Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Kay-Hooi Khoo"'
Autor:
Akiko Kinoshita-Toyoda,‡, Kay-Hooi Khoo, Makiko Sugiura, Shuhei Yamada, Kazuyuki Sugahara, Howard R. Morris, and Anne Dell, Stuart M. Haslam
Publikováno v:
Biochemistry. 43:11063-11074
Oversulfated chondroitin sulfate E (CS-E) derived from squid cartilage exhibits intriguing biological activities, which appear to reflect the biological activities of mammalian CS chains containing the so-called E disaccharide unit [GlcAbeta1-3GalNAc
Autor:
Delphi Chatterjee, Mark R. Guy, Kay-Hooi Khoo, Patrick J. Brennan, Gurdyal S. Besra, Jillian R Brown, Adam Barker, Robert A. Field, Ravinder K. Grewal
Publikováno v:
Bioorganic & Medicinal Chemistry. 9:815-824
A series of synthetic mannosides was screened in a cell-free system for their ability to act as acceptor substrates for mycobacterial mannosyltransferases. Evaluation of these compounds demonstrated the incorporation of [14C]Man from GDP-[14C]Man int
Publikováno v:
Glycobiology. 11:149-163
Schistosomal egg N-glycans are the only examples in nature that have been structurally shown to contain beta2-xylosylation, alpha6-fucosylation, and alpha3-fucosylation on the N,N'-diacetyl chitobiose core. We present evidence that core difucosylated
Autor:
Julia M. Inamine, Merrill L. Schaeffer, Gurdyal S. Besra, Patrick J. Brennan, Kay-Hooi Khoo, John T. Belisle, Delphi Chatterjee
Publikováno v:
Journal of Biological Chemistry. 274:31625-31631
The biosynthesis of lipoarabinomannan (LAM), a key mycobacterial lipoglycan that has been implicated in numerous immunoregulatory functions, was examined utilizing D-mannosamine (ManN) as a tool to identify mannosyltransferase genes involved in LAM s
Publikováno v:
Glycobiology. 9:125-131
We employed a genetic approach to study protein glycosylation in the procyclic form of the parasite Trypanosoma brucei. Two different mutant parasites, ConA 1-1 and ConA 4-1, were isolated from mutagenized cultures by selecting cells which resisted k
Publikováno v:
Molecular and Biochemical Parasitology. 86:237-248
Infection by the tapeworm Echinococcus granulosus in the intermediate host results in the development of a hydatid cyst which contains the protoscoleces within a fluid-filled cavity enclosed by the bilayered cyst membrane. N -glycans were enzymatical
Autor:
Katrina M. Houston, Anne Dell, William Harnett, Kay-Hooi Khoo, Howard R. Morris, Stuart M. Haslam
Publikováno v:
Molecular and Biochemical Parasitology. 85:53-66
The major excretory-secretory product of the rodent filarial nematode Acanthocheilonema viteae is a 62 kDa glycoprotein (ES-62), which has phosphorylcholine, attached to the N-linked carbohydrates. In this paper, we describe structural studies of N-g
Publikováno v:
Glycobiology. 7:653-661
The granulomatous pathology in human intestinal schistosomiasis is induced primarily by the egg antigens of schistosome, a parasitic trematode. Glycolipids and glycoproteins were extracted from the eggs of the two major species which infect human, Sc
Autor:
Mariko Iwasaki, Yutaka Muto, Howard R. Morris, Ken Kitajima, Sadako Inoue, Kay-Hooi Khoo, Anne Dell, Tomohiko Taguchi, Yasuo Inoue
Publikováno v:
European Journal of Biochemistry. 238:357-367
This study represents the first detailed investigation of the nature of highly sulfated (keratan-sulfate-like) complex-type asparagine-linked glycans having a tetraantennary core structure and shows the effectiveness of fast-atom-bombardment mass spe
Autor:
Delphi Chatterjee, Howard R. Morris, Kay-Hooi Khoo, Philip Draper, Anne Dell, Patrick J. Brennan
Publikováno v:
Journal of Biological Chemistry. 271:12333-12342
Mycobacterium "habana" strain TMC 5135, which has been proposed as a vaccine against both leprosy and tuberculosis, is considered to be a strain of serotype I of the recognized species Mycobacterium simiae. We have now shown that each of these strain