Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Xiaofeng Tian"'
Autor:
Yan H; 1Department of Pharmacology, Dalian Medical University, Dalian, China. 2Department of Pharmacy, Second Affiliated Hospital of Dalian Medical University, Dalian, China. 3Department of General Surgery, Second Affiliated Hospital of Dalian Medical University, Dalian, China., Jihong Y, Feng Z, Xiaomei X, Xiaohan Z, Guangzhi W, Zhenhai M, Dongyan G, Xiaochi M, Qing F, Kexin L, Xiaofeng T
Publikováno v:
Critical care medicine [Crit Care Med] 2014 May; Vol. 42 (5), pp. e373-81.
Autor:
Zhenlu Li, Xue Shi, Anlong Ji, Chunchun Ding, Dongyan Gao, Yang Li, Junjun Zhou, Jihong Yao, Zhecheng Wang, Dongcheng Feng, Xiaofeng Tian, Yan Zhao
Publikováno v:
Toxicology and Applied Pharmacology. 350:21-31
In recent years, alcoholic liver disease (ALD) has emerged as a growing public health problem worldwide. β-catenin plays an important role in the growth, development, regeneration and metabolic activity of the liver. Salvianolic acid A (SalA) is a w
Autor:
Yan Hu, Zhecheng Wang, Yan Zhao, Dongcheng Feng, Yang Li, Jihong Yao, Junjun Zhou, Xiaofeng Tian, Chao Wang, Fan Tang, Huanyu Zhao
Publikováno v:
Pharmacological Research. 128:327-337
Quiescent hepatic stellate cell (HSC) activation and subsequent conversion into myofibroblasts is the central event in hepatic fibrosis pathogenesis. Epithelial-mesenchymal transition (EMT), another vital participant in liver fibrosis, has the potent
Autor:
Huanyu Zhao, Ning Zhang, Ruimin Sun, Yan Zhao, Jihong Yao, Xiaofeng Tian, Rong Fu, Zhecheng Wang, Xue Shi, Ruiwen Wang, Fan Tang
Publikováno v:
RSC Advances. 8:20411-20422
Salvianolic acid A (SalA) is a water-soluble phenolic carboxylic acid extracted from Salvia miltiorrhiza that has extensive pharmacological activities and plays an essential role in liver disease treatment. However, the mechanism of SalA in treating
Autor:
Li Wang, Xiaofeng Tian, Dongyan Gao, Yan Hu, Chunchun Ding, Xue Shi, Yang Li, Jihong Yao, Dongcheng Feng, Yan Zhao
Publikováno v:
Toxicology and Applied Pharmacology. 339:172-180
Carnosic acid (CA), a major bioactive component in rosemary extract, has many biological and pharmaceutical activities. Smad3 acetylation can regulate the transcription of type I α2 collagen (COL1A2), which is the major component of the extracellula
Autor:
Yan Zhao, Chao Wang, Zhenlu Li, Dongyan Gao, Shuai Zhang, Xiaofeng Tian, Ting Xu, Ruiwen Wang, Jihong Yao, Yan Hu, Junjun Zhou, Jie Zhu
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Frontiers in Pharmacology
Frontiers in Pharmacology
Background: Endoplasmic reticulum stress (ER stress) plays a critical role in the pathogenesis of liver fibrosis; thus, it can be a potential therapeutic target of fibrosis. However, the mechanism of ER stress regulation in fibrosis, particularly thr
Autor:
Yang Lu, Yan Hu, Huirong Jing, Xiaohan Zhai, Yuan Lin, Wei Xu, Xiaofeng Tian, Dongyan Gao, Mingzhu Li, Jihong Yao
Publikováno v:
Toxicology Letters. 228:67-74
Salvianolic acid B (SalB) is isolated from the traditional Chinese medical herb salvia miltiorrhiza. It has many biological and pharmaceutical activities. This study aimed to investigate the effect of SalB on acute ethanol-induced hepatic injury in r
Autor:
Wen Shan, Xiaofeng Tian, Guangzhi Wang, Yang Li, Yan Hu, Zhenlu Li, Yongfu Zhao, Dongcheng Feng, Guo Zu, Jihong Yao
Publikováno v:
Antioxidantsredox signaling. 24(17)
Reactive oxygen species (ROS) generation and massive epithelial apoptosis are critical in the pathogenesis of intestinal ischemia/reperfusion (I/R) injury. We previously found that the Sirtuin 1 (SIRT1)-mediated antioxidant pathway was impaired in th
Autor:
Guangzhi Wang, Kexin Liu, Lili Gao, Chunchun Ding, Jihong Yao, Wen Shan, Yan Zhao, Feng Zhang, Wenjing Zeng, Xiaofeng Tian, Xue Shi, Yan Hu, Ning Zhang
Publikováno v:
Molecular nutritionfood research. 60(9)
cope Carnosic acid (CA), which is extracted from rosemary, displays multiple pharmacological activities. This study aimed to investigate the effects of CA on chronic alcoholic liver injury and to elucidate the related mechanisms. Methods and results
Autor:
Xiaochi Ma, Lili Gao, Jihong Yao, Wenjing Zeng, Zhenlu Li, Wei Xu, Jinyong Peng, Ning Zhang, Yan Hu, Wen Shan, Xiaofeng Tian, Guangzhi Wang, Dongyan Gao
Publikováno v:
Scientific Reports
The inflammatory mediator high-mobility group box 1 (HMGB1) plays a critical role in the pathogenesis of non-alcoholic fatty liver disease (NAFLD). However, the regulation of HMGB1 in NAFLD, particularly through sirtuin 1 (SIRT1), remains unclear. In