Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Uwe T. Bornscheuer"'
Autor:
Christoph W. Grathwol, Klaus Weisz, Yoanes Maria Vianney, Andreas Link, Qingyun Tang, Ioannis V. Pavlidis, Uwe T. Bornscheuer
Publikováno v:
ChemCatChem. 12:3721-3727
Methylation of free hydroxyl groups is an important modification for flavonoids. It not only greatly increases absorption and oral bioavailability of flavonoids, but also brings new biological activities. Flavonoid methylation is usually achieved by
Autor:
Dominic Ormerod, Alessandra Romani, Uwe T. Bornscheuer, Yamini Satyawali, Matthias Höhne, Claudia Matassa
Publikováno v:
Journal of Chemical Technology & Biotechnology. 95:604-613
BACKGROUND: Amine transaminases have been extensively used for synthesizing various pharmaceutically relevant compounds, mainly in aqueous media. However, their applications are often limited by poor substrate solubility, low productivity and difficu
Autor:
Rebecca Buller, Michael Eichenberger, Felix Flachsmann, Sandro Dossenbach, Sean Hüppi, Raphael Berweger, Eric Eichhorn, Lucas Hortencio, Uwe T. Bornscheuer, Natalie Aeberli, David Patsch, Sabine Vollenweider, Francis Voirol
Publikováno v:
Angewandte Chemie (International Edition), 60(50)
Squalene-hopene cyclases (SHCs) have great potential for the industrial synthesis of enantiopure cyclic terpenoids. A limitation of SHC catalysis so far, however, has been the enzymes' strict ( S )-enantioselectivity at the stereocenter formed after
Publikováno v:
ChemCatChem. 11:3227-3233
Publikováno v:
Process Biochemistry. 80:17-25
The immense potential of transaminase-catalyzed reactions for chiral amine synthesis is often hampered by unfavorable thermodynamic equilibrium positions and product inhibition issues. In the here presented proof of concept, we demonstrate a membrane
Publikováno v:
Enzymatic Plastic Degradation
Methods in Enzymology
Methods in Enzymology-Enzymatic Plastic Degradation
Methods in Enzymology ISBN: 9780128220122
Methods in Enzymology
Methods in Enzymology-Enzymatic Plastic Degradation
Methods in Enzymology ISBN: 9780128220122
Biocatalysis has recently emerged as a powerful and eco-friendly technology in waste plastic recycling, especially for the widely used polyethylene terephthalate (PET). So far, however, a high-throughput screening assay specifically toward PET-hydrol
Autor:
Uwe T. Bornscheuer, Selin Kara, Jennifer Engel, Dominique Böttcher, Vishnu S. T. Srinivasamurthy
Publikováno v:
S.T.Srinivasamurthy, V, Böttcher, D, Engel, J, Kara, S & Bornscheuer, U T 2020, ' A whole-cell process for the production of ε-caprolactone in aqueous media ', Process Biochemistry, vol. 88, pp. 22-30 . https://doi.org/10.1016/j.procbio.2019.10.009
ε-Caprolactone is an industrially important intermediate produced in multi-10,000 ton scale annually with broad applications. We report on a whole-cell biocatalytic conversion of cyclohexanol to ε-caprolactone using the combination of alcohol dehyd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23d20bb728706abe20c8cc308d803f24
https://pure.au.dk/portal/da/publications/a-wholecell-process-for-the-production-of-caprolactone-in-aqueous-media(34b9d8fe-c6e5-4fec-bd6e-a58c1fe073c0).html
https://pure.au.dk/portal/da/publications/a-wholecell-process-for-the-production-of-caprolactone-in-aqueous-media(34b9d8fe-c6e5-4fec-bd6e-a58c1fe073c0).html
Autor:
Michael Schnürch, Marko D. Mihovilovic, Thomas Bayer, Patricia Schaaf, Moumita Koley, Florian Rudroff, Uwe T. Bornscheuer
Publikováno v:
Chemical Communications. 54:12978-12981
In this study, we present a concurrent chemo/biocatalytic one pot reaction cascade by combining a metal (Pd/Cu) assisted Liebeskind-Srogl (L-S) coupling with an enantioselective enzymatic reduction for the production of chiral amines and alcohols. Th
Publikováno v:
Applied Microbiology and Biotechnology. 102:985-994
Cytochrome P450s belong to a large and diverse group of heme-containing enzymes. These monooxygenases catalyze the incorporation of a single atom of molecular oxygen into their substrate. In contrast to most other enzymes, the activity of P450 enzyme
Autor:
Harald Gröger, Sandy Schmidt, Selin Kara, Andreas Liese, Uwe T. Bornscheuer, Christian Scherkus
Publikováno v:
Biotechnology and Bioengineering. 114:1215-1221
A computational approach for the simulation and prediction of a linear three-step enzymatic cascade for the synthesis of ϵ-caprolactone (ECL) coupling an alcohol dehydrogenase (ADH), a cyclohexanone monooxygenase (CHMO), and a lipase for the subsequ