Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Zhengwei Zhu"'
Autor:
Minglong Cai, Yong Cui, Lu Liu, Xue Shen, Ying Qiu, Yujun Sheng, Hui Li, Danfeng Qian, Zhengwei Zhu, Songke Shen, He Huang, Leilei Wen
Publikováno v:
Annals of Human Genetics. 84:221-228
Single-nucleotide polymorphisms (SNPs) in the UHRF gene have been shown to be associated with systemic lupus erythematosus (SLE) in European and Hong Kong Chinese, but statistically significant evidence for association has not been found in a mainlan
Autor:
Sen Yang, Yujun Sheng, Xianfa Tang, Caihong Zhu, Xiaoqun Luo, Wenjun Wang, Yang Li, Fusheng Zhou, Yaohua Zhang, Xuejun Zhang, Xiaodong Zheng, Xianbo Zuo, Shengxiu Liu, Dong-Qing Ye, Sheng-an Chen, Gang Chen, Qian Wenjun, Fanping Yang, Zhengwei Zhu, Hui Cheng, Huayang Tang, Jinping Gao, Liangdan Sun, Zaixing Wang, Qinyuan Zhu
Publikováno v:
Journal of Investigative Dermatology. 138:2307-2314
To identify possible additional genetic susceptibility loci for pemphigus vulgaris (PV), we performed a genome-wide association study of 240 PV patients and 1,031 control individuals, and we selected the top single nucleotide polymorphisms for replic
Autor:
Gang Chen, Yujun Sheng, Elisabeth Mangold, Xiazhou Fu, Xianbo Zuo, Yong Cheng, Chuanqi Qin, Xiaodong Zheng, Zhengwei Zhu, Mary L. Marazita, Ingo Ruczinski, Liuyan Meng, Yanqin Yu, Jianjun Liu, Liangdan Sun, Miao He, Fusheng Zhou, Terri H. Beaty, Wenjun Wang, Zhuan Bian, Yuchuan Fu, Kerstin U. Ludwig, Yaling Song, Zhongyin Liu, Xinhuan Wang, Hansong Yan, Xuejun Zhang, Bo Liang, Jiebing Hao, Jinping Gao
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Nature Communications
Nature Communications
Non-syndromic cleft lip with palate (NSCLP) is the most serious sub-phenotype of non-syndromic orofacial clefts (NSOFC), which are the most common craniofacial birth defects in humans. Here we conduct a GWAS of NSCLP with multiple independent replica
Autor:
Chao Yang, Yan Lin, Yinjuan Shi, Lu Liu, Leilei Wen, Sen Yang, Yujun Sheng, Yong Cui, Xuejun Zhang, Changbing Shen, Yajie Zheng, Zhengwei Zhu, Xianyong Yin
Publikováno v:
G3: Genes|Genomes|Genetics
G3: Genes, Genomes, Genetics, Vol 6, Iss 6, Pp 1503-1511 (2016)
G3: Genes, Genomes, Genetics, Vol 6, Iss 6, Pp 1503-1511 (2016)
We aimed to elucidate the cell types, tissues, and pathways influenced by common variants in systemic lupus erythematosus (SLE). We applied a nonparameter enrichment statistical approach, termed SNPsea, in 181 single nucleotide polymorphisms (SNPs) t
Autor:
Xianbo Zuo, Yujun Sheng, Shu Li, Suli Zhao, Xianfa Tang, Jinping Gao, Anping Zhang, Liangdan Sun, Wei-yi Yao, Qian Pan, Wenjun Wang, Xiaodong Zheng, Fusheng Zhou, Zhengwei Zhu
Publikováno v:
Immunogenetics. 67:347-354
Generalized vitiligo is an autoimmune disease characterized by melanocyte loss, which results in patchy depigmentation of skin and hair, and is associated with an elevated risk of other immune-related diseases. However, there is no reported study on
Autor:
Zaixing Wang, Liangdan Sun, Jianping Wu, Hui Li, Juan Du, Xiaodong Zheng, Yujun Sheng, Xianyong Yin, Sen Yang, Wenjun Wang, Ming Zeng, Long Jiang, Huayang Tang, Xing Fan, Yong Cui, Jinping Gao, Zhengwei Zhu, Xuejun Zhang, Li Meng, Weiran Li, Shengxiu Liu, Yang Li
Publikováno v:
The Journal of Dermatology. 42:608-612
In our previous meta-analysis of genome-wide association study, we identified the single nucleotide polymorphism (SNP) rs4948496 (P = 5.1 × 10(-11) , odds ratio [OR] = 0.85) within the ARID5B gene associated with systemic lupus erythematosus (SLE) i
Autor:
Jinping Gao, Sen Yang, Bo Liang, Caihong Zhu, Gang Chen, Xuejun Zhang, Jinhua Xu, Fusheng Zhou, Yujun Sheng, Chen Zhou, Zhanguo Li, Xianyong Yin, Shengxiu Liu, Xueqing Yu, Jingying Sun, Jun Zhu, Yuanjia Tang, Xianbo Zuo, Yantao Ding, Anjana Kafle, Huayang Tang, Yi Zhou, Jianping Guo, Chao Yang, Xiaodong Zheng, Lili Tang, Tamilselvi Elango, Yong Cui, Feng Li, Xuan Zhang, Min Gao, Ke Xue, Pan Li, Zhengwei Zhu, Nan Shen, Zaixing Wang, Pei-Guang Wang, Yaohua Zhang, Leilei Wen, Xing Fan, Anping Zhang, Meng Wang, Liangdan Sun, Ruixing Yu, Lu Liu, Yuyan Cheng, Feng-Li Xiao
Publikováno v:
Annals of the rheumatic diseases. 77(3)
ObjectivesSystemic lupus erythematosus (SLE) is a chronic autoimmune disease of considerable genetic predisposition. Genome-wide association studies have identified tens of common variants for SLE. However, the majority of them reside in non-coding s
Autor:
Fusheng Zhou, Hongyan Wang, Lulu Yang, Yan Huang, Yaohua Zhang, Chao Yang, Xuejun Zhang, Lu Liu, Huayang Tang, Wenjun Wang, Leilei Wen, Yong Cui, Sen Yang, Liyun Chen, Zhengwei Zhu, Xianbo Zuo, Yujun Sheng
Publikováno v:
Annals of human genetics. 82(4)
The polymorphism of PRKCB has been proven to be associated with systemic lupus erythematosus (SLE) in our previous study. We aimed to investigate the relationship between expression of PRKCB mRNA and the Disease Activity Index (SLEDAI) and manifestat
Autor:
Xianbo Zuo, Yujun Sheng, Xuejun Zhang, Fang Cheng, Xing Fan, Caihong Zhu, Liying Fu, Chao Yang, Longnian Li, Xiaodong Zheng, Zaixing Wang, Leilei Wen, Zhengwei Zhu, Fusheng Zhou, Hequn Huang, Huimin Guo, Wenjun Wang, Yuyan Cheng, Jinfa Dou, Liangdan Sun, Lili Tang, Shengxiu Liu, Lei Ye
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 10, p e0186067 (2017)
PLoS ONE, Vol 12, Iss 10, p e0186067 (2017)
Researchers have learned that nearly all conditions and diseases have a genetic component. With the benefit of technological advances, many single-nucleotide polymorphisms (SNPs) have been found to be associated with the risk of complex disorders by
Autor:
Sheng-Quan Zhang, Fusheng Zhou, Lu Liu, Leilei Wen, Yan Lin, Yujun Sheng, Yong Cui, Yuyan Cheng, Sen Yang, Xuejun Zhang, Zhengwei Zhu, Yan Chang, Chao Yang, Xiaodong Zheng, Lulu Yang
Publikováno v:
The Journal of dermatology. 43(1)
We performed a gene expression study to explore whether expression levels of LBH contribute to the pathogenesis of systemic lupus erythematosus (SLE) and are associated with the genome-wide association study-identified SNP (rs7579944 and rs906868) an