Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Vincenzo Bronte"'
Autor:
Bianca Calì, Andrielly H. R. Agnellini, Chiara Cioccarelli, Ricardo Sanchez-Rodriguez, Andrea Predonzani, Giulia Ilaria Toffolo, Antonella Viola, Vincenzo Bronte, Giorgio Arrigoni, Francesco Zonta, Laura Albertoni, Claudia Mescoli, Ilaria Marigo, Barbara Molon
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Frontiers in Immunology
Reactive oxygen species, including RNS, contribute to the control of multiple immune cell functions within the tumor microenvironment (TME). Tumor-infiltrating myeloid cells (TIMs) represent the archetype of tolerogenic cells that actively contribute
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51ba54ff0723b0288d962e38ed357feb
http://hdl.handle.net/11577/3405010
http://hdl.handle.net/11577/3405010
Autor:
Marie Jo Halaby, Vincenzo Bronte, Andreas Kloetgen, Trevor J. Pugh, David G. Brooks, Kebria Hezaveh, M. Teresa Ciudad, Tracy L. McGaha, Daniel D. De Carvalho, Mengdi Guo, David H. Munn, Sara Lamorte, Aristotelis Tsirigos, Bethany L. MacLeod, Marcus O. Butler, Stefano Ugel, Tiago Medina, Ankur Chakravarthy, Pamela S. Ohashi
Publikováno v:
Sci Immunol
General control nonderepressible 2 (GCN2) is an environmental sensor controlling transcription and translation in response to nutrient availability. Although GCN2 is a putative therapeutic target for immuno-oncology, its role in shaping the immune re
Autor:
Samantha Solito, Stefano Ugel, Francesco De Sanctis, Ilaria Marigo, Laura Pinton, Susanna Mandruzzato, Vincenzo Bronte
Publikováno v:
Current protocols in immunology. 124(1)
This unit presents methods to assess the immunosuppressive properties of immunoregulatory cells of myeloid origin, such as myeloid-derived suppressor cells (MDSCs), both in vitro and in vivo in mice, as well as in biological samples from cancer patie
Autor:
Chiara Cavallini, Sara Bobisse, Manuela Iezzi, Federico Boschi, Sara Sandri, Silvia Sartoris, Andrea Sbarbati, Vincenzo Bronte, Kelly Moxley, Giovanna Ferrarini, Maria Teresa Scupoli, Rudi W. Hendriks, Stefano Ugel, Francesco De Sanctis, Alessia Lamolinara, Michael I. Nishimura, Giulio Fracasso
Publikováno v:
Cancer Research, 76(9), 2540-2551. American Association for Cancer Research Inc.
Telomerase (TERT) is overexpressed in 80% to 90% of primary tumors and contributes to sustaining the transformed phenotype. The identification of several TERT epitopes in tumor cells has elevated the status of TERT as a potential universal target for
Autor:
Alessia Lamolinara, Davide Melisi, Peter J. Murray, Aldo Scarpa, Manuela Iezzi, Giulio Fracasso, Samantha Solito, Carmine Carbone, Fulvia Vascotto, Silvio Bicciato, Bruce R. Blazar, Francesco De Sanctis, Alessandra Fiore, Geny Piro, Ugur Sahin, Giada Mondanelli, Sara Sandri, Vincenzo Bronte, Matteo Fassan, Keli L. Hippen, Stefano Ugel, Rosalinda Trovato, Silvia Sartoris, Ursula Grohmann, Rita T. Lawlor, Susanna Mandruzzato
Publikováno v:
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Immunosuppression is a hallmark of tumor progression, and treatments that inhibit or deplete monocytic myeloid-derived suppressive cells could promote anti-tumor immunity. c-FLIP is a central regulator of caspase-8-mediated apoptosis and necroptosis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acfd4cc18c28c69f032a589433baa975
http://hdl.handle.net/11577/3283867
http://hdl.handle.net/11577/3283867
Autor:
Vincenzo Bronte, Ainhoa Arina
Publikováno v:
Current Opinion in Immunology. 33:120-125
Novel models of autochthonous tumorigenesis and adoptive T cell therapy (ATT) are providing new clues regarding the pro-tumorigenic and immunosuppressive effects of myeloid-derived suppressor cells (MDSC), and their interaction with T cells. New find
Autor:
Ornella Poffe, Federico Boschi, Andrea Sbarbati, Simone Cesaro, Vincenzo Bronte, Mauro Krampera, Manuela Iezzi, Attilio Bondanza, Stefano Ugel, Silvia Sartoris, Francesco De Sanctis, Maria Teresa Scupoli, Alessandra Fiore, Sara Sartori, Sara Sandri, Michael I. Nishimura, Alessia Lamolinara, Rosalinda Trovato
Publikováno v:
Oncotarget
// Sara Sandri 1,* , Francesco De Sanctis 1,* , Alessia Lamolinara 2 , Federico Boschi 3 , Ornella Poffe 1 , Rosalinda Trovato 1 , Alessandra Fiore 1 , Sara Sartori 1 , Andrea Sbarbati 4 , Attilio Bondanza 5 , Simone Cesaro 6 , Mauro Krampera 7 , Mar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e442d15fba4e090f4b54e44f12d947fc
http://hdl.handle.net/11562/969353
http://hdl.handle.net/11562/969353
Autor:
Giovanna Lollo, Vincenzo Bronte, Guillaume Bastiat, Samantha Solito, Laura Pinton, Susanna Mandruzzato, Marion Pitorre, Ilaria Marigo, Sara Valpione, Jean-Pierre Benoit, Maria Stella Sasso
Publikováno v:
Biomaterials
Biomaterials, Elsevier, 2016, 96, pp.47-62. ⟨10.1016/j.biomaterials.2016.04.010⟩
Biomaterials, Elsevier, 2016, 96, pp.47-62. ⟨10.1016/j.biomaterials.2016.04.010⟩
International audience; Tumor-induced expansion of myeloid-derived suppressor cells (MDSCs) is known to impair the efficacy of cancer immunotherapy. Among pharmacological approaches for MDSC modulation, chemotherapy with selected drugs has a consider
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0192b60339a83e1d0dc2247cf29549a7
https://hal.archives-ouvertes.fr/hal-01392469
https://hal.archives-ouvertes.fr/hal-01392469
Autor:
Carola Ries, Amélie M. Bilocq, Barbara Molon, Andrielly H. R. Agnellini, Franz Kratochvill, Bernhard Mlecnik, Jérôme Galon, Valeria Runza, Emilia Maria Cristina Mazza, Vincenzo Bronte, Giacomo Desantis, Ilaria Marigo, Sabine Hoves, Maria Stella Sasso, Joseph E. Qualls, Silvio Bicciato, Gabriela Bindea, Stefano Ugel, Peter J. Murray, Serena Zilio, Paola Zanovello
Summary Effective cancer immunotherapy requires overcoming immunosuppressive tumor microenvironments. We found that local nitric oxide (NO) production by tumor-infiltrating myeloid cells is important for adoptively transferred CD8 + cytotoxic T cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2633d0de1ab613dab2dbd81c3e36075
http://hdl.handle.net/11577/3198559
http://hdl.handle.net/11577/3198559
Publikováno v:
Seminars in immunology. 28(1)
Immune response to tumors can be successfully oriented for therapeutic purposes, as shown by the clinical efficacy of checkpoint blockade in extending the survival of patients with certain solid and hematologic neoplasms. Nonetheless, numerous patien