Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Andrea Ottria"'
Autor:
Tiago Carvalheiro, Marzia Rossato, Marta Cossu, Catherina G.K. Wichers, Lorenzo Beretta, Eleni Chouri, Jonas J.W. Kuiper, Femke Bonte-Minheur, Sandra C Silva-Cardoso, Nila H. Servaas, Anneline C Hinrichs, Timothy R D J Radstake, Aridaman Pandit, Nadia Vazirpanah, Alsya J. Affandi, Maarten van der Kroef, Cornelis P. J. Bekker, Andrea Ottria, Marianne Boes, Sanne Hiddingh
Publikováno v:
Arthritis and Rheumatology. John Wiley and Sons Ltd
ObjectivesTo identify key disease pathways driving conventional dendritic cell (cDC) alterations in Systemic Sclerosis (SSc).MethodsTranscriptomic profiling was performed on peripheral blood CD1c+ cDCs (cDC2s) isolated from 12 healthy donors and 48 S
Autor:
Alsya J. Affandi, Tiago Carvalheiro, Andrea Ottria, Judith J. de Haan, Maike A.D. Brans, Maarten M. Brandt, Ralph G. Tieland, Ana P. Lopes, Beatriz Malvar Fernández, Cornelis P.J. Bekker, Maarten van der Linden, Maili Zimmermann, Barbara Giovannone, Catharina G.K. Wichers, Samuel Garcia, Michael de Kok, Giuseppina Stifano, Yan Juan Xu, M. Anna Kowalska, Maaike Waasdorp, Caroline Cheng, Susan Gibbs, Saskia C.A. de Jager, Joel A.G. van Roon, Timothy R.D.J. Radstake, Wioleta Marut
Publikováno v:
Cell Reports, 38(1):110189. Cell Press
Affandi, A J, Carvalheiro, T, Ottria, A, de Haan, J J, Brans, M A D, Brandt, M M, Tieland, R G, Lopes, A P, Fernandez, B M, Bekker, C P J, van der Linden, M, Zimmermann, M, Giovannone, B, Wichers, C G K, Garcia, S, de Kok, M, Stifano, G, Xu, Y J, Kowalska, M A, Waasdorp, M, Cheng, C, Gibbs, S, de Jager, S C A, van Roon, J A G, Radstake, T R D J & Marut, W 2022, ' CXCL4 drives fibrosis by promoting several key cellular and molecular processes ', Cell Reports, vol. 38, no. 1, 110189 . https://doi.org/10.1016/j.celrep.2021.110189
Cell Reports, 38(1). Cell Press
Affandi, A J, Carvalheiro, T, Ottria, A, de Haan, J J, Brans, M A D, Brandt, M M, Tieland, R G, Lopes, A P, Fernández, B M, Bekker, C P J, van der Linden, M, Zimmermann, M, Giovannone, B, Wichers, C G K, Garcia, S, de Kok, M, Stifano, G, Xu, Y J, Kowalska, M A, Waasdorp, M, Cheng, C, Gibbs, S, de Jager, S C A, van Roon, J A G, Radstake, T R D J & Marut, W 2022, ' CXCL4 drives fibrosis by promoting several key cellular and molecular processes ', Cell Reports, vol. 38, no. 1, 110189 . https://doi.org/10.1016/j.celrep.2021.110189
Affandi, A J, Carvalheiro, T, Ottria, A, de Haan, J J, Brans, M A D, Brandt, M M, Tieland, R G, Lopes, A P, Fernandez, B M, Bekker, C P J, van der Linden, M, Zimmermann, M, Giovannone, B, Wichers, C G K, Garcia, S, de Kok, M, Stifano, G, Xu, Y J, Kowalska, M A, Waasdorp, M, Cheng, C, Gibbs, S, de Jager, S C A, van Roon, J A G, Radstake, T R D J & Marut, W 2022, ' CXCL4 drives fibrosis by promoting several key cellular and molecular processes ', Cell Reports, vol. 38, no. 1, 110189 . https://doi.org/10.1016/j.celrep.2021.110189
Cell Reports, 38(1). Cell Press
Affandi, A J, Carvalheiro, T, Ottria, A, de Haan, J J, Brans, M A D, Brandt, M M, Tieland, R G, Lopes, A P, Fernández, B M, Bekker, C P J, van der Linden, M, Zimmermann, M, Giovannone, B, Wichers, C G K, Garcia, S, de Kok, M, Stifano, G, Xu, Y J, Kowalska, M A, Waasdorp, M, Cheng, C, Gibbs, S, de Jager, S C A, van Roon, J A G, Radstake, T R D J & Marut, W 2022, ' CXCL4 drives fibrosis by promoting several key cellular and molecular processes ', Cell Reports, vol. 38, no. 1, 110189 . https://doi.org/10.1016/j.celrep.2021.110189
Fibrosis is a major cause of mortality worldwide, characterized by myofibroblast activation and excessive extracellular matrix deposition. Systemic sclerosis is a prototypic fibrotic disease in which CXCL4 is increased and strongly correlates with sk
Autor:
Eleni Chouri, Timothy R D J Radstake, Tiago Carvalheiro, Lara Bossini-Castillo, Andrea Ottria, Ralph G. Tieland, Samuel Garcia, Javier Martin, Lenny van Bon, Jorre S. Mertens, Marzia Rossato, Laurie M. G. de Kroon, Alsya J. Affandi, Romy B. Christmann, Jasper C A Broen, Joel A G van Roon, Wioleta Marut, Aridaman Pandit
Publikováno v:
Annals of the Rheumatic Diseases, 78, 9, pp. 1249-1259
Annals of the Rheumatic Diseases, 78, 1249-1259
Digital.CSIC. Repositorio Institucional del CSIC
instname
Annals of the Rheumatic Diseases, 78, 1249-1259
Digital.CSIC. Repositorio Institucional del CSIC
instname
Objectives: Systemic sclerosis (SSc) is an autoimmune disease with unknown pathogenesis manifested by inflammation, vasculopathy and fibrosis in skin and internal organs. Type I interferon signature found in SSc propelled us to study plasmacytoid den
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03f873556ac961d4a604867b154be246
https://hdl.handle.net/2066/208664
https://hdl.handle.net/2066/208664
Autor:
Wioleta Marut, Jorre S. Mertens, Femke Bonte-Mineur, Ilse Dullemond, Kris A. Reedquist, Marc R. Kok, Andrea Ottria, Samuel Garcia, Marta Cossu, Beatriz Malvar-Fernandez, Barbara Giovannone, Alsya J. Affandi, Timothy R D J Radstake, Tiago Carvalheiro
Publikováno v:
Arthritis & Rheumatology (Hoboken, N.j.)
Arthritis and Rheumatology, 71(10), 1711. John Wiley and Sons Ltd
Arthritis and Rheumatology, 71(10), 1711. John Wiley and Sons Ltd
OBJECTIVE: To analyze the potential role of semaphorin 4A (Sema4A) in inflammatory and fibrotic processes involved in the pathology of systemic sclerosis (SSc). METHODS: Sema4A levels in the plasma of healthy controls (n = 11) and SSc patients (n = 2
Autor:
Caterina Bason, Giuseppe Patuzzo, Antonio Puccetti, Marzia Dolcino, Nicola Martinelli, Andrea Ottria, Claudio Lunardi, Alessandro Barbieri, Elisa Tinazzi
Publikováno v:
Lupus. 24:419-432
Molecular mimicry between infectious agents and normal human host cell proteins represents one of the possible mechanisms responsible for autoimmunity. Among infectious agents, human cytomegalovirus (HCMV) is an ideal candidate for involvement in aut