Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Vitale, R."'
Autor:
Daniele Ciceri, Luciano De Petrocellis, Orazio Taglialatela-Scafati, Lolita Arnoldi, Pietro Amodeo, Giuseppina Chianese, Emanuele Benetti, Rosa Maria Vitale, Eric de Combarieu, Aniello Schiano-Moriello, Annalisa Lopatriello, Diego Caprioglio, Daiana Mattoteia, Giovanni Appendino
Publikováno v:
Journal of natural products
83 (2020): 2727–2736. doi:10.1021/acs.jnatprod.0c00668
info:cnr-pdr/source/autori:Chianese, Giuseppina; Lopatriello, Annalisa; Schiano-Moriello, Aniello; Caprioglio, Diego; Mattoteia, Daiana; Benetti, Emanuele; Ciceri, Daniele; Arnoldi, Lolita; De Combarieu, Eric; Vitale, Rosa M.; Amodeo, Pietro; Appendino, Giovanni; De Petrocellis, Luciano; Taglialatela-Scafati, Orazio/titolo:Cannabitwinol, a Dimeric Phytocannabinoid from Hemp, Cannabis sativa L., Is a Selective Thermo-TRP Modulator/doi:10.1021%2Facs.jnatprod.0c00668/rivista:Journal of natural products (Print)/anno:2020/pagina_da:2727/pagina_a:2736/intervallo_pagine:2727–2736/volume:83
83 (2020): 2727–2736. doi:10.1021/acs.jnatprod.0c00668
info:cnr-pdr/source/autori:Chianese, Giuseppina; Lopatriello, Annalisa; Schiano-Moriello, Aniello; Caprioglio, Diego; Mattoteia, Daiana; Benetti, Emanuele; Ciceri, Daniele; Arnoldi, Lolita; De Combarieu, Eric; Vitale, Rosa M.; Amodeo, Pietro; Appendino, Giovanni; De Petrocellis, Luciano; Taglialatela-Scafati, Orazio/titolo:Cannabitwinol, a Dimeric Phytocannabinoid from Hemp, Cannabis sativa L., Is a Selective Thermo-TRP Modulator/doi:10.1021%2Facs.jnatprod.0c00668/rivista:Journal of natural products (Print)/anno:2020/pagina_da:2727/pagina_a:2736/intervallo_pagine:2727–2736/volume:83
Cannabitwinol (CBDD, 3), the second member of a new class of dimeric phytocannabinoids in which two units are connected by a methylene bridge, was isolated from a hemp (Cannabis sativa L.) industrial extract. The structural characterization of cannab
Autor:
Jochen Antel, Rosa Maria Vitale, Claudiu T. Supuran, Carlo Pedone, Andrea Scozzafava, Giuseppina De Simone, Pietro Amodeo, Wurl Michael
Publikováno v:
Bioorganic & medicinal chemistry
15 (2007): 4152–4158. doi:10.1016/j.bmc.2007.03.070
info:cnr-pdr/source/autori:Vitale RM; Pedone C; Amodeo P; Antel J; Wurl M; Scozzafava A; Supuran CT; De Simone G/titolo:Molecular modeling study for the binding of zonisamide and topiramate to the human mitochondrial carbonic anhydrase isoform VA/doi:10.1016%2Fj.bmc.2007.03.070/rivista:Bioorganic & medicinal chemistry (Print)/anno:2007/pagina_da:4152/pagina_a:4158/intervallo_pagine:4152–4158/volume:15
15 (2007): 4152–4158. doi:10.1016/j.bmc.2007.03.070
info:cnr-pdr/source/autori:Vitale RM; Pedone C; Amodeo P; Antel J; Wurl M; Scozzafava A; Supuran CT; De Simone G/titolo:Molecular modeling study for the binding of zonisamide and topiramate to the human mitochondrial carbonic anhydrase isoform VA/doi:10.1016%2Fj.bmc.2007.03.070/rivista:Bioorganic & medicinal chemistry (Print)/anno:2007/pagina_da:4152/pagina_a:4158/intervallo_pagine:4152–4158/volume:15
Zonisamide and topiramate are two antiepileptic drugs known to induce weight loss in epilepsy patients. These molecules were recently shown to act as carbonic anhydrase (CA) inhibitors, being presumed that the weight loss may be due to the inhibition
Autor:
Michele Saviano, Bernard Kaptein, Ettore Benedetti, Quirinus B. Broxterman, Fernando Formaggio, Rosa Maria Vitale, Claudio Toniolo, Marco Crisma
Publikováno v:
Macromolecules
35 (2002): 4204–4209.
info:cnr-pdr/source/autori:Saviano M., Benedetti E., Vitale R M., Kaptein B., Broxterman Q B., Crisma M., Formaggio F., Toniolo C./titolo:X-ray Diffraction Analysis and Conformational Energy Computations of b-Turn and 310-Helical Peptides Based on a-Amino Acids with an Olefinic Side Chain. Implications for Ring-Closing Metathesis./doi:/rivista:Macromolecules (Print)/anno:2002/pagina_da:4204/pagina_a:4209/intervallo_pagine:4204–4209/volume:35
35 (2002): 4204–4209. doi:10.1021/ma012043l
info:cnr-pdr/source/autori:Saviano M., Benedetti E., Vitale R.M., Kaptein B., Broxterman Q.B., Crisma M., Formaggio F., Toniolo C./titolo:X-ray diffraction analysis and conformational energy computations of beta-turn and 3(10)-helical peptides based on an alpha-amino acid with an olefinic side chain. Implications for ring-closing metathesis/doi:10.1021%2Fma012043l/rivista:Macromolecules (Print)/anno:2002/pagina_da:4204/pagina_a:4209/intervallo_pagine:4204–4209/volume:35
35 (2002): 4204–4209.
info:cnr-pdr/source/autori:Saviano M., Benedetti E., Vitale R M., Kaptein B., Broxterman Q B., Crisma M., Formaggio F., Toniolo C./titolo:X-ray Diffraction Analysis and Conformational Energy Computations of b-Turn and 310-Helical Peptides Based on a-Amino Acids with an Olefinic Side Chain. Implications for Ring-Closing Metathesis./doi:/rivista:Macromolecules (Print)/anno:2002/pagina_da:4204/pagina_a:4209/intervallo_pagine:4204–4209/volume:35
35 (2002): 4204–4209. doi:10.1021/ma012043l
info:cnr-pdr/source/autori:Saviano M., Benedetti E., Vitale R.M., Kaptein B., Broxterman Q.B., Crisma M., Formaggio F., Toniolo C./titolo:X-ray diffraction analysis and conformational energy computations of beta-turn and 3(10)-helical peptides based on an alpha-amino acid with an olefinic side chain. Implications for ring-closing metathesis/doi:10.1021%2Fma012043l/rivista:Macromolecules (Print)/anno:2002/pagina_da:4204/pagina_a:4209/intervallo_pagine:4204–4209/volume:35
We describe the X-ray diffraction structure of the terminally protected dipeptide amide Boc-Aib-L-Mag-NHBzl (Aib is alpha-aminoisobutyric acid and Mag is C-alpha-methyl, C-a-allyl-glycine) and the results of conformational energy computations on Ac-L
Autor:
Luisa Mengatto, Andrea Cavalli, Anna Berteotti, Romina Vitale, Stefano Ponzano, Tiziano Bandiera, Fabio Bertozzi, Giovanni Bottegoni, Rita Petracca, Daniele Piomelli
Publikováno v:
Ponzano, S; Berteotti, A; Petracca, R; Vitale, R; Mengatto, L; Bandiera, T; et al.(2014). Synthesis, biological evaluation, and 3D QSAR study of 2-methyl-4-oxo-3-oxetanylcarbamic acid esters as N-acylethanolamine acid amidase (NAAA) inhibitors. Journal of Medicinal Chemistry, 57(23), 10101-10111. doi: 10.1021/jm501455s. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/4058m5gd
© 2014 American Chemical Society. N-(2-Oxo-3-oxetanyl)carbamic acid esters have recently been reported to be noncompetitive inhibitors of the N-acylethanolamine acid amidase (NAAA) potentially useful for the treatment of pain and inflammation. In th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7172cc376699c5581178da5c0d22925a
https://hdl.handle.net/11576/2688382
https://hdl.handle.net/11576/2688382
Autor:
Laura Zaccaro, Benedetto Di Blasio, Carla Isernia, Michele Saviano, Carlo Pedone, Pietro Amodeo, Roberto Fattorusso, Rosa Maria Vitale
Publikováno v:
ChemBioChem
4 (2003): 73–81.
info:cnr-pdr/source/autori:Vitale, Rosa Maria; Zaccaro, Laura; Di Blasio, Benedetto; Fattorusso, Roberto; Isernia, Carla; Amodeo, Pietro; Pedone, Carlo; Saviano, Michele/titolo:Conformational features of human melanin-concentrating hormone: an NMR and computational analysis/doi:/rivista:ChemBioChem (Print)/anno:2003/pagina_da:73/pagina_a:81/intervallo_pagine:73–81/volume:4
4 (2003): 73–81.
info:cnr-pdr/source/autori:Vitale, Rosa Maria; Zaccaro, Laura; Di Blasio, Benedetto; Fattorusso, Roberto; Isernia, Carla; Amodeo, Pietro; Pedone, Carlo; Saviano, Michele/titolo:Conformational features of human melanin-concentrating hormone: an NMR and computational analysis/doi:/rivista:ChemBioChem (Print)/anno:2003/pagina_da:73/pagina_a:81/intervallo_pagine:73–81/volume:4
The conformational features of human melanin-concentrating hormone (hMCH) [Asp1-Phe2-Asp3-Met4-Leu5-Arg6-cyclo(S[bond]S)(Cys7-Met8-Leu9-Gly10-Arg11-Val12-Tyr13-Arg14-Pro15-Cys16)-Trp17-Gln18-Val19], in water and in a CD(3)CN/H(2)O (1:1 v/v) mixture a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7da79eee36e7a30dc3bf8742a3ceff29
http://hdl.handle.net/11588/166122
http://hdl.handle.net/11588/166122
Autor:
Michele Saviano, Roberto Fattorusso, Ettore Benedetti, Carlo Pedone, Giuseppe Perretta, Rosa Maria Vitale, Laura Zaccaro, Enrico M. Bucci
Publikováno v:
Journal of peptide science
9 (2003): 90–105.
info:cnr-pdr/source/autori:Zaccaro, Laura; Bucci, Enrico; Vitale, Rosa Maria; Perretta, Giuseppe; Fattorusso, Roberto; Benedetti, Ettore; Saviano, Michele; Pedone, Carlo/titolo:Synthetic peptides mimicking the interleukin-6%2Fgp130 interaction: A two-helix bundle system. Design and conformational studies/doi:/rivista:Journal of peptide science (Print)/anno:2003/pagina_da:90/pagina_a:105/intervallo_pagine:90–105/volume:9
9 (2003): 90–105.
info:cnr-pdr/source/autori:Zaccaro, Laura; Bucci, Enrico; Vitale, Rosa Maria; Perretta, Giuseppe; Fattorusso, Roberto; Benedetti, Ettore; Saviano, Michele; Pedone, Carlo/titolo:Synthetic peptides mimicking the interleukin-6%2Fgp130 interaction: A two-helix bundle system. Design and conformational studies/doi:/rivista:Journal of peptide science (Print)/anno:2003/pagina_da:90/pagina_a:105/intervallo_pagine:90–105/volume:9
The objective of our study was to mimic in a typical reductionist approach the molecular interactions observed at the interface between the gp130 receptor and interleukin-6 during formation of their complex. A peptide system obtained by reproducing s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38c6772a17d839f19e391bdc02f2ed34
http://hdl.handle.net/11588/131094
http://hdl.handle.net/11588/131094
Autor:
Quirinus B. Broxterman, Bernard Kaptein, Johan Kamphuis, Michele Saviano, Cristina Peggion, Marco Crisma, Rosa Iacovino, Claudio Toniolo, Fernando Formaggio, Rosa Maria Vitale, Ettore Benedetti
A complete series of Nα-protected, monodispersed homooligopeptide esters to the pentamer level from L-Cα-methyl,Cα-allylglycine (L-Mag) have been synthesized step-by-step in solution and fully characterized. The solution preferred conformation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acbb6ae7fe1f2e37297458582ec0d93b
http://hdl.handle.net/11588/131079
http://hdl.handle.net/11588/131079