, Lone-Latif, Saeeda, Loza, Matthew J., Marouzet, Lisa, Martin, Jane, Masefield, Sarah, Mathon, Caroline, Meah, Sally, Meiser, Andrea, Metcalf, Leanne, Mikus, Maria, Miralpeix, Montse, Monk, Philip, Naz, Shama, Nilsson, Peter, Ostling, Jorgen, Pacino, Antonio, Palkonen, Susanna, Pavlidis, Stelios, Pennazza, Giorgio, Petren, Anne, Pink, Sandy, Postle, Anthony, Powell, Pippa, Rahman-Amin, Malayka, Rao, Navin, Ravanetti, Lara, Ray, Emma, Reinke, Stacey, Reynolds, Leanne, Robberechts, Martine, Roberts, Amanda, Russell, Kirsty, Rutgers, Michael, Santoninco, Marco, Schoelch, Corinna, Sjodin, Marcus, Smids, Barbara, Smith, Caroline, Smith, Jessica, Smith, Katherine M., Thorngren, John-Olof, Thornton, Bob, Thorsen, Jonathan, van de Pol, Marianne, van Geest, Marleen, Versnel, Jenny, Vink, Anton, Wald, Frans, Walker, Samantha, Weiszhart, Zsoka, Wetzel, Kristiane, Wheelock, Craig E., Wiegman, Coen, Williams, Sian, Wilson, Susan J., Woodcock, Ashley, Yang, Xian, Yeyasingham, Elizabeth, Prins, Jan-Bas, Gahlemann, Martina, Visintin, Luigi, Evans, Hazel, Puhl, Martine, Buzermaniene, Lina, Hudson, Val, Bond, Laura, de Boer, Pim, Widdershoven, Guy, Sigmund, Ralf, Supple, David, Hamerlijnck, Dominique, Negus, Jenny, Kamphuis, Julitte, Sergison, Lehanne, Onstein, Susanne, MacNee, William, Bernardini, Renato, Bont, Louis, Wecksell, Per-Ake
Publikováno v:
Journal of allergy and clinical immunology, 144(1), 70-82. Mosby Inc.
U-BIOPRED Study Group 2019, ' Stratification of asthma phenotypes by airway proteomic signatures ', The Journal of allergy and clinical immunology . https://doi.org/10.1016/j.jaci.2019.03.013
U-BIOPRED Study Group 2019, ' Stratification of asthma phenotypes by airway proteomic signatures ', The Journal of allergy and clinical immunology . https://doi.org/10.1016/j.jaci.2019.03.013
Background: Stratification by eosinophil and neutrophil counts increases our understanding of asthma and helps target therapy, but there is room for improvement in our accuracy in prediction of treatment responses and a need for better understanding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2bf8073872c4d9f64ee0c931a0f1f91
https://eprints.soton.ac.uk/429984/
https://eprints.soton.ac.uk/429984/
Autor:
Hekking, PP, Loza, MJ, Pavlidis, S, De Meulder, B, Lefaudeux, D, Baribaud, F, Auffray, C, Wagener, AH, Brinkman, P, Lutter, R, Bansal, AT, Sousa, AR, Bates, S, Pandis, Y, Fleming, LJ, Shaw, DE, Fowler, SJ, Guo, Y, Meiser, A, Sun, K, Corfield, J, Howarth, P, Bel, EH, Adcock, IM, Chung, KF, Djukanovic, R, Sterk, PJ, U-BIOPRED Study Group
Publikováno v:
European respiratory journal, 50(3). European Respiratory Society
Hekking, P-P, Loza, M J, Pavlidis, S, De Meulder, B, Lefaudeux, D, Baribaud, F, Auffray, C, Wagener, A H, Brinkman, P, Lutter, R, Bansal, A T, Sousa, A R, Bates, S A, Pandis, I, Fleming, L J, Shaw, D E, Fowler, S J, Guo, Y, Meiser, A, Sun, K, Corfield, J, Howarth, P, Bel, E H, Adcock, I M, Chung, K F, Djukanovic, R, Sterk, P J & U-BIOPRED Study Group 2017, ' Transcriptomic gene signatures associated with persistent airflow limitation in patients with severe asthma ', The European respiratory journal, vol. 50, no. 3 . https://doi.org/10.1183/13993003.02298-2016
Hekking, P-P, Loza, M J, Pavlidis, S, De Meulder, B, Lefaudeux, D, Baribaud, F, Auffray, C, Wagener, A H, Brinkman, P, Lutter, R, Bansal, A T, Sousa, A R, Bates, S A, Pandis, I, Fleming, L J, Shaw, D E, Fowler, S J, Guo, Y, Meiser, A, Sun, K, Corfield, J, Howarth, P, Bel, E H, Adcock, I M, Chung, K F, Djukanovic, R, Sterk, P J & U-BIOPRED Study Group 2017, ' Transcriptomic gene signatures associated with persistent airflow limitation in patients with severe asthma ', The European respiratory journal, vol. 50, no. 3 . https://doi.org/10.1183/13993003.02298-2016
Rationale: A proportion of severe asthma patients suffers fro m persistent airflow limitation, often associated with more symptoms and exacerbations . Little is known about the underlying mechanisms. Aiming for discovery of unexplored potential mecha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f352a8c3bfb8f5f53aee55249101c7a
https://eprints.soton.ac.uk/412905/
https://eprints.soton.ac.uk/412905/
Autor:
Kuo, CS, Pavlidis, S, Loza, M, Baribaud, F, Rowe, A, Pandis, I, Hoda, U, Rossios, C, Sousa, A, Wilson, SJ, Howarth, P, Dahlen, B, Dahlen, SE, Chanez, P, Shaw, D, Krug, N, Sandström, T, De Meulder, B, Lefaudeux, D, Fowler, S, Fleming, L, Corfield, J, Auffray, C, Sterk, PJ, Djukanovic, R, Guo, Y, Adcock, IM, Chung, KF, U-BIOPRED Project Team
Publikováno v:
Kuo, C-H S, Pavlidis, S, Loza, M, Baribaud, F, Rowe, A, Pandis, I, Hoda, U, Rossios, C, Sousa, A, Wilson, S J, Howarth, P, Dahlen, B, Dahlen, S-E, Chanez, P, Shaw, D, Krug, N, Sandström, T, De Meulder, B, Lefaudeux, D, Fowler, S, Fleming, L, Corfield, J, Auffray, C, Sterk, P J, Djukanovic, R, Guo, Y, Adcock, I M, Chung, K F & U-BIOPRED Project Team 2016, ' A Transcriptome-driven Analysis of Epithelial Brushings and Bronchial Biopsies to Define Asthma Phenotypes in U-BIOPRED ', American Journal of Respiratory and Critical Care Medicine, vol. 185, no. 4, pp. 443-455 . https://doi.org/10.1164/rccm.201512-2452OC
American journal of respiratory and critical care medicine, 195(4), 443-455. American Thoracic Society
American journal of respiratory and critical care medicine, 195(4), 443-455. American Thoracic Society
Rationale: Asthma is a heterogeneous disease driven by diverse immunologic and inflammatory mechanisms. Objectives: Using transcriptomic profiling of airway tissues, we sought to define the molecular phenotypes of severe asthma. Methods: The transcri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6ed10a2ee89d3e23a8279c05dda76a1
https://eprints.soton.ac.uk/404791/
https://eprints.soton.ac.uk/404791/