Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Udai Kammula"'
Publikováno v:
Journal of Medicinal Chemistry. 32:1043-1051
Adenosine modulates a variety of physiological functions.1 It acts as an inhibitor of neuronal firing and the release of neurotransmitters,1b an inhibitor of platelet aggregation,1c a cardiac depressant and a vasodilator,1d a vasoconstrictor1e (e.g.,
Sulfur-Containing 1,3-Dialkylxanthine Derivatives as Selective Antagonists at A1-Adenosine Receptors
Autor:
Kenneth A. Jacobson, Udai Kammula, Barton James Bradbury, John L. Neumeyer, Jean Michel Campagne, Wolfgang Pfleiderer, Leonidas Kiriasis, Sherrie Secunda, Suzanne Barone, John W. Daly
Sulfur-containing analogues of 8-substituted xanthines were prepared in an effort to increase selectivity or potency as antagonists at adenosine receptors. Either cyclopentyl or various aryl substituents were utilized at the 8-position, because of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f911e9c715e2f39bed6c2ea50509006b
https://europepmc.org/articles/PMC3479653/
https://europepmc.org/articles/PMC3479653/