Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Paul-Martin Holterhus"'
Autor:
Raphael Hirtz, Lars Libuda, Anke Hinney, Manuel Föcker, Judith Bühlmeier, Paul-Martin Holterhus, Alexandra Kulle, Cordula Kiewert, Johannes Hebebrand, Corinna Grasemann
Publikováno v:
Frontiers in Psychiatry, Vol 12 (2021)
There is a distinct increase in the prevalence of depression with the onset of puberty. The role of peripubertal testosterone levels in boys in this context is insufficiently understood and may be modulated by a functional polymorphism of the androge
Externí odkaz:
https://doaj.org/article/d4cedb4db6444c35ab23d35e5c2680ab
Autor:
Florian Schneider, Sabine Kliesch, Nina Neuhaus, Michael Zitzmann, Stefan Schlatt, Paul-Martin Holterhus, Alexandra Kulle, Joachim Wistuba
Publikováno v:
The Journal of Sexual Medicine. 18:1807-1817
Background Little information is available on steroid hormone profiles in transwomen on the day of gender affirming surgery (GAS) after gender affirming hormone therapy (GAHT). Aim We compared extended serum steroid hormone profiles of 77 transwomen
Autor:
Matthias K. Auer, Wiebke Birnbaum, Michaela F. Hartmann, Paul-Martin Holterhus, Alexandra Kulle, Anke Lux, Luise Marshall, Katarina Rall, Annette Richter-Unruh, Ralf Werner, Stefan A. Wudy, Olaf Hiort
Purpose To study differences in metabolic outcomes between testosterone and estradiol replacement in probands with complete androgen insensitivity syndrome (CAIS). Methods In this multicentre, double-blind, randomized crossover trial, 26 women with C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::936e4d44910fb86f749902406ffa90e5
https://doi.org/10.21203/rs.3.rs-1275189/v1
https://doi.org/10.21203/rs.3.rs-1275189/v1
Autor:
Jonas Ackermann, Andre Barth, Alexandra Kulle, Paul-Martin Holterhus, Reinhard W. Holl, Thomas Reinehr
Objective Gynaecomastia is frequent in pubertal boys and is regarded as a self‐limiting abnormality. However, longitudinal studies proving this hypothesis are scarce. Design Longitudinal follow‐up study (median 2.4, range 1.0‐4.8 years). Method
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7b988de38c6c66b24ed57a90e792440
Autor:
Michael Zitzmann, Sabine Kliesch, Alexandra Kulle, Julia Rohayem, Sandra Laurentino, Paul-Martin Holterhus, Eberhard Nieschlag
Publikováno v:
Clinical endocrinologyREFERENCES. 94(1)
Objective To delineate the role of gonadotropins in male androgen biosynthesis pathways. Design Case-control study. Patients and measurements Twenty five males with congenital hypogonadotropic hypogonadism (CHH) underwent hCG/rFSH and testosterone tr
Autor:
Paul-Martin Holterhus, Nadine Hornig
Publikováno v:
Molecular and Cellular Endocrinology. 523:111146
Individuals with complete androgen insensitivity syndrome show a female genital phenotype despite 46, XY gonosomes and the presence of androgen producing testes. This clinical observation indicates the resistance of the body and its cells to androgen
Autor:
Louise Marshall, Lutz Wünsch, Olaf Hiort, Ralf Werner, Ulla Döhnert, Wiebke Birnbaum, Paul-Martin Holterhus
Publikováno v:
Hormone Research in Paediatrics. 87:354-358
Background: 17β-hydroxysteroid dehydrogenase (17β-HSD) type 3 deficiency is an autosomal recessive disorder with diminished testosterone synthesis and consequently underandrogenisation. 46,XY patients with 17β-HSD type 3 deficiency are often assig
Sexual differentiation of genital anatomy in the male occurs under strict hormonal control of the fetal testes and is confined to a developmental time window between the 8th and 12th week of gestation. Wolffian ducts will develop into epididymis, vas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2e0818d84e86f786ad710ca194a1c28
https://doi.org/10.1016/b978-0-12-801238-3.65372-2
https://doi.org/10.1016/b978-0-12-801238-3.65372-2
Autor:
J Schmitz, Jürgen Hedderich, L Niermeyer, Wolfgang G. Sippell, Felix G. Riepe, Alexandra Kulle, Paul Martin Holterhus
Publikováno v:
European Journal of Endocrinology. 173:517-524
ObjectiveHeterozygosity in 21-hydroxylase deficiency (21OHD) has been associated with hyperandrogenemic symptoms in children and adults. Moreover, the carrier status is mandatory for genetic counseling. We aimed at defining a hormonal parameter for c
Autor:
Thomas Reinehr, Paul-Martin Holterhus, Caroline Knop, Juliane Rothermel, Alexandra Kulle, Christina Bosse, Nina Lass
Publikováno v:
Clinical endocrinology. 87(2)
Objective The Anti- Muellerian Hormone (AMH) has been reported as surrogate marker of antral follicles, which are the origins of hyperandrogenism in polycystic ovarian syndrome (PCOS). Therefore, AMH may be useful for the diagnosis of PCOS. The objec