Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Byung Chul Jung"'
Autor:
Tae-Kyung Kim, Eun-Jin Bae, Byung Chul Jung, Minsun Choi, Soo Jean Shin, Sung Jun Park, Jeong Tae Kim, Min Kyo Jung, Ayse Ulusoy, Mi-Young Song, Jun Sung Lee, He-Jin Lee, Donato A. Di Monte, Seung-Jae Lee
Publikováno v:
Experimental & molecular medicine 54(12), 2148-2161 (2022). doi:10.1038/s12276-022-00895-w
The clinical progression of neurodegenerative diseases correlates with the spread of proteinopathy in the brain. The current understanding of the mechanism of proteinopathy spread is far from complete. Here, we propose that inflammation is fundamenta
Autor:
Benedikt Frieg, James A. Geraets, Timo Strohäker, Christian Dienemann, Panagiota Mavroeidi, Byung Chul Jung, Woojin S. Kim, Seung-Jae Lee, Maria Xilouri, Markus Zweckstetter, Gunnar F. Schröder
Publikováno v:
Communications biology 5(1), 1040 (2022). doi:10.1038/s42003-022-03948-y
Communications Biology
Communications Biology
Parkinson’s disease (PD) and Multiple System Atrophy (MSA) are progressive and unremitting neurological diseases that are neuropathologically characterized by α-synuclein inclusions. Increasing evidence supports the aggregation of α-synuclein in
Autor:
Markus Zweckstetter, Timo Strohäker, Shu-Hao Liou, Byung Chul Jung, Glenda M. Halliday, Woojin S. Kim, Seung-Jae Lee, Marina Bennati, Claudio O. Fernández, Dietmar Riedel, Stefan Becker
Publikováno v:
Nature Communications
Nature Communications 10(1), 5535 (2019). doi:10.1038/s41467-019-13564-w
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Nature Communications 10(1), 5535 (2019). doi:10.1038/s41467-019-13564-w
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Parkinson’s disease (PD) and Multiple System Atrophy (MSA) are clinically distinctive diseases that feature a common neuropathological hallmark of aggregated α-synuclein. Little is known about how differences in α-synuclein aggregate structure af
Autor:
Hugh I. Kim, Jong Yoon Han, Byung Chul Jung, Joseph A. Loo, Piriya Wongkongkathep, Min Jae Lee, Tae Su Choi, Jee Young Lee
Publikováno v:
Angewandte Chemie (International ed. in English). 57(12)
Structural variation of α-synuclein (αSyn) fibrils has been linked to the diverse etiologies of synucleinopathies. However, little is known about what specific mechanism provides αSyn fibrils with pathologic features. Herein, we demonstrate Cu(II)
Autor:
Masato Hasegawa, Chul Suk Hong, Guohua Lv, Changyoun Kim, Seung-Jae Lee, He Jin Lee, Masami Masuda-Suzukake, David Eliezer, Eliezer Masliah, Seung R. Paik, Byung Chul Jung, Jun Sung Lee, Elvira Valera
Publikováno v:
SCIENTIFIC REPORTS(6)
Scientific Reports
Scientific Reports
A single amyloidogenic protein is implicated in multiple neurological diseases and capable of generating a number of aggregate “strains” with distinct structures. Among the amyloidogenic proteins, α-synuclein generates multiple patterns of prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc3cfbe4b15d9bbdcb0d714c9a5d46a9
http://open-repository.kisti.re.kr/cube/handle/open_repository/478761.do
http://open-repository.kisti.re.kr/cube/handle/open_repository/478761.do
Autor:
Yoon Suk Kim, Seung-Jae Lee, Eun Jin Bae, Yoon Ju Lim, Byung Chul Jung, Jun Sung Lee, Choi Min Sun, He Jin Lee, Michael K. Lee
Publikováno v:
Experimental & Molecular Medicine
Amyloid fibril formation has been implicated in the pathogenesis of neurodegenerative diseases. Fibrillation generates numerous conformers. Presumably, the conformers may possess specific biological properties, thus providing a biochemical framework
Autor:
Mi-Young Song, Seokjoong Kim, Seung-Jae Lee, Eliezer Masliah, Byung Chul Jung, Jun Sung Lee, Na Young Yang, He Jin Lee, Sergio Pablo Sardi, Eun Jin Bae, Cheol Soon Lee
Publikováno v:
NATURE COMMUNICATIONS(5)
Deposition of alpha-synuclein aggregates occurs widely in the central and peripheral nervous systems in Parkinson's disease (PD). Although recent evidence has suggested that cell-to-cell transmission of alpha-synuclein aggregates is associated with t