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pro vyhledávání: '"Naeun Lee"'
Autor:
Riri Kwon, Bong-Ki Hong, Kang-Gu Lee, Eunbyeol Choi, Laurent Sabbagh, Chul-Soo Cho, Naeun Lee, Wan-Uk Kim
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Journal for Immunotherapy of Cancer
Journal for Immunotherapy of Cancer
Checkpoint blockade immunotherapy (CBT) can induce long-term clinical benefits in patients with advanced cancer; however, response rates to CBT vary by cancer type. Cancers of the skin, lung, and kidney are largely responsive to CBT, while cancers of
Autor:
Kang-Gu Lee, Eunbyeol Choi, Wan-Uk Kim, Laurent Sabbagh, Naeun Lee, Chul-Soo Cho, Riri Kwon, Bong-Ki Hong
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Journal for Immunotherapy of Cancer
Journal for Immunotherapy of Cancer
BackgroundClinical efficacy of T cell-based cancer immunotherapy is limited by the lack of T cell infiltration in the tumor mass, especially in solid tumors. Our group demonstrated previously that leukocyte-specific protein 1 (LSP1), an intracellular
Publikováno v:
Pediatric Gastroenterology, Hepatology & Nutrition. 24:377
Purpose We investigated the association of effector memory (EM) CD8+ T cell and CD4+ T cell immunity with metabolic syndrome (MS). Methods Surface and intracellular staining of peripheral blood mononuclear cells was performed. Anti-interleukin-7 rece
Publikováno v:
SLE, Sjögren’s and APS – clinical aspects (other than treatment).
Background Systemic lupus erythematosus (SLE) is a systemic autoimmune disease with heterogeneous clinical manifestations and is characterised with autoreactive T cells and autoantibody overproduction by activated B cells. Objectives The aims of this
Publikováno v:
Cytokine. 58:332-335
The IL-7 receptor alpha (IL-7Rα) is the high affinity receptor for IL-7 which is essential for T cell homeostasis. We recently reported an age-associated expansion of human effector memory (EM) CD8 + T cells expressing IL-7Rα low (IL-7Rα low ), wh
We investigated whether healthy young (age ≤ 40) and elderly (age ≥ 65) people infected with cytomegalovirus (CMV) had similar levels of CD8(+) T cell cytokine production and proliferation in response to an immunodominant CMV pp65 peptide pool gi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::934bb8786d69bd33027f133462d69176
https://europepmc.org/articles/PMC3563774/
https://europepmc.org/articles/PMC3563774/
Autor:
Min Sun Shin, Insoo Kang, Albert C. Shaw, Subhasis Mohanty, Naeun Lee, Ki Soo Kang, Robert B. Belshe, Sang Doo Kim, Ruth R. Montgomery, Yinyi Yu
Publikováno v:
Clinical immunology (Orlando, Fla.). 147(2)
Alterations in T cell immunity occur with aging. Influenza causes significant morbidity and mortality in the elderly. We investigated the relationship of serum IgG responses with hemagglutinin inhibition (HI) antibody titers and the frequency of dist
Publikováno v:
Current opinion in rheumatology. 23(5)
The discovery of T helper (Th)17 cells that produce the proinflammatory cytokine IL-17 has substantially advanced our understanding of T-cell biology and autoimmunity. We will review recent findings on effector T cells, in particular Th17 cells, in l