Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Alain Puisieux"'
Autor:
Valérie Bergoglio, Frédérique Fauvet, Anne-Cécile Brunac, Pierre Brousset, Jean-Sébastien Hoffmann, Mélanie K. Prodhomme, Anne-Pierre Morel, Agnès Tissier, Camille Franchet, Virginie Petrilli, Alain Puisieux, Mojgan Devouassoux-Shisheboran, Roxane M. Pommier, Caroline Moyret-Lalle
Publikováno v:
Cancer Research
Cancer Research, American Association for Cancer Research, 2021, 81 (6), pp.1595-1606. ⟨10.1158/0008-5472.CAN-20-2626⟩
Cancer Research, 2021, 81 (6), pp.1595-1606. ⟨10.1158/0008-5472.can-20-2626⟩
Cancer Research, American Association for Cancer Research, 2020, 81, pp.1595-1606. ⟨10.1158/0008-5472.can-20-2626⟩
Cancer Research, American Association for Cancer Research, 2021, 81 (6), pp.1595-1606. ⟨10.1158/0008-5472.CAN-20-2626⟩
Cancer Research, 2021, 81 (6), pp.1595-1606. ⟨10.1158/0008-5472.can-20-2626⟩
Cancer Research, American Association for Cancer Research, 2020, 81, pp.1595-1606. ⟨10.1158/0008-5472.can-20-2626⟩
A characteristic of cancer development is the acquisition of genomic instability, which results from the inaccurate repair of DNA damage. Among double-strand break repair mechanisms induced by oncogenic stress, the highly mutagenic theta-mediated end
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbc54a1b61ea7332487f44370211274a
https://hal.archives-ouvertes.fr/hal-03405580
https://hal.archives-ouvertes.fr/hal-03405580
Autor:
Luiz O. F. Penalva, Pierre Laurent-Puig, Pierre Martinez, Michelina Plateroti, Joel Uchuya-Castillo, Alain Puisieux, Nicolas Aznar, Jean-Yves Scoazec, Laetitia Marisa, Carla Frau, Clementine Le Nevé, Stéphane Ansieau, Jacques Samarut
Publikováno v:
Oncotarget
Oncotarget, Impact journals, 2018, 9 (57), pp.30979-30996. ⟨10.18632/oncotarget.25741⟩
Oncotarget, Impact journals, 2018, 9 (57), pp.30979-30996. ⟨10.18632/oncotarget.25741⟩
Our previous work demonstrated a key function of the thyroid hormone nuclear receptor TRα1, a T3-modulated transcription factor, in controlling intestinal development and homeostasis via the Wnt and Notch pathways. Importantly, increased expression
Autor:
Laurent Blanchoin, Laetitia Kurzawa, Laurent Guyon, Yoran Margaron, Alice Pinheiro, Manuel Théry, Tomoaki Nagai, Anne-Pierre Morel, Fabien Reyal, Alain Puisieux
Potential metastatic cells can dissociate from a primary breast tumor by undergoing an epithelial-to-mesenchymal transmission (EMT). Recent work has revealed that cells in intermediate states of EMT acquire an augmented capacity for tumor-cell dissem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1c5758904170e92a7b1ad42a25c2116
https://doi.org/10.1101/797654
https://doi.org/10.1101/797654
Publikováno v:
Cancer Research. 78:30-35
ZEB1 is a prime element of a network of transcription factors that controls epithelial-to-mesenchymal transition (EMT), a reversible embryonic transdifferentiation program that allows partial or complete transition from an epithelial to a mesenchymal
Autor:
Charlotte Bouard, Arnaud Vigneron, Léa Payen, Agnès Tissier, Laurent Jacqueroud, Alain Puisieux, Raphaël Terreux, Stéphane Ansieau
Publikováno v:
BMC Structural Biology, Vol 17, Iss 1, Pp 1-15 (2017)
BMC Structural Biology
BMC Structural Biology
Background The bHLH transcription factor TWIST1 plays a key role in the embryonic development and in tumorigenesis. Some loss-of-function mutations of the TWIST1 gene have been shown to cause an autosomal dominant craniosynostosis, known as the Saeth
Autor:
Mojgan Devouassoux-Shisheboran, Fabienne Allias, François Golfier, Anne Pierre Morel, Alain Puisieux, Estelle Dubruc
Publikováno v:
Virchows Archiv : an international journal of pathology. 475(1)
Although epithelial-to-mesenchymal transition (EMT) has been described in the development of complete hydatidiform moles and the invasion of the maternal decidua by trophoblasts during normal human placentation, its implication in gestational trophob
Autor:
Aurélien Marabelle, Abdelkader Selmi, Alain Puisieux, Jean Bénard, Elisabeth Garin, Maud de Saint-Jean, Michael D. Hogarty, Anne-Catherine Jallas, Sandrine Valsesia-Wittmann
Publikováno v:
Cancer Letters. 357:412-418
In neuroblastoma, MYCN amplification is associated with a worse prognosis and is a criterion used in the clinic to provide intensive treatments to children even with localized disease. In correlation with MYCN amplification, upregulation of TWIST1, a
Publikováno v:
Nature Cell Biology. 16:488-494
The plasticity of cancer cells underlies their capacity to adapt to the selective pressures they encounter during tumour development. Aberrant reactivation of epithelial-mesenchymal transition (EMT), an essential embryonic process, can promote cancer
Autor:
Joël Lachuer, Gina Tse, Gerald Saldanha, Anne Wierinckx, Stéphane Ansieau, Peter E. Hutchinson, Eftychios Papadogeorgakis, Eugene Tulchinsky, Alain Puisieux, J.E. Osborne, Louise Hill, Julie Caramel, Geoffrey Richard, Gareth J. Browne, J. Howard Pringle
Publikováno v:
Cancer Cell. 24:466-480
SummaryAberrant expression of embryonic epithelial-mesenchymal transition-inducing transcription factors (EMT-TFs) in epithelial cells triggers EMT, neoplastic transformation, stemness, and metastatic dissemination. We found that regulation and funct
Autor:
Mylène Honorat, Léa Payen, Alain Puisieux, Brigitte Manship, Charlotte Bouard, Stéphane Ansieau, Raphaël Terreux, Arnaud Vigneron
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, 2016, 44 (11), pp.5470-5489. ⟨10.1093/nar/gkw334⟩
Nucleic Acids Research, 2016, 44 (11), pp.5470-5489. ⟨10.1093/nar/gkw334⟩
The TWIST1 bHLH transcription factor controls embryonic development and cancer processes. Although molecular and genetic analyses have provided a wealth of data on the role of bHLH transcription factors, very little is known on the molecular mechanis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86033678fbadf60849b6c6cbe4a593e5
https://hal.science/hal-03625772
https://hal.science/hal-03625772