Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Zawia, A"'
Autor:
Jaunetta Hill, Karim E. Shalaby, Syed W. Bihaqi, Bothaina H. Alansi, Benjamin Barlock, Keykavous Parang, Richard Thompson, Khalid Ouararhni, Nasser H. Zawia
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 20, p 15216 (2023)
The field of Alzheimer’s disease (AD) has witnessed recent breakthroughs in the development of disease-modifying biologics and diagnostic markers. While immunotherapeutic interventions have provided much-awaited solutions, nucleic acid-based tools
Externí odkaz:
https://doaj.org/article/9aed5ca525104b22a06f3a15bc960731
Akademický článek
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Autor:
Jaunetta Hill, Nasser H. Zawia
Publikováno v:
Cells, Vol 10, Iss 3, p 702 (2021)
Neurodegenerative disorders are desperately lacking treatment options. It is imperative that drug repurposing be considered in the fight against neurodegenerative diseases. Fenamates have been studied for efficacy in treating several neurodegenerativ
Externí odkaz:
https://doaj.org/article/d1aa080502a44fe09c2cfdb22a576e72
Autor:
Umesh T. Sankpal, Chris M. Lee, Sarah F. Connelly, Omer Kayaleh, Don Eslin, Robert Sutphin, Steven Goodison, Lina Adwan, Nasser H. Zawia, Lenard M. Lichtenberger, Riyaz Basha
Publikováno v:
Cellular Physiology and Biochemistry, Vol 32, Iss 3, Pp 675-686 (2013)
Background/Aims: The small molecule, Tolfenamic acid (TA) has shown anti-cancer activity in pre-clinical models and is currently in Phase I clinical trials at MD Anderson Cancer Center Orlando. Since specificity and toxicity are major concerns for in
Externí odkaz:
https://doaj.org/article/884ad1e677344a19ad3fac25a15012c6
Akademický článek
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Autor:
Syed Waseem Bihaqi, Reem Deeb, Asma Lahouel, Gehad M. Subaiea, Joanna K Chang, A. Masoud, Nasser H. Zawia, Miriam Dash, Aseel Eid, Foqia Mushtaq, Allison Leso
Publikováno v:
Current Alzheimer Research. 15:655-663
Background: Tangles are deposits of hyperphosphorylated tau, which are found in multiple neurodegenerative disorders that are referred to as tauopathies, of which Alzheimer's disease (AD) is the most common. Tauopathies are clinically characterized b
Autor:
Nasser H. Zawia, Jaunetta Hill
Publikováno v:
Cells, Vol 10, Iss 702, p 702 (2021)
Cells
Cells
Neurodegenerative disorders are desperately lacking treatment options. It is imperative that drug repurposing be considered in the fight against neurodegenerative diseases. Fenamates have been studied for efficacy in treating several neurodegenerativ
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Nasser H. Zawia, Syed Waseem Bihaqi, Anwar Masoud, Allison Leso, Joanna K Chang, Asma Lahouel
Publikováno v:
Exp Biol Med (Maywood)
In the healthy human brain, the protein tau serves the essential function of stabilizing microtubules. However, in a diseased state, tau becomes destabilized and aggregates into a pathogenic form that ultimately creates one of the two major hallmarks
Publikováno v:
Journal of Neurochemistry. 133:266-272
Tau and its aggregates are linked to the pathology of Alzheimer's disease (AD) and other tauopathies and, therefore, are explored as therapeutic targets for such disorders. Tau belongs to a family of microtubule-associated proteins that promote micro