Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Steven Jacobson"'
Publikováno v:
Journal of Neurovirology
Human T-lymphotropic virus type 1 (HTLV-1) is associated with adult T cell leukemia/lymphoma and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). HAM/TSP is an inflammatory disease of the spinal cord and clinically characterized b
Autor:
Ashley Vellucci, Raya Massoud, Bonita R. Bryant, Joan Ohayon, Irene Cortese, Nyater Ngouth, Unsong Oh, Bridgette Jeanne Billioux, Steven Jacobson, Yoshimi Enose-Akahata, Thomas A. Waldmann
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 6, Iss 8, Pp 1383-1394 (2019)
Annals of Clinical and Translational Neurology
Annals of Clinical and Translational Neurology
Objective Human T cell lymphotropic virus 1 (HTLV‐1)‐associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a chronic, progressive, neurological disease. Chronic activation of CD8+ T cells, as evidenced by increased spontaneous lymphopro
Autor:
Joan Ohayon, Steven Jacobson, Jun Zhu, Kory R. Johnson, Paolo A. Muraro, Alessandra de Paula Alves Sousa
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific Reports
Scientific Reports
In this study we characterized the TCR repertoire profiles in patients with chronic progressive inflammatory neurological disorders including HAM/TSP, associated with human T-cell lymphotropic virus type I (HTLV-I) infection, and multiple sclerosis (
Autor:
Ajinkya Pattekar, Pooja Jain, Ronak Loonawat, Glen M. Chew, Rashida Ginwala, Breanna Caruso, Michael J. Corley, Zafar K. Khan, Sreesha Sreedhar, Lishomwa C. Ndhlovu, Steven Jacobson
Publikováno v:
Journal of Neuroimmune Pharmacology. 12:504-520
To date, the lack of a suitable small animal model has hindered our understanding of Human T-cell lymphotropic virus (HTLV)-1 chronic infection and associated neuropathogenesis defined as HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM
Autor:
Steven Jacobson, Yoshimi Enose-Akahata
Publikováno v:
Retrovirology
Retrovirology, Vol 16, Iss 1, Pp 1-14 (2019)
Retrovirology, Vol 16, Iss 1, Pp 1-14 (2019)
Human T cell lymphotropic virus 1 (HTLV-1) is a human retrovirus and infects approximately 10–20 million people worldwide. While the majority of infected people are asymptomatic carriers of HTLV-1, only 4% of infected people develop HTLV-1-associat
Autor:
Sam Darko, David Price, Steven Jacobson, Alessandra de Paula Alves Sousa, Richard Nicholas, Kory R. Johnson, Daniel C. Douek, Paolo A. Muraro
Publikováno v:
Annals of Clinical and Translational Neurology
Objective\ud \ud Analysis of the T-cell receptor (TCR) repertoire in the cerebrospinal fluid (CSF) of patients with multiple sclerosis (MS) can reveal antigen-specific immune responses potentially implicated in the disease process. We applied a new u
Autor:
Yoshimi Enose-Akahata, Steven Jacobson, Bryan Smith, Joan Ohayon, Ashley Vellucci, Yuetsu Tanaka, Shila Azodi, Nyater Ngouth, Bridgette Jeanne Billioux, Avindra Nath, Irene Cortese
Publikováno v:
PLoS Pathogens, Vol 14, Iss 4, p e1007042 (2018)
PLoS Pathogens
PLoS Pathogens
Intrathecal antibody synthesis is a well-documented phenomenon in infectious neurological diseases as well as in demyelinating diseases, but little is known about the role of B cells in the central nervous systems. We examined B cell and T cell immun
Autor:
Breanna Caruso, Steven Jacobson, Irene Cortese, Giovanna S Brunetto, Kaylan Fenton, Joan Ohayon, Emily C. Leibovitch, Raya Massoud, Kory R. Johnson
Publikováno v:
Journal of Neurovirology
An elevated human T cell lymphotropic virus 1 (HTLV)-1 proviral load (PVL) is the main risk factor for developing HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) in HTLV-1 infected subjects, and a high cerebrospinal fluid (CSF) to
Publikováno v:
Neuroimmune Pharmacology ISBN: 9783319440200
Human T-Lymphotrophic Virus type I (HTLV-1) is an oncogenic retrovirus. Infection is associated with a variety of human diseases including HTLV-1 associated myelopathy/tropical spastic paraperesis (HAM/TSP). Large numbers of epidemiological, virologi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c805bf83eec8bcc4bbc2a5d80e9cbfb
https://doi.org/10.1007/978-3-319-44022-4_28
https://doi.org/10.1007/978-3-319-44022-4_28
Autor:
Hitoshi Ando, Atae Utsunomiya, Steven Jacobson, Yoshihisa Yamano, Tomoo Sato, Naoko Yagishita, Natsumi Araya
Publikováno v:
Viruses
Viruses, Vol 3, Iss 9, Pp 1532-1548 (2011)
Viruses, Vol 3, Iss 9, Pp 1532-1548 (2011)
Human T-lymphotropic virus type 1 (HTLV-1) is a retrovirus that is the causative agent of adult T cell leukemia/lymphoma (ATL) and associated with multiorgan inflammatory disorders, including HTLV-1-associated myelopathy/tropical spastic paraparesis