Zobrazeno 1 - 10
of 10
pro vyhledávání: '"S. Sparrow"'
Autor:
Sewell F; UK National Centre for the Replacement, Refinement & Reduction of Animals in Research (NC3Rs), Gibbs Building, 215 Euston Road, London NW1 2BE, UK. Electronic address: fiona.sewell@nc3rs.org.uk., Chapman K; UK National Centre for the Replacement, Refinement & Reduction of Animals in Research (NC3Rs), Gibbs Building, 215 Euston Road, London NW1 2BE, UK., Baldrick P; Covance Laboratories Ltd, Otley Road, Harrogate HG3 1PY, UK., Brewster D; Vertex Pharmaceuticals Inc., 50 Northern Avenue, Boston, MA 02139, USA., Broadmeadow A; Huntingdon Life Sciences Ltd, Occold, Eye, Suffolk IP23 7PX, UK., Brown P; Food and Drug Administration (FDA), 10903 New Hampshire Avenue, Silver Spring, MD 20993, USA., Burns-Naas LA; Gilead Sciences, Inc., 333 Lakeside Drive, Foster City, CA 94404, USA., Clarke J; Biogen Idec, Cambridge, MA 02142, USA., Constan A; Infinity Pharmaceuticals, 780 Memorial Drive, Cambridge, MA 02139, USA., Couch J; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, USA., Czupalla O; Bayer Pharma AG, Müllerstrasse 170, 13353 Berlin, Germany., Danks A; Charles River Laboratories, Preclinical Services, Tranent, Edinburgh EH33 2NE, UK., DeGeorge J; Merck, 770 Sumneytown Pike, Mailstop WP45-201, West Point, PA 19486, USA., de Haan L; MedImmune, Granta Park, Cambridge CB21 6GH, UK., Hettinger K; Austrian Agency for Health and Food Safety, Traisengasse 5, 1200 Vienna, Austria., Hill M; Novartis Institutes for BioMedical Research (NIBR), Basel, Switzerland., Festag M; Roche Pharmaceutical Research and Early Development, Roche Innovation Center Basel, CH - 4070 Basel, Switzerland., Jacobs A; Food and Drug Administration (FDA), 10903 New Hampshire Avenue, Silver Spring, MD 20993, USA., Jacobson-Kram D; Food and Drug Administration (FDA), 10903 New Hampshire Avenue, Silver Spring, MD 20993, USA., Kopytek S; Celgene, 86 Morris Avenue, Summit, NJ 07901, USA., Lorenz H; AbbVie Deutschland GmbH & Co. KG, Knollstrasse, 67061 Ludwigshafen, Germany., Moesgaard SG; Novo Nordisk A/S, Novo Nordisk Park, Maaloev, Denmark., Moore E; Huntingdon Life Sciences Ltd, Alconbury, Huntingdon, Cambridgeshire PE28 4HS, UK., Pasanen M; University of Eastern Finland, Faculty of Health Sciences, School of Pharmacy, Kuopio, Finland., Perry R; Pfizer Drug Safety Research and Development, 455 Eastern Point Rd., Groton, CT 06340, USA., Ragan I; Board member, NC3Rs, Gibbs Building, 215 Euston Road, London NW1 2BE, UK., Robinson S; AstraZeneca, Alderley Park, Macclesfield, Cheshire SK10 4TG, UK., Schmitt PM; Paul-Ehrlich-Institute, Federal Agency for Vaccines and Biomedicines, Langen, Germany., Short B; Allergan, Drug Safety Evaluation, 2525 Dupont Dr, RD-2A, Irvine, CA 92612-1599, USA., Lima BS; iMED, UL, University of Lisbon, Portugal., Smith D; Millenium: The Takeda Oncology Company, 40 Landsdowne St., Cambridge, MA, USA., Sparrow S; GlaxoSmithKline, Park Road, Ware, Hertfordshire SG12 0DP, UK., van Bekkum Y; Janssen Research & Development, Turnhoutseweg 30, 2340 Beerse, Belgium., Jones D; Medicines Healthcare Products Regulatory Agency (MHRA), UK.
Publikováno v:
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2014 Oct; Vol. 70 (1), pp. 413-29. Date of Electronic Publication: 2014 Jul 29.
Autor:
Chapman K; National Centre for the Replacement, Refinement & Reduction of Animals in Research (NC3Rs), London, UK., Burnett J, Corvaro M, Mitchell D, Robinson S, Sangster T, Sparrow S, Spooner N, Wilson A
Publikováno v:
Bioanalysis [Bioanalysis] 2014; Vol. 6 (22), pp. 2965-8.
Publikováno v:
Toxicology Letters
To investigate whether a normal resident microbiological flora of conventional rats influences the lethality of chemical-induced lung damage, the pneumotoxin O,S,S-trimethyl phosphorodithioate (OSSMe, 75 or 100 mg/kg, s.c.) was administered to age-ma
Publikováno v:
Archives of Toxicology. 57:260-267
Neurotoxicity and renotoxicity were compared in rats given by gastric gavage five daily doses of 8.0 mg Hg/kg methyl- or ethylmercuric chloride or 9.6 mg Hg/kg ethylmercuric chloride. Three or 10 days after the last treatment day rats treated with ei
Publikováno v:
Toxicology Letters. 27:97-102
Male Wistar (Porton) rats were dosed by gavage with trimethyltin chloride in arachis oil at doses of 3, 6 and 10 mg kg . Water consumption and urine production were monitored for 3 days after dosing and at the end of this period the rats were killed
Publikováno v:
Archives of toxicology. 59(6)
The static exposure of rats to 0.25 mg/l methyl isocyanate for 1 h resulted in damage to the epithelium of the proximal bronchioles and upper airways. Bronchiolar cells exhibited both nuclear and cytoplasmic damage; many epithelial cells, particularl
Publikováno v:
Archives of toxicology. 60(6)
The protective effect of selenite, seleno-dl-methionine and biological selenium against the renotoxicity of mercury was tested in rats. As the source of biological selenium, the liver soluble fraction of rats given 60 μmoles/kg selenite 3 days befor
Publikováno v:
Archives of toxicology. 57(3)
The extensive renal tubular necrosis that results in male rats after the intravenous injection of a single, low dose of equine kidney cadmium (Cd), zinc(Zn)-metallothionein (MT) (0.2 mg MT-bound-Cd/kg body wt.) is followed within 72 h by active regen
Autor:
S. Sparrow
Publikováno v:
Journal of Applied Toxicology. 2:III-IV
Autor:
S. Sparrow
Publikováno v:
Journal of Applied Toxicology. 6:229-229