Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Alkhalil, M"'
Publikováno v:
Organic Letters. 23:3259-3263
Monofluoroalkenes normally act as metabolically stable bioisosteres for amide groups (-NH-CO-) and have widespread applications in drug discovery. Additionally, they are widely used as building blocks in organic synthesis. In this study, the Cu/Pd-ca
Publikováno v:
Chemical Communications. 57:6400-6403
Borylative difunctionalization of alkenes has emerged as a powerful approach for synthesizing highly functionalized molecules. Herein, dual Cu/Pd-catalysed borylfluoroallylation of alkenes was smoothly achieved by using gem-difluorinated cyclopropane
Publikováno v:
Organic Letters. 22:1414-1419
Herein, we describe a palladium-catalyzed alkynylation of gem-difluorinated cyclopropanes via C–C bond activation/C–F bond cleavage, followed by C–C(sp) coupling. The new approach proceeds with broad substrate scope under mild reaction conditio
Publikováno v:
Organic Letters. 21:5645-5649
A palladium-catalyzed cross-coupling of gem-difluorinated cyclopropanes with boronic acids, providing the corresponding arylated/alkenylated/alkylated 2-fluoroallylic scaffolds, is generated. This new approach has good functional group compatibility