Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Jian'an Luan"'
Autor:
Carl A. Melbourne, Caroline Hayward, Stefan Karrasch, Dirk Keidel, Katherine A. Fawcett, Susan M. Ring, Yohan Bossé, Carol A. Wang, Ben Michael Brumpton, Claudia Langenberg, Peter K. Joshi, Ke Hao, Igor Rudan, David J. Porteous, Don D. Sin, Raquel Granell, Blair H. Smith, Jian'an Luan, Kristian Hveem, Sarah E. Harris, Sandosh Padmanabhan, Archie Campbell, Sebastian May-Wilson, Veronique Vitart, Nicola Pirastu, Arnulf Langhammer, Craig E. Pennell, John M. Starr, Stefan Weiss, Karina Patasova, Nicholas J. Wareham, James F. Wilson, Deborah Jarvis, Tim D. Spector, Nick Shrine, David P. Strachan, Martin D. Tobin, Beate Stubbe, David M. Evans, Kirsi H. Pietiläinen, Mangino Massimo, Ian P. Hall, Graham L. Hall, Jaakko Kaprio, Ralf Ewert, Rachel E. Foong, Claudia Flexeder, Louise V. Wain, Ma'en Obeidat, Cristen J. Willer, Leo-Pekka Lyytikäinen, Olli T. Raitakari, John Henderson, Konstantin Strauch, Marta R Moksnes, Cosetta Minelli, Nicole Probst-Hensch, Pirro G. Hysi, Anna L. Guyatt, Henry Völzke, Thomas Meitinger, Peter D. Sly, Ozren Polasek, Anne Richmond, Mika Kähönen, Maarten van den Berge, Medea Imboden, Thibaud Boutin, Lucija Klaric, Laura Portas, Terho Lehtimäki, Ian J. Deary, Taina Rantanen, Catherine John, Teemu Palviainen
Publikováno v:
Fawcett, K, Granell, R & Wain, L V 2021, ' Variants associated with HHIP expression have sex-differential effects on lung function ', Wellcome Open Research, vol. 5, pp. 1-20 . https://doi.org/10.12688/WELLCOMEOPENRES.15846.2
Wellcome open research, 5:111
Wellcome Open Research
Fawcett, K A, Obeidat, M, Melbourne, C, Shrine, N, Guyatt, A L, John, C, Luan, J, Richmond, A, Moksnes, M R, Granell, R, Weiss, S, Imboden, M, May-Wilson, S, Hysi, P, Boutin, T S, Portas, L, Flexeder, C, Harris, S E, Wang, C A, Lyytikäinen, L P, Palviainen, T, Foong, R E, Keidel, D, Minelli, C, Langenberg, C, Bossé, Y, Berge, M V D, Sin, D D, Hao, K, Campbell, A, Porteous, D, Padmanabhan, S, Smith, B H, Evans, D M, Ring, S, Langhammer, A, Hveem, K, Willer, C, Ewert, R, Stubbe, B, Pirastu, N, Klaric, L, Joshi, P K, Patasova, K, Massimo, M, Polasek, O, Starr, J M, Karrasch, S, Strauch, K, Meitinger, T, Rudan, I, Rantanen, T, Pietiläinen, K, Kähönen, M, Raitakari, O T, Hall, G L, Sly, P D, Pennell, C E, Kaprio, J, Lehtimäki, T, Vitart, V, Deary, I J, Jarvis, D, Wilson, J F, Spector, T, Probst-Hensch, N, Wareham, N J, Völzke, H, Henderson, J, Strachan, D P, Brumpton, B M, Hayward, C, Hall, I P, Tobin, M D & Wain, L V 2021, ' Variants associated with HHIP expression have sexdifferential effects on lung function ', Wellcome Open Research, vol. 5, pp. 1-20 . https://doi.org/10.12688/WELLCOMEOPENRES.15846.2
Wellcome Open Res. 5:111 (2021)
Fawcett, K A, Obeidat, M, Melbourne, C, Shrine, N, Guyatt, A L, John, C, Luan, J, Richmond, A, Moksnes, M R, Granell, R, Weiss, S, Imboden, M, May-wilson, S, Hysi, P, Boutin, T S, Portas, L, Flexeder, C, Harris, S E, Wang, C A, Lyytikäinen, L, Palviainen, T, Foong, R E, Keidel, D, Minelli, C, Langenberg, C, Bossé, Y, Van Den Berge, M, Sin, D D, Hao, K, Campbell, A, Porteous, D, Padmanabhan, S, Smith, B H, Evans, D M, Ring, S, Langhammer, A, Hveem, K, Willer, C, Ewert, R, Stubbe, B, Pirastu, N, Klaric, L, Joshi, P K, Patasova, K, Massimo, M, Polasek, O, Starr, J M, Karrasch, S, Strauch, K, Meitinger, T, Rudan, I, Rantanen, T, Pietiläinen, K, Kähönen, M, Raitakari, O T, Hall, G L, Sly, P D, Pennell, C E, Kaprio, J, Lehtimäki, T, Vitart, V, Deary, I J, Jarvis, D, Wilson, J F, Spector, T, Probst-hensch, N, Wareham, N J, Völzke, H, Henderson, J, Strachan, D P, Brumpton, B M, Hayward, C, Hall, I P, Tobin, M D & Wain, L V 2021, ' Variants associated with HHIP expression have sex-differential effects on lung function ', Wellcome Open Research, vol. 5, pp. 111 . https://doi.org/10.12688/wellcomeopenres.15846.1
Wellcome open research, 5:111
Wellcome Open Research
Fawcett, K A, Obeidat, M, Melbourne, C, Shrine, N, Guyatt, A L, John, C, Luan, J, Richmond, A, Moksnes, M R, Granell, R, Weiss, S, Imboden, M, May-Wilson, S, Hysi, P, Boutin, T S, Portas, L, Flexeder, C, Harris, S E, Wang, C A, Lyytikäinen, L P, Palviainen, T, Foong, R E, Keidel, D, Minelli, C, Langenberg, C, Bossé, Y, Berge, M V D, Sin, D D, Hao, K, Campbell, A, Porteous, D, Padmanabhan, S, Smith, B H, Evans, D M, Ring, S, Langhammer, A, Hveem, K, Willer, C, Ewert, R, Stubbe, B, Pirastu, N, Klaric, L, Joshi, P K, Patasova, K, Massimo, M, Polasek, O, Starr, J M, Karrasch, S, Strauch, K, Meitinger, T, Rudan, I, Rantanen, T, Pietiläinen, K, Kähönen, M, Raitakari, O T, Hall, G L, Sly, P D, Pennell, C E, Kaprio, J, Lehtimäki, T, Vitart, V, Deary, I J, Jarvis, D, Wilson, J F, Spector, T, Probst-Hensch, N, Wareham, N J, Völzke, H, Henderson, J, Strachan, D P, Brumpton, B M, Hayward, C, Hall, I P, Tobin, M D & Wain, L V 2021, ' Variants associated with HHIP expression have sexdifferential effects on lung function ', Wellcome Open Research, vol. 5, pp. 1-20 . https://doi.org/10.12688/WELLCOMEOPENRES.15846.2
Wellcome Open Res. 5:111 (2021)
Fawcett, K A, Obeidat, M, Melbourne, C, Shrine, N, Guyatt, A L, John, C, Luan, J, Richmond, A, Moksnes, M R, Granell, R, Weiss, S, Imboden, M, May-wilson, S, Hysi, P, Boutin, T S, Portas, L, Flexeder, C, Harris, S E, Wang, C A, Lyytikäinen, L, Palviainen, T, Foong, R E, Keidel, D, Minelli, C, Langenberg, C, Bossé, Y, Van Den Berge, M, Sin, D D, Hao, K, Campbell, A, Porteous, D, Padmanabhan, S, Smith, B H, Evans, D M, Ring, S, Langhammer, A, Hveem, K, Willer, C, Ewert, R, Stubbe, B, Pirastu, N, Klaric, L, Joshi, P K, Patasova, K, Massimo, M, Polasek, O, Starr, J M, Karrasch, S, Strauch, K, Meitinger, T, Rudan, I, Rantanen, T, Pietiläinen, K, Kähönen, M, Raitakari, O T, Hall, G L, Sly, P D, Pennell, C E, Kaprio, J, Lehtimäki, T, Vitart, V, Deary, I J, Jarvis, D, Wilson, J F, Spector, T, Probst-hensch, N, Wareham, N J, Völzke, H, Henderson, J, Strachan, D P, Brumpton, B M, Hayward, C, Hall, I P, Tobin, M D & Wain, L V 2021, ' Variants associated with HHIP expression have sex-differential effects on lung function ', Wellcome Open Research, vol. 5, pp. 111 . https://doi.org/10.12688/wellcomeopenres.15846.1
Background: Lung function is highly heritable and differs between the sexes throughout life. However, little is known about sex-differential genetic effects on lung function. We aimed to conduct the first genome-wide genotype-by-sex interaction study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::312f5db945545c66e6f18c62faf6290c
https://research-information.bris.ac.uk/ws/files/287782046/3fa30dd5_3d84_4cd9_880c_57cb63dda7c6_15846_katherine_fawcett_v2.pdf
https://research-information.bris.ac.uk/ws/files/287782046/3fa30dd5_3d84_4cd9_880c_57cb63dda7c6_15846_katherine_fawcett_v2.pdf
Autor:
Tuomas O. Kilpeläinen, Jacqueline S. L. Kloth, Nam H. Cho, Peter Vollenweider, Georg Homuth, Unnur Thorsteinsdottir, Nicole C. Wright, Wen-Chi Chou, Yongmei Liu, Kari Stefansson, Kim M. Huffman, Ida Malkin, Andrew P. Morris, Robert Luben, Shad B. Smith, Lei Yu, Joel Eriksson, Aarno Palotie, Veikko Salomaa, Michael J. Econs, Liesbeth Vandenput, Elizabeth A. Streeten, Albert Hofman, Elisabeth Widen, Emmi Tikkanen, Braxton D. Mitchell, Natasja M. van Schoor, Caroline Hayward, Liisa Byberg, Joanne M. Jordan, Bruce M. Psaty, Elisabeth Steinhagen-Thiessen, Magnus Karlsson, Harry Campbell, John C. Chambers, Fernando Rivadeneira, Johan G. Eriksson, Jari Lahti, Reiner Biffar, James F. Wilson, Luda Diatchenko, Jerome I. Rotter, Eric S. Orwoll, Launer J. Lenore, Cornelia M. van Duijn, Frances M K Williams, Munro Peacock, David A. Bennett, Annette Peters, Ali A. Aghdassi, Gudny Eiriksdottir, Weihua Zhang, Östen Ljunggren, Daniel L. Koller, Nicole Soranzo, Patricia A. Thompson, Jane A. Cauley, John A Robbins, Mattias Lorentzon, Igor Rudan, Thomas Illig, Claes Ohlsson, Ilja Demuth, Zoltán Kutalik, Aron S. Buchman, Jian'an Luan, Erik Ingelsson, Natalia Campos-Obando, Karol Estrada, Chan Soo Shin, Lisette Stolk, Gudmar Thorleifsson, Douglas P. Kiel, Michael N. Weedon, Lars Bertram, Fiona E. McGuigan, Ben A. Oostra, Thomas Meitinger, Mary F. Feitosa, Christian Gieger, Jean Wactawski-Wende, Yanhua Zhou, Serkalem Demissie, Najaf Amin, Anke W. Enneman, Håkan Melhus, Stuart H. Ralston, Johanna Kuusisto, Markku Laakso, Mark Walker, Tim D. Spector, Karl Michaëlsson, John-Olov Jansson, Richard L. Prince, Leif Mosekilde, Sabine Schipf, Carolina Medina-Gomez, Antti Jula, Carrie M. Nielson, Bente L. Langdahl, André G. Uitterlinden, Kay-Tee Khaw, Ruth J. F. Loos, Kristina Åkesson, Albert V. Smith, Tamara B. Harris, Cynthia A. Thomson, Karin M. A. Swart, Unnur Styrkarsdottir, Yi-Hsiang Hsu, Anne B. Newman, Murielle Bochud, M. Carola Zillikens, Alena Stančáková, Markus M. Lerch, Maria Nethander, Gregory Livshits, Dawn Waterworth, Christina M. Lill, Henry Völzke, Steven R. Cummings, Lise B. Husted, Cecilia M. Lindgren, Jaspal S. Kooner, Joshua R. Lewis, Katri Räikkönen, Linda Broer, Inês Barroso, Teemu Kuulasmaa, Jeffery R. O'Connell, Harald Grallert, William E. Kraus, Nicholas J. Wareham, Lars Lind, David Karasik, H-Erich Wichmann, Gregory J. Tranah, Mao Fu, Toby Johnson, Samuli Ripatti, Dan Mellström, Suzanne Satterfield, Jing Hua Zhao, Hyung Jin Choi, Vilmundur Gudnason, Lisette C. P. G. M. de Groot, Stephen B. Kritchevsky, Zhao Chen, Norman Klopp, Till Ittermann, Daniel S. Evans, Phillip L. De Jager, Ingrid B. Borecki, Laura M. Yerges-Armstrong, Peggy M. Cawthon, Thomas Lang, Markus Perola
Publikováno v:
The American Journal of Clinical Nutrition
American Journal of Clinical Nutrition 109 (2019) 2
American Journal of Clinical Nutrition, 109(2), 276-287. American Society for Nutrition
American Journal of Clinical Nutrition, 276-287. American Society for Nutrition
STARTPAGE=276;ENDPAGE=287;ISSN=0002-9165;TITLE=American Journal of Clinical Nutrition
The American journal of clinical nutrition
Karasik, D, Zillikens, M C, Hsu, Y-H, Aghdassi, A, Akesson, K, Amin, N, Barroso, I, Bennett, D A, Bertram, L, Bochud, M, Borecki, I B, Broer, L, Buchman, A S, Byberg, L, Campbell, H, Campos-Obando, N, Cauley, J A, Cawthon, P M, Chambers, J C, Chen, Z, Cho, N H, Choi, H J, Chou, W-C, Cummings, S R, de Groot, L C P G M, De Jager, P L, Demuth, I, Diatchenko, L, Econs, M J, Eiriksdottir, G, Enneman, A W, Eriksson, J, Eriksson, J G, Estrada, K, Evans, D S, Feitosa, M F, Fu, M, Gieger, C, Grallert, H, Gudnason, V, Lenore, L J, Hayward, C, Hofman, A, Homuth, G, Huffman, K M, Husted, L B, Illig, T, Ingelsson, E, Ittermann, T, Jansson, J-O, Johnson, T, Biffar, R, Jordan, J M, Jula, A, Karlsson, M, Khaw, K-T, Kilpeläinen, T O, Klopp, N, Kloth, J S L, Koller, D L, Kooner, J S, Kraus, W E, Kritchevsky, S, Kutalik, Z, Kuulasmaa, T, Kuusisto, J, Laakso, M, Lahti, J, Lang, T, Langdahl, B L, Lerch, M M, Lewis, J R, Lill, C, Lind, L, Lindgren, C, Liu, Y, Livshits, G, Ljunggren, Ö, Loos, R J F, Lorentzon, M, Luan, J, Luben, R N, Malkin, I, McGuigan, F E, Medina-Gomez, C, Meitinger, T, Melhus, H, Mellström, D, Michaëlsson, K, Mitchell, B D, Morris, A P, Mosekilde, L, Nethander, M, Newman, A B, O'Connell, J R, Oostra, B A, Orwoll, E S, Palotie, A, Peacock, M, Perola, M, Peters, A, Prince, R L, Psaty, B M, Räikkönen, K, Ralston, S H, Ripatti, S, Rivadeneira, F, Robbins, J A, Rotter, J I, Rudan, I, Salomaa, V, Satterfield, S, Schipf, S, Shin, C S, Smith, A V, Smith, S B, Soranzo, N, Spector, T D, Stancáková, A, Stefansson, K, Steinhagen-Thiessen, E, Stolk, L, Streeten, E A, Styrkarsdottir, U, Swart, K M A, Thompson, P, Thomson, C A, Thorleifsson, G, Thorsteinsdottir, U, Tikkanen, E, Tranah, G J, Uitterlinden, A G, van Duijn, C M, van Schoor, N M, Vandenput, L, Vollenweider, P, Völzke, H, Wactawski-Wende, J, Walker, M, J Wareham, N, Waterworth, D, Weedon, M N, Wichmann, H-E, Widen, E, Williams, F M K, Wilson, J F, Wright, N C, Yerges-Armstrong, L M, Yu, L, Zhang, W, Zhao, J H, Zhou, Y, Nielson, C M, Harris, T B, Demissie, S, Kiel, D P & Ohlsson, C 2019, ' Disentangling the genetics of lean mass ', The American Journal of Clinical Nutrition, vol. 109, no. 2, pp. 276-287 . https://doi.org/10.1093/ajcn/nqy272
Karasik, D, Zillikens, M C, Hsu, Y H, Aghdassi, A, Akesson, K, Amin, N, Barroso, I, Bennett, D A, Swart, KMA, Bertram, L, Bochud, M, Borecki, I B, Broer, L, Buchman, A S, Byberg, L, Campbell, H, Campos-Obando, N, Cauley, J A, Cawthon, P M, Chambers, J C, Chou, W C, Demuth, I, DIatchenko, L, Econs, M J, Eiriksdottir, G, Enneman, A W, Eriksson, J, Eriksson, J G, Chen, Z, Cho, N H, Choi, H J, Cummings, S R, de Groot, L C P G M, de Jager, P L, Estrada, K, Evans, D S, Feitosa, M F, Fu, M, Gieger, C, Grallert, H, Gudnason, V, Lenore, L J, Hayward, C, Hofman, A, Homuth, G, Huffman, K M, Husted, L B, Illig, T, Ingelsson, E, Ittermann, T, Jansson, J O, Johnson, T, Biffar, R, Jordan, J M, Jula, A, Karlsson, M, Khaw, K T, Kilpeläinen, T O, Klopp, N, Kloth, J S L, Koller, D L, Kooner, J S, Kraus, W E, Kritchevsky, S, Kutalik, Z, Kuulasmaa, T, Kuusisto, J, Laakso, M, Lahti, J, Lang, T, Langdahl, B L, Lerch, M M, Lewis, J R, Lill, C M, Lind, L, Lindgren, C M, Liu, Y, Livshits, G, Ljunggren, O, Loos, R J F, Lorentzon, M, Luan, J, Luben, R N, Malkin, I, McGuigan, F E, Medina-Gómez, C, Meitinger, T, Melhus, H, Mellstrom, D, Michaelsson, K, Mitchell, B D, Morris, A P, Mosekilde, L, Nethander, M, Newman, A B, O'Connell, J R, Oostra, B A, Orwoll, E S, Palotie, A, Peacock, M, Perola, M, Peters, A, Prince, R L, Psaty, B M, Raikkonen, K, Ralston, S H, Ripatti, S, Rivadeneira, F, Robbins, J A, Rotter, J I, Rudan, I, Salomaa, V, Satterfield, S, Schipf, S, Shin, C S, Smith, A V, Smith, S, Soranzo, N, Spector, T D, Stancakova, A, Stefansson, K, Steinhagen-Thiessen, E, Stolk, L, Streeten, E A, Styrkarsdottir, U, Thompson, P, Thomson, C A, Thorleifsson, G, Thorsteinsdottir, U, Tikkanen, E, Tranah, G J, Uitterlinden, A G, van Duijn, C M, van Schoor, NM, Vandenput, L, Vollenweider, P, Volzke, H, Wactawski-Wende, J, Walker, M, J Wareham, N, Waterworth, D, Weedon, M N, Wichmann, H E, Widen, E, Williams, F M K, Wilson, J F, Wright, N C, Yerges-Armstrong, L M, Yu, L, Zhang, W, Zhao, J H, Zhou, Y, Nielson, C M, Harris, T B, Demissie, S, Kiel, D P & Ohlsson, C 2019, ' Disentangling the genetics of lean mass ', American Journal of Clinical Nutrition, pp. 276-287 .
Karasik, D, Zillikens, M C, Hsu, Y-H, Aghdassi, A, Akesson, K, Amin, N, Barroso, I, Bennett, D A, Bertram, L, Bochud, M, Borecki, I B, Broer, L, Buchman, A S, Byberg, L, Campbell, H, Campos-Obando, N, Cauley, J A, Cawthon, P M, Chambers, J C, Chen, Z, Cho, N H, Choi, H J, Chou, W-C, Cummings, S R, de Groot, L C P G M, De Jager, P L, Demuth, I, Diatchenko, L, Econs, M J, Eiriksdottir, G, Enneman, A W, Eriksson, J, Eriksson, J G, Estrada, K, Evans, D S, Feitosa, M F, Fu, M, Gieger, C, Grallert, H, Gudnason, V, Lenore, L J, Hayward, C, Hofman, A, Homuth, G, Huffman, K M, Husted, L B, Illig, T, Ingelsson, E, Ittermann, T, Jansson, J-O, Johnson, T, Biffar, R, Jordan, J M, Jula, A, Karlsson, M, Khaw, K-T, Kilpeläinen, T O, Klopp, N, Kloth, J S L, Koller, D L, Kooner, J S, Kraus, W E, Kritchevsky, S, Kutalik, Z, Kuulasmaa, T, Kuusisto, J, Laakso, M, Lahti, J, Lang, T, Langdahl, B L, Lerch, M M, Lewis, J R, Lill, C, Lind, L, Lindgren, C, Liu, Y, Livshits, G, Ljunggren, Ö, Loos, R J F, Lorentzon, M, Luan, J, Luben, R N, Malkin, I, McGuigan, F E, Medina-Gomez, C, Meitinger, T, Melhus, H, Mellström, D, Michaëlsson, K, Mitchell, B D, Morris, A P, Mosekilde, L, Nethander, M, Newman, A B, O'Connell, J R, Oostra, B A, Orwoll, E S, Palotie, A, Peacock, M, Perola, M, Peters, A, Prince, R L, Psaty, B M, Räikkönen, K, Ralston, S H, Ripatti, S, Rivadeneira, F, Robbins, J A, Rotter, J I, Rudan, I, Salomaa, V, Satterfield, S, Schipf, S, Shin, C S, Smith, A V, Smith, S B, Soranzo, N, Spector, T D, Stancáková, A, Stefansson, K, Steinhagen-Thiessen, E, Stolk, L, Streeten, E A, Styrkarsdottir, U, Swart, K M A, Thompson, P, Thomson, C A, Thorleifsson, G, Thorsteinsdottir, U, Tikkanen, E, Tranah, G J, Uitterlinden, A G, van Duijn, C M, van Schoor, N M, Vandenput, L, Vollenweider, P, Völzke, H, Wactawski-Wende, J, Walker, M, J Wareham, N, Waterworth, D, Weedon, M N, Wichmann, H-E, Widen, E, Williams, F M K, Wilson, J F, Wright, N C, Yerges-Armstrong, L M, Yu, L, Zhang, W, Zhao, J H, Zhou, Y, Nielson, C M, Harris, T B, Demissie, S, Kiel, D P & Ohlsson, C 2019, ' Disentangling the genetics of lean mass ', The American Journal of Clinical Nutrition (AJCN) . https://doi.org/10.1093/ajcn/nqy272
Karasik, D, Zillikens, M C, Hsu, Y-H, Aghdassi, A, Akesson, K, Amin, N, Barroso, I, Bennett, D A, Bertram, L, Bochud, M, Borecki, I B, Broer, L, Buchman, A S, Byberg, L, Campbell, H, Campos-Obando, N, Cauley, J A, Cawthon, P M, Chambers, J C, Chen, Z, Cho, N H, Choi, H J, Chou, W-C, Cummings, S R, de Groot, L C P G M, De Jager, P L, Demuth, I, Diatchenko, L, Econs, M J, Eiriksdottir, G, Enneman, A W, Eriksson, J, Eriksson, J G, Estrada, K, Evans, D S, Feitosa, M F, Fu, M, Gieger, C, Grallert, H, Gudnason, V, Lenore, L J, Hayward, C, Hofman, A, Homuth, G, Huffman, K M, Husted, L B, Illig, T, Ingelsson, E, Ittermann, T, Jansson, J-O, Johnson, T, Biffar, R, Jordan, J M, Jula, A, Karlsson, M, Khaw, K-T, Kilpeläinen, T O, Klopp, N, Kloth, J S L, Koller, D L, Kooner, J S, Kraus, W E, Kritchevsky, S, Kutalik, Z, Kuulasmaa, T, Kuusisto, J, Laakso, M, Lahti, J, Lang, T, Langdahl, B L, Lerch, M M, Lewis, J R, Lill, C, Lind, L, Lindgren, C, Liu, Y, Livshits, G, Ljunggren, Ö, Loos, R J F, Lorentzon, M, Luan, J, Luben, R N, Malkin, I, McGuigan, F E, Medina-Gomez, C, Meitinger, T, Melhus, H, Mellström, D, Michaëlsson, K, Mitchell, B D, Morris, A P, Mosekilde, L, Nethander, M, Newman, A B, O'Connell, J R, Oostra, B A, Orwoll, E S, Palotie, A, Peacock, M, Perola, M, Peters, A, Prince, R L, Psaty, B M, Räikkönen, K, Ralston, S H, Ripatti, S, Rivadeneira, F, Robbins, J A, Rotter, J I, Rudan, I, Salomaa, V, Satterfield, S, Schipf, S, Shin, C S, Smith, A V, Smith, S B, Soranzo, N, Spector, T D, Stancáková, A, Stefansson, K, Steinhagen-Thiessen, E, Stolk, L, Streeten, E A, Styrkarsdottir, U, Swart, K M A, Thompson, P, Thomson, C A, Thorleifsson, G, Thorsteinsdottir, U, Tikkanen, E, Tranah, G J, Uitterlinden, A G, van Duijn, C M, van Schoor, N M, Vandenput, L, Vollenweider, P, Völzke, H, Wactawski-Wende, J, Walker, M, J Wareham, N, Waterworth, D, Weedon, M N, Wichmann, H-E, Widen, E, Williams, F M K, Wilson, J F, Wright, N C, Yerges-Armstrong, L M, Yu, L, Zhang, W, Zhao, J H, Zhou, Y, Nielson, C M, Harris, T B, Demissie, S, Kiel, D P & Ohlsson, C 2019, ' Disentangling the genetics of lean mass ', The American journal of clinical nutrition, vol. 109, no. 2, pp. 276-287 . https://doi.org/10.1093/ajcn/nqy272
American Journal of Clinical Nutrition, 109(2), 276-278
American Journal of Clinical Nutrition 109 (2019) 2
American Journal of Clinical Nutrition, 109(2), 276-287. American Society for Nutrition
American Journal of Clinical Nutrition, 276-287. American Society for Nutrition
STARTPAGE=276;ENDPAGE=287;ISSN=0002-9165;TITLE=American Journal of Clinical Nutrition
The American journal of clinical nutrition
Karasik, D, Zillikens, M C, Hsu, Y-H, Aghdassi, A, Akesson, K, Amin, N, Barroso, I, Bennett, D A, Bertram, L, Bochud, M, Borecki, I B, Broer, L, Buchman, A S, Byberg, L, Campbell, H, Campos-Obando, N, Cauley, J A, Cawthon, P M, Chambers, J C, Chen, Z, Cho, N H, Choi, H J, Chou, W-C, Cummings, S R, de Groot, L C P G M, De Jager, P L, Demuth, I, Diatchenko, L, Econs, M J, Eiriksdottir, G, Enneman, A W, Eriksson, J, Eriksson, J G, Estrada, K, Evans, D S, Feitosa, M F, Fu, M, Gieger, C, Grallert, H, Gudnason, V, Lenore, L J, Hayward, C, Hofman, A, Homuth, G, Huffman, K M, Husted, L B, Illig, T, Ingelsson, E, Ittermann, T, Jansson, J-O, Johnson, T, Biffar, R, Jordan, J M, Jula, A, Karlsson, M, Khaw, K-T, Kilpeläinen, T O, Klopp, N, Kloth, J S L, Koller, D L, Kooner, J S, Kraus, W E, Kritchevsky, S, Kutalik, Z, Kuulasmaa, T, Kuusisto, J, Laakso, M, Lahti, J, Lang, T, Langdahl, B L, Lerch, M M, Lewis, J R, Lill, C, Lind, L, Lindgren, C, Liu, Y, Livshits, G, Ljunggren, Ö, Loos, R J F, Lorentzon, M, Luan, J, Luben, R N, Malkin, I, McGuigan, F E, Medina-Gomez, C, Meitinger, T, Melhus, H, Mellström, D, Michaëlsson, K, Mitchell, B D, Morris, A P, Mosekilde, L, Nethander, M, Newman, A B, O'Connell, J R, Oostra, B A, Orwoll, E S, Palotie, A, Peacock, M, Perola, M, Peters, A, Prince, R L, Psaty, B M, Räikkönen, K, Ralston, S H, Ripatti, S, Rivadeneira, F, Robbins, J A, Rotter, J I, Rudan, I, Salomaa, V, Satterfield, S, Schipf, S, Shin, C S, Smith, A V, Smith, S B, Soranzo, N, Spector, T D, Stancáková, A, Stefansson, K, Steinhagen-Thiessen, E, Stolk, L, Streeten, E A, Styrkarsdottir, U, Swart, K M A, Thompson, P, Thomson, C A, Thorleifsson, G, Thorsteinsdottir, U, Tikkanen, E, Tranah, G J, Uitterlinden, A G, van Duijn, C M, van Schoor, N M, Vandenput, L, Vollenweider, P, Völzke, H, Wactawski-Wende, J, Walker, M, J Wareham, N, Waterworth, D, Weedon, M N, Wichmann, H-E, Widen, E, Williams, F M K, Wilson, J F, Wright, N C, Yerges-Armstrong, L M, Yu, L, Zhang, W, Zhao, J H, Zhou, Y, Nielson, C M, Harris, T B, Demissie, S, Kiel, D P & Ohlsson, C 2019, ' Disentangling the genetics of lean mass ', The American Journal of Clinical Nutrition, vol. 109, no. 2, pp. 276-287 . https://doi.org/10.1093/ajcn/nqy272
Karasik, D, Zillikens, M C, Hsu, Y H, Aghdassi, A, Akesson, K, Amin, N, Barroso, I, Bennett, D A, Swart, KMA, Bertram, L, Bochud, M, Borecki, I B, Broer, L, Buchman, A S, Byberg, L, Campbell, H, Campos-Obando, N, Cauley, J A, Cawthon, P M, Chambers, J C, Chou, W C, Demuth, I, DIatchenko, L, Econs, M J, Eiriksdottir, G, Enneman, A W, Eriksson, J, Eriksson, J G, Chen, Z, Cho, N H, Choi, H J, Cummings, S R, de Groot, L C P G M, de Jager, P L, Estrada, K, Evans, D S, Feitosa, M F, Fu, M, Gieger, C, Grallert, H, Gudnason, V, Lenore, L J, Hayward, C, Hofman, A, Homuth, G, Huffman, K M, Husted, L B, Illig, T, Ingelsson, E, Ittermann, T, Jansson, J O, Johnson, T, Biffar, R, Jordan, J M, Jula, A, Karlsson, M, Khaw, K T, Kilpeläinen, T O, Klopp, N, Kloth, J S L, Koller, D L, Kooner, J S, Kraus, W E, Kritchevsky, S, Kutalik, Z, Kuulasmaa, T, Kuusisto, J, Laakso, M, Lahti, J, Lang, T, Langdahl, B L, Lerch, M M, Lewis, J R, Lill, C M, Lind, L, Lindgren, C M, Liu, Y, Livshits, G, Ljunggren, O, Loos, R J F, Lorentzon, M, Luan, J, Luben, R N, Malkin, I, McGuigan, F E, Medina-Gómez, C, Meitinger, T, Melhus, H, Mellstrom, D, Michaelsson, K, Mitchell, B D, Morris, A P, Mosekilde, L, Nethander, M, Newman, A B, O'Connell, J R, Oostra, B A, Orwoll, E S, Palotie, A, Peacock, M, Perola, M, Peters, A, Prince, R L, Psaty, B M, Raikkonen, K, Ralston, S H, Ripatti, S, Rivadeneira, F, Robbins, J A, Rotter, J I, Rudan, I, Salomaa, V, Satterfield, S, Schipf, S, Shin, C S, Smith, A V, Smith, S, Soranzo, N, Spector, T D, Stancakova, A, Stefansson, K, Steinhagen-Thiessen, E, Stolk, L, Streeten, E A, Styrkarsdottir, U, Thompson, P, Thomson, C A, Thorleifsson, G, Thorsteinsdottir, U, Tikkanen, E, Tranah, G J, Uitterlinden, A G, van Duijn, C M, van Schoor, NM, Vandenput, L, Vollenweider, P, Volzke, H, Wactawski-Wende, J, Walker, M, J Wareham, N, Waterworth, D, Weedon, M N, Wichmann, H E, Widen, E, Williams, F M K, Wilson, J F, Wright, N C, Yerges-Armstrong, L M, Yu, L, Zhang, W, Zhao, J H, Zhou, Y, Nielson, C M, Harris, T B, Demissie, S, Kiel, D P & Ohlsson, C 2019, ' Disentangling the genetics of lean mass ', American Journal of Clinical Nutrition, pp. 276-287 .
Karasik, D, Zillikens, M C, Hsu, Y-H, Aghdassi, A, Akesson, K, Amin, N, Barroso, I, Bennett, D A, Bertram, L, Bochud, M, Borecki, I B, Broer, L, Buchman, A S, Byberg, L, Campbell, H, Campos-Obando, N, Cauley, J A, Cawthon, P M, Chambers, J C, Chen, Z, Cho, N H, Choi, H J, Chou, W-C, Cummings, S R, de Groot, L C P G M, De Jager, P L, Demuth, I, Diatchenko, L, Econs, M J, Eiriksdottir, G, Enneman, A W, Eriksson, J, Eriksson, J G, Estrada, K, Evans, D S, Feitosa, M F, Fu, M, Gieger, C, Grallert, H, Gudnason, V, Lenore, L J, Hayward, C, Hofman, A, Homuth, G, Huffman, K M, Husted, L B, Illig, T, Ingelsson, E, Ittermann, T, Jansson, J-O, Johnson, T, Biffar, R, Jordan, J M, Jula, A, Karlsson, M, Khaw, K-T, Kilpeläinen, T O, Klopp, N, Kloth, J S L, Koller, D L, Kooner, J S, Kraus, W E, Kritchevsky, S, Kutalik, Z, Kuulasmaa, T, Kuusisto, J, Laakso, M, Lahti, J, Lang, T, Langdahl, B L, Lerch, M M, Lewis, J R, Lill, C, Lind, L, Lindgren, C, Liu, Y, Livshits, G, Ljunggren, Ö, Loos, R J F, Lorentzon, M, Luan, J, Luben, R N, Malkin, I, McGuigan, F E, Medina-Gomez, C, Meitinger, T, Melhus, H, Mellström, D, Michaëlsson, K, Mitchell, B D, Morris, A P, Mosekilde, L, Nethander, M, Newman, A B, O'Connell, J R, Oostra, B A, Orwoll, E S, Palotie, A, Peacock, M, Perola, M, Peters, A, Prince, R L, Psaty, B M, Räikkönen, K, Ralston, S H, Ripatti, S, Rivadeneira, F, Robbins, J A, Rotter, J I, Rudan, I, Salomaa, V, Satterfield, S, Schipf, S, Shin, C S, Smith, A V, Smith, S B, Soranzo, N, Spector, T D, Stancáková, A, Stefansson, K, Steinhagen-Thiessen, E, Stolk, L, Streeten, E A, Styrkarsdottir, U, Swart, K M A, Thompson, P, Thomson, C A, Thorleifsson, G, Thorsteinsdottir, U, Tikkanen, E, Tranah, G J, Uitterlinden, A G, van Duijn, C M, van Schoor, N M, Vandenput, L, Vollenweider, P, Völzke, H, Wactawski-Wende, J, Walker, M, J Wareham, N, Waterworth, D, Weedon, M N, Wichmann, H-E, Widen, E, Williams, F M K, Wilson, J F, Wright, N C, Yerges-Armstrong, L M, Yu, L, Zhang, W, Zhao, J H, Zhou, Y, Nielson, C M, Harris, T B, Demissie, S, Kiel, D P & Ohlsson, C 2019, ' Disentangling the genetics of lean mass ', The American Journal of Clinical Nutrition (AJCN) . https://doi.org/10.1093/ajcn/nqy272
Karasik, D, Zillikens, M C, Hsu, Y-H, Aghdassi, A, Akesson, K, Amin, N, Barroso, I, Bennett, D A, Bertram, L, Bochud, M, Borecki, I B, Broer, L, Buchman, A S, Byberg, L, Campbell, H, Campos-Obando, N, Cauley, J A, Cawthon, P M, Chambers, J C, Chen, Z, Cho, N H, Choi, H J, Chou, W-C, Cummings, S R, de Groot, L C P G M, De Jager, P L, Demuth, I, Diatchenko, L, Econs, M J, Eiriksdottir, G, Enneman, A W, Eriksson, J, Eriksson, J G, Estrada, K, Evans, D S, Feitosa, M F, Fu, M, Gieger, C, Grallert, H, Gudnason, V, Lenore, L J, Hayward, C, Hofman, A, Homuth, G, Huffman, K M, Husted, L B, Illig, T, Ingelsson, E, Ittermann, T, Jansson, J-O, Johnson, T, Biffar, R, Jordan, J M, Jula, A, Karlsson, M, Khaw, K-T, Kilpeläinen, T O, Klopp, N, Kloth, J S L, Koller, D L, Kooner, J S, Kraus, W E, Kritchevsky, S, Kutalik, Z, Kuulasmaa, T, Kuusisto, J, Laakso, M, Lahti, J, Lang, T, Langdahl, B L, Lerch, M M, Lewis, J R, Lill, C, Lind, L, Lindgren, C, Liu, Y, Livshits, G, Ljunggren, Ö, Loos, R J F, Lorentzon, M, Luan, J, Luben, R N, Malkin, I, McGuigan, F E, Medina-Gomez, C, Meitinger, T, Melhus, H, Mellström, D, Michaëlsson, K, Mitchell, B D, Morris, A P, Mosekilde, L, Nethander, M, Newman, A B, O'Connell, J R, Oostra, B A, Orwoll, E S, Palotie, A, Peacock, M, Perola, M, Peters, A, Prince, R L, Psaty, B M, Räikkönen, K, Ralston, S H, Ripatti, S, Rivadeneira, F, Robbins, J A, Rotter, J I, Rudan, I, Salomaa, V, Satterfield, S, Schipf, S, Shin, C S, Smith, A V, Smith, S B, Soranzo, N, Spector, T D, Stancáková, A, Stefansson, K, Steinhagen-Thiessen, E, Stolk, L, Streeten, E A, Styrkarsdottir, U, Swart, K M A, Thompson, P, Thomson, C A, Thorleifsson, G, Thorsteinsdottir, U, Tikkanen, E, Tranah, G J, Uitterlinden, A G, van Duijn, C M, van Schoor, N M, Vandenput, L, Vollenweider, P, Völzke, H, Wactawski-Wende, J, Walker, M, J Wareham, N, Waterworth, D, Weedon, M N, Wichmann, H-E, Widen, E, Williams, F M K, Wilson, J F, Wright, N C, Yerges-Armstrong, L M, Yu, L, Zhang, W, Zhao, J H, Zhou, Y, Nielson, C M, Harris, T B, Demissie, S, Kiel, D P & Ohlsson, C 2019, ' Disentangling the genetics of lean mass ', The American journal of clinical nutrition, vol. 109, no. 2, pp. 276-287 . https://doi.org/10.1093/ajcn/nqy272
American Journal of Clinical Nutrition, 109(2), 276-278
Background: Lean body mass (LM) plays an important role in mobility and metabolic function. We previously identified five loci associated with LM adjusted for fat mass in kilograms. Such an adjustment may reduce the power to identify genetic signals
Autor:
Peter M. Nilsson, Olov Rolandsson, Eleanor Wheeler, Nicholas J. Wareham, Nita G. Forouhi, Matthias B. Schulze, Kim Overvad, Claudia Langenberg, Nicola D. Kerrison, Pilar Amiano, Catalina Bonet, Mark I. McCarthy, Inês Barroso, Yvonne T. van der Schouw, Lina Cai, Giovanna Masala, José María Huerta, Eva Ardanaz, Anne Tjønneland, Miguel Rodríguez-Barranco, Panos Deloukas, Leif Groop, Guy Fagherazzi, Jian'an Luan, Valeria Pala, Elio Riboli, Carlotta Sacerdote, Rosario Tumino, Paul W. Franks, Annemieke M.W. Spijkerman, Stephen J. Sharp, Salvatore Panico, Rudolf Kaaks
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Cai, L, Wheeler, E, Kerrison, N D, Luan, J, Deloukas, P, Franks, P W, Amiano, P, Ardanaz, E, Bonet, C, Fagherazzi, G, Groop, L C, Kaaks, R, Huerta, J M, Masala, G, Nilsson, P M, Overvad, K, Pala, V, Panico, S, Rodriguez-Barranco, M, Rolandsson, O, Sacerdote, C, Schulze, M B, Spijkerman, A M W, Tjonneland, A, Tumino, R, van der Schouw, Y T, Sharp, S J, Forouhi, N G, Riboli, E, McCarthy, M I, Barroso, I, Langenberg, C & Wareham, N J 2020, ' Genome-wide association analysis of type 2 diabetes in the EPIC-InterAct study ', Scientific Data, vol. 7, no. 1, 393 . https://doi.org/10.1038/s41597-020-00716-7
Scientific Data, Vol 7, Iss 1, Pp 1-6 (2020)
Scientific Data
Universidad de Barcelona
Cai, L, Wheeler, E, Kerrison, N D, Luan, J, Deloukas, P, Franks, P W, Amiano, P, Ardanaz, E, Bonet, C, Fagherazzi, G, Groop, L C, Kaaks, R, Huerta, J M, Masala, G, Nilsson, P M, Overvad, K, Pala, V, Panico, S, Rodriguez-Barranco, M, Rolandsson, O, Sacerdote, C, Schulze, M B, Spijkerman, A M W, Tjonneland, A, Tumino, R, van der Schouw, Y T, Sharp, S J, Forouhi, N G, Riboli, E, McCarthy, M I, Barroso, I, Langenberg, C & Wareham, N J 2020, ' Genome-wide association analysis of type 2 diabetes in the EPIC-InterAct study ', Scientific Data, vol. 7, no. 1, 393 . https://doi.org/10.1038/s41597-020-00716-7
Scientific Data, Vol 7, Iss 1, Pp 1-6 (2020)
Scientific Data
Funder: European Union FP6 programme grant number LSHM_CT_2006_037197
Type 2 diabetes (T2D) is a global public health challenge. Whilst the advent of genome-wide association studies has identified >400 genetic variants associated with T2D, our u
Type 2 diabetes (T2D) is a global public health challenge. Whilst the advent of genome-wide association studies has identified >400 genetic variants associated with T2D, our u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4985a655922547ce12b17698f85f47ef
https://www.repository.cam.ac.uk/handle/1810/310439
https://www.repository.cam.ac.uk/handle/1810/310439
Autor:
Nita G. Forouhi, Kim Overvad, Ivonne Sluijs, Tammy Y.N. Tong, Christina C. Dahm, Kay-Tee Khaw, Thomas E. Gundersen, José María Huerta, Peter M. Nilsson, Miguel Rodríguez-Barranco, Nasser Laouali, Adam S. Butterworth, Giovanna Masala, Sara Grioni, Rosario Tumino, Anja Olsen, Stephen J. Sharp, Salvatore Panico, J. Ramón Quirós, Yvonne T. van der Schouw, Eleanor Wheeler, Rudolf Kaaks, Alicia K Heath, Eva Ardanaz, Felix R. Day, Eleni Sofianopoulou, Konstantinos K. Tsilidis, Luca A. Lotta, Nicholas J. Wareham, Douae El-Fatouhi, Claudia Langenberg, Heiner Boeing, Guy Fagherazzi, Paula Jakszyn, Olov Rolandsson, Rupal L. Shah, Mazda Jenab, Miren Dorronsoro, Ju-Sheng Zheng, Fumiaki Imamura, Isobel D. Stewart, Elio Riboli, Paul W. Franks, Louise Hansen, John Danesh, Carlotta Sacerdote, Jian'an Luan, Niki Dimou, Annemieke M.W. Spijkerman, Tilman Kühn
Publikováno v:
Zheng, J S, Luan, J, Sofianopoulou, E, Sharp, S J, Day, F R, Imamura, F, Gundersen, T E, Lotta, L A, Sluijs, I, Stewart, I D, Shah, R L, Van Der Schouw, Y T, Wheeler, E, Ardanaz, E, Boeing, H, Dorronsoro, M, Dahm, C C, Dimou, N, El-Fatouhi, D, Franks, P W, Fagherazzi, G, Grioni, S, Huerta, J M, Heath, A K, Hansen, L, Jenab, M, Jakszyn, P, Kaaks, R, Kühn, T, Khaw, K T, Laouali, N, Masala, G, Nilsson, P M, Overvad, K, Olsen, A, Panico, S, Ramón Quirós, J, Rolandsson, O, Rodríguez-Barranco, M, Sacerdote, C, Spijkerman, A M W, Tong, T Y N, Tumino, R, Tsilidis, K K, Danesh, J, Riboli, E, Butterworth, A S, Langenberg, C, Forouhi, N G & Wareham, N J 2020, ' The association between circulating 25-hydroxyvitamin D metabolites and type 2 diabetes in European populations : A meta-analysis and Mendelian randomisation analysis ', PLOS Medicine, vol. 17, no. 10, e1003394 . https://doi.org/10.1371/journal.pmed.1003394
Dipòsit Digital de la UB
Universidad de Barcelona
Zheng, J-S, Luan, J, Sofianopoulou, E, Sharp, S J, Day, F R, Imamura, F, Gundersen, T E, Lotta, L A, Sluijs, I, Stewart, I D, Shah, R L, van der Schouw, Y T, Wheeler, E, Ardanaz, E, Boeing, H, Dorronsoro, M, Dahm, C C, Dimou, N, El-Fatouhi, D, Franks, P W, Fagherazzi, G, Grioni, S, Huerta, J M, Heath, A K, Hansen, L, Jenab, M, Jakszyn, P, Kaaks, R, Kühn, T, Khaw, K-T, Laouali, N, Masala, G, Nilsson, P M, Overvad, K, Olsen, A, Panico, S, Quirós, J R, Rolandsson, O, Rodríguez-Barranco, M, Sacerdote, C, Spijkerman, A M W, Tong, T Y N, Tumino, R, Tsilidis, K K, Danesh, J, Riboli, E, Butterworth, A S, Langenberg, C, Forouhi, N G & Wareham, N J 2020, ' The association between circulating 25-hydroxyvitamin D metabolites and type 2 diabetes in European populations : A meta-analysis and Mendelian randomisation analysis ', PLOS Medicine, vol. 17, no. 10, e1003394 . https://doi.org/10.1371/journal.pmed.1003394
PLoS Medicine, Vol 17, Iss 10, p e1003394 (2020)
PLoS Medicine
Dipòsit Digital de la UB
Universidad de Barcelona
Zheng, J-S, Luan, J, Sofianopoulou, E, Sharp, S J, Day, F R, Imamura, F, Gundersen, T E, Lotta, L A, Sluijs, I, Stewart, I D, Shah, R L, van der Schouw, Y T, Wheeler, E, Ardanaz, E, Boeing, H, Dorronsoro, M, Dahm, C C, Dimou, N, El-Fatouhi, D, Franks, P W, Fagherazzi, G, Grioni, S, Huerta, J M, Heath, A K, Hansen, L, Jenab, M, Jakszyn, P, Kaaks, R, Kühn, T, Khaw, K-T, Laouali, N, Masala, G, Nilsson, P M, Overvad, K, Olsen, A, Panico, S, Quirós, J R, Rolandsson, O, Rodríguez-Barranco, M, Sacerdote, C, Spijkerman, A M W, Tong, T Y N, Tumino, R, Tsilidis, K K, Danesh, J, Riboli, E, Butterworth, A S, Langenberg, C, Forouhi, N G & Wareham, N J 2020, ' The association between circulating 25-hydroxyvitamin D metabolites and type 2 diabetes in European populations : A meta-analysis and Mendelian randomisation analysis ', PLOS Medicine, vol. 17, no. 10, e1003394 . https://doi.org/10.1371/journal.pmed.1003394
PLoS Medicine, Vol 17, Iss 10, p e1003394 (2020)
PLoS Medicine
Background Prior research suggested a differential association of 25-hydroxyvitamin D (25(OH)D) metabolites with type 2 diabetes (T2D), with total 25(OH)D and 25(OH)D3 inversely associated with T2D, but the epimeric form (C3-epi-25(OH)D3) positively
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::508aa9e8f2e7c541164672eda8d51948
http://hdl.handle.net/10029/624491
http://hdl.handle.net/10029/624491
Autor:
Fumiaki Imamura, George Davey Smith, Chanwook Lee, Nicholas J. Wareham, M. Arfan Ikram, George McMahon, Aysu Okbay, Frank J. A. van Rooij, Peter Bowers, Carson C. Chow, Patrick Turley, Ronald de Vlaming, Jian'an Luan, Oscar H. Franco, Trudy Voortman, Daniel J. Benjamin, André G. Uitterlinden, Casper A.P. Burik, Nita G. Forouhi, K. Paige Harden, Pauline M Emmett, Cornelius A. Rietveld, Juan R. González, Bruce H. R. Wolffenbuttel, Philipp Koellinger, Mark Alan Fontana, James J. Lee, David Cesarini, Harold Snieder, Kim Valeska Emilie Braun, Emma L Anderson, Jana V. van Vliet-Ostaptchouk, Peter J. van der Most, Richard Karlsson Linnér, Susan M. Ring, Claudia Langenberg, Tonũ Esko, Fernando Rivadeneira, Kaitlin H Wade, Jessica C. Kiefte-de Jong, Taulant Muka, Mohsen Ghanbari, S. Fleur W. Meddens
Publikováno v:
Molecular Psychiatry, 26, 2056-2069. NATURE PUBLISHING GROUP
the 23 and Me Research Team 2020, ' Genomic analysis of diet composition finds novel loci and associations with health and lifestyle ', Molecular Psychiatry, vol. 2020 . https://doi.org/10.1038/s41380-020-0697-5
Molecular Psychiatry. Nature Publishing Group
Molecular Psychiatry
23Andme Research Team, EPIC-InterAct Consortium & LifeLines Cohort Study 2020, ' Genomic analysis of diet composition finds novel loci and associations with health and lifestyle ', Molecular Psychiatry, vol. 26, no. 6, pp. 2056-2069 . https://doi.org/10.1038/s41380-020-0697-5
Molecular psychiatry, vol 26, iss 6
Molecular Psychiatry, 26. Nature Publishing Group
Molecular Psychiatry, 26(6), 2056-2069. Nature Publishing Group
the 23 and Me Research Team 2020, ' Genomic analysis of diet composition finds novel loci and associations with health and lifestyle ', Molecular Psychiatry, vol. 2020 . https://doi.org/10.1038/s41380-020-0697-5
Molecular Psychiatry. Nature Publishing Group
Molecular Psychiatry
23Andme Research Team, EPIC-InterAct Consortium & LifeLines Cohort Study 2020, ' Genomic analysis of diet composition finds novel loci and associations with health and lifestyle ', Molecular Psychiatry, vol. 26, no. 6, pp. 2056-2069 . https://doi.org/10.1038/s41380-020-0697-5
Molecular psychiatry, vol 26, iss 6
Molecular Psychiatry, 26. Nature Publishing Group
Molecular Psychiatry, 26(6), 2056-2069. Nature Publishing Group
We conducted genome-wide association studies (GWAS) of relative intake from the macronutrients fat, protein, carbohydrates, and sugar in over 235,000 individuals of European ancestries. We identified 21 unique, approximately independent lead SNPs. Fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99d8d05f37a3c2c398c885bc70c40da9
https://www.nature.com/articles/s41380-020-0697-5
https://www.nature.com/articles/s41380-020-0697-5
Autor:
Tom Dudding, Nicholas J. Timpson, Jian'an Luan, Ruth E. Mitchell, Vincenzo Forgetta, J. Brent Richards, Simon Haworth, Rupal L. Shah, Despoina Manousaki, Adil Harroud, Claudia Langenberg
Publikováno v:
Mitchell, R E, Dudding, T, Haworth, S, Timpson, N J, Manousaki, D, Harroud, A, Forgetta, V, Shah, R L, Luan, J, Langenberg, C & Richards, B 2020, ' Genome-wide Association Study for Vitamin D Levels Reveals 69 Independent Loci ', American Journal of Human Genetics, vol. 106, no. 3, pp. 327-337 . https://doi.org/10.1016/j.ajhg.2020.01.017
Am J Hum Genet
Am J Hum Genet
We aimed to increase our understanding of the genetic determinants of vitamin D levels by undertaking a large-scale genome-wide as- sociation study (GWAS) of serum 25 hydroxyvitamin D (25OHD). To do so, we used imputed genotypes from 401,460 white Br
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b7264596f063fe23bdf8c7f9039bd06
https://hdl.handle.net/1983/9b11e312-f1b8-4a2f-b0d7-b4011bfe9a48
https://hdl.handle.net/1983/9b11e312-f1b8-4a2f-b0d7-b4011bfe9a48
Autor:
Michael Boehnke, Anke R. Hammerschlag, Stavroula Kanoni, Nilesh J. Samani, Stefan Blankenberg, Arpana Agrawal, Ersin Yavas, Chris Hsu, Dominique Arveiler, Giovanni Veronesi, Sarah E. Harris, Guillaume Lettre, Leah Wetherill, Helen R. Warren, M Samuel, Manav Kapoor, Praveen Surendran, Mengzhen Liu, Massimo Mangino, Abdulla Al Shafi Majumder, Chiara Batini, Jeff Haessler, Anton J. M. De Craen, Matt McGue, Laura J. Bierut, Yi Ling Chou, Markku Laakso, Ian J. Deary, Rebecca Rohde, Nhung Le, David Schlessinger, J. Dylan Weissenkampen, Claudia Langenberg, Tim D. Spector, Paul W. Franks, John P. Rice, Philippe M. Frossard, Hanieh Yaghootkar, Janie Corley, Frank Kee, J. Wouter Jukema, Pim van der Harst, Dermot F. Reily, Jenny Chang-Claude, Nicholas G. Martin, Tatiana Foroud, Sune F. Nielsen, Charles Kooperberg, Rudolf A. de Boer, Francesco Cucca, Paul D.P. Pharoah, Alex P. Reiner, Daniel R. Barnes, Anders Mälarstig, Jonathan Marten, Henry Völzke, Yu Jiang, Jukka Kontto, J Danesh, Antonis C. Antoniou, Andrew C. Heath, Nicholas J. Wareham, Joanna M. M. Howson, Alison Goate, Olov Rolandsson, Frida Renström, Chu Chen, Vinicius Tragante, Matt J. Neville, Kathleen Stirrups, Clemens Baumbach, Colin N. A. Palmer, Adam S. Butterworth, William G. Iacono, Naveed Sattar, Ian P. Hall, Daniel O. Stram, Giorgio Pistis, Jan-Håkan Jansson, Jaakko Kaprio, David R. Weir, David P. Strachan, Martin D. Tobin, Folkert W. Asselbergs, John M. Starr, Stefan Weiss, Thomas F. Vogt, Riccardo E. Marioni, Maarten Hoek, Jessica Tyrrell, Hilary A. Tindle, Alison M. Dunning, Anu Loukola, Joe Dennis, Victoria E. Jackson, Louise V. Wain, Eleftheria Zeggini, Weihua Zhang, Yaming Shao, Kari Kuulasmaa, Elisabeth Altmaier, Jean-Claude Tardif, Jian Gong, A. Mesut Erzurumluoglu, Andries R. van der Leij, Kari E. North, Anna F. Dominiczak, Martina Müller-Nurasyid, Scott I. Vrieze, Sarah Bertelsen, Markus Perola, Evangelos Evangelou, Chris J. Packard, Gonçalo R. Abecasis, Robert A. Scott, S. Trompet, Jennifer A. Smith, H. Steven Scholte, Timothy M. Frayling, Danielle Posthuma, Ian Ford, Douglas F. Easton, Børge Grønne Nordestgaard, Michiel L. Bots, Charles B. Eaton, Sharon L.R. Kardia, Dewan S. Alam, Xiaowei Zhan, Sean P. David, Maria Uria-Nickelsen, Dongbing Lai, Ilonca Vaartjes, Mark J. Caulfield, Valérie Turcot, Jean Ferrières, Emanuele Di Angelantonio, Robin Young, Pamela A. F. Madden, Tibor V. Varga, Asif Rasheed, Peter van der Meer, Dajiang J. Liu, Ioanna Tachmazidou, Panos Deloukas, Danish Saleheen, Evelin Mihailov, Caroline Hayward, Patricia B. Munroe, Beenish Qaiser, Jessica D. Faul, John C. Chambers, Matthias Nauck, Niek Verweij, Jordan M. Hughey, Christopher A. Haiman, Hans J. Grabe, Muriel Caslake, Saima Afaq, Jaspal S. Kooner, Tinca J. C. Polderman, Philippe Amouyel, Wei Zhao, Göran Hallmans, Andres Metspalu, Jarmo Virtamo, Carl A. Melbourne, Kaixin Zhou, Christiaan de Leeuw, Peter S. Sever, Eirini Marouli, Neil Poulter, Rajiv Chowdhury, Jian'an Luan, Deborah J. Thompson, F Karpe, Kyriaki Michailidou, David M. Brazel, Heather M. Stringham
Publikováno v:
Biological Psychiatry, 85(11), 946-955. Elsevier
Biological Psychiatry, 85(11), 946-955. Elsevier USA
Biological Psychiatry, 85(11), 946-955. ELSEVIER SCIENCE INC
Brazel, D M, Jiang, Y, Hughey, J M, Turcot, V, Zhan, X, Gong, J, Batini, C, Weissenkampen, J D, Liu, M, Barnes, D R, Bertelsen, S, Chou, Y-L, Erzurumluoglu, A M, Faul, J D, Haessler, J, Hammerschlag, A R, Hsu, C, Kapoor, M, Lai, D, Le, N, de Leeuw, C A, Loukola, A, Mangino, M, Melbourne, C A, Pistis, G, Qaiser, B, Rohde, R, Shao, Y, Stringham, H, Wetherill, L, Zhao, W, Agrawal, A, Bierut, L, Chen, C, Eaton, C B, Goate, A, Haiman, C, Heath, A, Iacono, W G, Martin, N G, Polderman, T J, Reiner, A, Rice, J, Schlessinger, D, Scholte, H S, Smith, J A, Tardif, J-C, Tindle, H A, van der Leij, A R, Boehnke, M, Chang-Claude, J, Cucca, F, David, S P, Foroud, T, Howson, J M M, Kardia, S L R, Kooperberg, C, Laakso, M, Lettre, G, Madden, P, Mcgue, M, North, K, Posthuma, D, Spector, T, Stram, D, Tobin, M D, Weir, D R, Kaprio, J, Abecasis, G R, Liu, D J, Vrieze, S, Surendran, P, Young, R, Barnes, D R, Nielsen, S F, Rasheed, A, Samuel, M, Zhao, W, Kontto, J, Perola, M, Caslake, M, de Craen, A J M, Trompet, S, Uria-Nickelsen, M, Malarstig, A, Reily, D F, Hoek, M, Vogt, T, Jukema, J W, Sattar, N, Ford, I, Packard, C J, Alam, D S, Majumder, A A S, Di Ange-Lantonio, E, Chowdhury, R, Amouyel, P, Arveiler, D, Blankenberg, S, Ferrieres, J, Kee, F, Kuulasmaa, K, Mueller-Nurasyid, M, Veronesi, G, Virtamo, J, Frossard, P, Nordestgaard, B G, Saleheen, D, Danesh, J, Butterworth, A S, Howson, J M M, Erzurumluoglu, A M, Jackson, V E, Melbourne, C A, Varga, T V, Warren, H R, Tragante, V, Tachmazidou, I, Harris, S E, Evangelou, E, Marten, J, Zhang, W, Altmaier, E, Luan, J, Langenberg, C, Scott, R A, Yaghootkar, H, Stirrups, K, Kanoni, S, Marouli, E, Karpe, F, Dominiczak, A F, Sever, P, Poulter, N, Rolandsson, O, Baumbach, C, Afaq, S, Chambers, J C, Kooner, J S, Wareham, N J, Renstrom, F, Hallmans, G, Marioni, R E, Corley, J, Starr, J M, Verweij, N, de Boer, R A, van der Meer, P, Yavas, E, Vaartjes, I, Bots, M L, Asselbergs, F W, Grabe, H J, Volzke, H, Nauck, M, Weiss, S, Pharoah, P D P, Dunning, A M, Dennis, J G, Thompson, D J, Michailidou, K, Easton, D F, Antoniou, A C, Tyrrell, J, Mihailov, E, Samani, N J, Zhou, K, Neville, M J, Metspalu, A, Palmer, C N A, Hall, I P, Strachan, D P, Deary, I J, Frayling, T M, Hayward, C, van der Harst, P, Zeggini, E, Munroe, P B, Jansson, J-H, Franks, P W, Deloukas, P, Caulfield, M J, Wain, L V & Tobin, M D 2019, ' Exome Chip Meta-analysis Fine Maps Causal Variants and Elucidates the Genetic Architecture of Rare Coding Variants in Smoking and Alcohol Use ', Biological Psychiatry, vol. 85, no. 11, pp. 946-955 . https://doi.org/10.1016/j.biopsych.2018.11.024
Biological Psychiatry, 85(11), 946. Elsevier USA
Brazel, D M, Jiang, Y, Hughey, J M, Turcot, V, Zhan, X, Gong, J, Batini, C, Weissenkampen, J D, Liu, M, Surendran, P, Young, R, Barnes, D R, Nielsen, S F, Rasheed, A, Samuel, M, Zhao, W, Kontto, J, Perola, M, Caslake, M, de Craen, A J M, Trompet, S, Uria-Nickelsen, M, Malarstig, A, Reily, D F, Hoek, M, Vogt, T, Jukema, J W, Sattar, N, Ford, I, Packard, C J, Alam, D S, Majumder, A A S, di Angelantonio, E, Chowdhury, R, Amouyel, P, Arveiler, D, Blankenberg, S, Ferrières, J, Kee, F, Kuulasmaa, K, Müller-Nurasyid, M, Veronesi, G, Virtamo, J, EPIC-CVD Consortium, Frossard, P, Nordestgaard, B R G, Saleheen, D, Danesh, J, Hammerschlag, A R, Posthuma, D, Spector, T, Stram, D O, Tobin, M D, Weir, D R, Kaprio, J, Abecasis, G R, Liu, D J, Vrieze, S & CHD Exome+ Consortium 2019, ' Exome Chip Meta-analysis Fine Maps Causal Variants and Elucidates the Genetic Architecture of Rare Coding Variants in Smoking and Alcohol Use ', Biological Psychiatry, vol. 85, no. 11, pp. 946-955 . https://doi.org/10.1016/j.biopsych.2018.11.024
Biological psychiatry. Elsevier USA
CHD Exome+ Consortium & Consortium for Genetics of Smoking Behaviour 2019, ' Exome Chip Meta-analysis Fine Maps Causal Variants and Elucidates the Genetic Architecture of Rare Coding Variants in Smoking and Alcohol Use ', Biological Psychiatry, vol. 85, no. 11, pp. 946-955 . https://doi.org/10.1016/j.biopsych.2018.11.024
Biological Psychiatry, 85(11), 946-955. Elsevier USA
Biological Psychiatry, 85(11), 946-955. ELSEVIER SCIENCE INC
Brazel, D M, Jiang, Y, Hughey, J M, Turcot, V, Zhan, X, Gong, J, Batini, C, Weissenkampen, J D, Liu, M, Barnes, D R, Bertelsen, S, Chou, Y-L, Erzurumluoglu, A M, Faul, J D, Haessler, J, Hammerschlag, A R, Hsu, C, Kapoor, M, Lai, D, Le, N, de Leeuw, C A, Loukola, A, Mangino, M, Melbourne, C A, Pistis, G, Qaiser, B, Rohde, R, Shao, Y, Stringham, H, Wetherill, L, Zhao, W, Agrawal, A, Bierut, L, Chen, C, Eaton, C B, Goate, A, Haiman, C, Heath, A, Iacono, W G, Martin, N G, Polderman, T J, Reiner, A, Rice, J, Schlessinger, D, Scholte, H S, Smith, J A, Tardif, J-C, Tindle, H A, van der Leij, A R, Boehnke, M, Chang-Claude, J, Cucca, F, David, S P, Foroud, T, Howson, J M M, Kardia, S L R, Kooperberg, C, Laakso, M, Lettre, G, Madden, P, Mcgue, M, North, K, Posthuma, D, Spector, T, Stram, D, Tobin, M D, Weir, D R, Kaprio, J, Abecasis, G R, Liu, D J, Vrieze, S, Surendran, P, Young, R, Barnes, D R, Nielsen, S F, Rasheed, A, Samuel, M, Zhao, W, Kontto, J, Perola, M, Caslake, M, de Craen, A J M, Trompet, S, Uria-Nickelsen, M, Malarstig, A, Reily, D F, Hoek, M, Vogt, T, Jukema, J W, Sattar, N, Ford, I, Packard, C J, Alam, D S, Majumder, A A S, Di Ange-Lantonio, E, Chowdhury, R, Amouyel, P, Arveiler, D, Blankenberg, S, Ferrieres, J, Kee, F, Kuulasmaa, K, Mueller-Nurasyid, M, Veronesi, G, Virtamo, J, Frossard, P, Nordestgaard, B G, Saleheen, D, Danesh, J, Butterworth, A S, Howson, J M M, Erzurumluoglu, A M, Jackson, V E, Melbourne, C A, Varga, T V, Warren, H R, Tragante, V, Tachmazidou, I, Harris, S E, Evangelou, E, Marten, J, Zhang, W, Altmaier, E, Luan, J, Langenberg, C, Scott, R A, Yaghootkar, H, Stirrups, K, Kanoni, S, Marouli, E, Karpe, F, Dominiczak, A F, Sever, P, Poulter, N, Rolandsson, O, Baumbach, C, Afaq, S, Chambers, J C, Kooner, J S, Wareham, N J, Renstrom, F, Hallmans, G, Marioni, R E, Corley, J, Starr, J M, Verweij, N, de Boer, R A, van der Meer, P, Yavas, E, Vaartjes, I, Bots, M L, Asselbergs, F W, Grabe, H J, Volzke, H, Nauck, M, Weiss, S, Pharoah, P D P, Dunning, A M, Dennis, J G, Thompson, D J, Michailidou, K, Easton, D F, Antoniou, A C, Tyrrell, J, Mihailov, E, Samani, N J, Zhou, K, Neville, M J, Metspalu, A, Palmer, C N A, Hall, I P, Strachan, D P, Deary, I J, Frayling, T M, Hayward, C, van der Harst, P, Zeggini, E, Munroe, P B, Jansson, J-H, Franks, P W, Deloukas, P, Caulfield, M J, Wain, L V & Tobin, M D 2019, ' Exome Chip Meta-analysis Fine Maps Causal Variants and Elucidates the Genetic Architecture of Rare Coding Variants in Smoking and Alcohol Use ', Biological Psychiatry, vol. 85, no. 11, pp. 946-955 . https://doi.org/10.1016/j.biopsych.2018.11.024
Biological Psychiatry, 85(11), 946. Elsevier USA
Brazel, D M, Jiang, Y, Hughey, J M, Turcot, V, Zhan, X, Gong, J, Batini, C, Weissenkampen, J D, Liu, M, Surendran, P, Young, R, Barnes, D R, Nielsen, S F, Rasheed, A, Samuel, M, Zhao, W, Kontto, J, Perola, M, Caslake, M, de Craen, A J M, Trompet, S, Uria-Nickelsen, M, Malarstig, A, Reily, D F, Hoek, M, Vogt, T, Jukema, J W, Sattar, N, Ford, I, Packard, C J, Alam, D S, Majumder, A A S, di Angelantonio, E, Chowdhury, R, Amouyel, P, Arveiler, D, Blankenberg, S, Ferrières, J, Kee, F, Kuulasmaa, K, Müller-Nurasyid, M, Veronesi, G, Virtamo, J, EPIC-CVD Consortium, Frossard, P, Nordestgaard, B R G, Saleheen, D, Danesh, J, Hammerschlag, A R, Posthuma, D, Spector, T, Stram, D O, Tobin, M D, Weir, D R, Kaprio, J, Abecasis, G R, Liu, D J, Vrieze, S & CHD Exome+ Consortium 2019, ' Exome Chip Meta-analysis Fine Maps Causal Variants and Elucidates the Genetic Architecture of Rare Coding Variants in Smoking and Alcohol Use ', Biological Psychiatry, vol. 85, no. 11, pp. 946-955 . https://doi.org/10.1016/j.biopsych.2018.11.024
Biological psychiatry. Elsevier USA
CHD Exome+ Consortium & Consortium for Genetics of Smoking Behaviour 2019, ' Exome Chip Meta-analysis Fine Maps Causal Variants and Elucidates the Genetic Architecture of Rare Coding Variants in Smoking and Alcohol Use ', Biological Psychiatry, vol. 85, no. 11, pp. 946-955 . https://doi.org/10.1016/j.biopsych.2018.11.024
BackgroundSmoking and alcohol use have been associated with common genetic variants in multiple loci. Rare variants within these loci hold promise in the identification of biological mechanisms in substance use. Exome arrays and genotype imputation c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c4c6686918e3fb0cec91a0a7423b4f4
https://dare.uva.nl/personal/pure/en/publications/exome-chip-metaanalysis-fine-maps-causal-variants-and-elucidates-the-genetic-architecture-of-rare-coding-variants-in-smoking-and-alcohol-use(5b2dcbfd-0c32-47f3-869f-1ff60f676314).html
https://dare.uva.nl/personal/pure/en/publications/exome-chip-metaanalysis-fine-maps-causal-variants-and-elucidates-the-genetic-architecture-of-rare-coding-variants-in-smoking-and-alcohol-use(5b2dcbfd-0c32-47f3-869f-1ff60f676314).html
Autor:
Peter D. Sly, Re Foong, Ozren Polasek, Nicole Probst-Hensch, Ian P. Hall, Graham L. Hall, Tobin, Pirro G. Hysi, Teemu Palviainen, Mika Kähönen, Veronique Vitart, Louise V. Wain, Carl A. Melbourne, Don D. Sin, Anna L. Guyatt, Henry Völzke, Ca Wang, Katherine A. Fawcett, David J. Porteous, John M. Starr, Claudia Langenberg, Igor Rudan, Ke Hao, Stefan Weiss, Terho Lehtimäki, Kirsi H. Pietiläinen, David M. Evans, Ian J. Deary, Jian'an Luan, James F. Wilson, David P. Strachan, Taina Rantanen, Catherine John, Nicola Pirastu, O T Raitakari, Berge M van den, Karina Patasova, Claudia Flexeder, Medea Imboden, Thibaud Boutin, Mangino Massimo, Archie Campbell, Lucija Klaric, Leo-Pekka Lyytikäinen, Nick Shrine, Sebastian May-Wilson, Beate Stubbe, Ralf Ewert, Dirk Keidel, Sarah E. Harris, Tim D. Spector, Ma'en Obeidat, John Henderson, Cosetta Minelli, Moksnes, Raquel Granell, Blair H. Smith, Arnulf Langhammer, Craig E. Pennell, Nicholas J. Wareham, Caroline Hayward, Ben Michael Brumpton, Yohan Bossé, Peter K. Joshi, Susan M. Ring, Sandosh Padmanabhan, Cristen J. Willer, Kristian Hveem, Deborah Jarvis, J Kaprio, Laura Portas, Anne Richmond
Adult lung function is highly heritable and 279 genetic loci were recently reported as associated with spirometry-based measures of lung function. Though lung development and function differ between males and females throughout life, there has been n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67d8b91786df855b049a3c8f757942a6
https://doi.org/10.1101/594457
https://doi.org/10.1101/594457
Autor:
Chris Finan, Yoav Ben-Shlomo, Eric B. Larson, Tine Jess, Richard W Morris, Daniel I. Chasman, Fernando Pires Hartwig, Catherine Welch, Rodney J. Scott, Helen E. Speedy, Andrzej Pajak, Raha Pazoki, André G. Uitterlinden, Torben Hansen, Marc Sanson, Hakon Hakonarson, Claudia Langenberg, Joey Ward, John Wright, Dorothée Thuillier, Ben Kinnersley, Diederick E. Grobbee, Yvonne T. van der Schouw, Pieter Sonneveld, Michiel L. Bots, Harold Snieder, Karim Labreche, Dan M. Roden, Archie Campbell, Melissa C. Smart, Christine Power, Pim van der Harst, Amélie Bonnefond, Ingrid E. Christophersen, Riyaz S. Patel, Uwe Völker, Stephen Hancock, Niels Grarup, Dennis O. Mook-Kanamori, Mariza de Andrade, Caroline Dale, N. Charlotte Onland-Moret, David R. Crosslin, Meena Kumari, Erik Ingelsson, Michael V. Holmes, Spiros Denaxas, Sudha Seshadri, Kees Hovingh, Marcus Dörr, Paul M. Ridker, Stefan Coassin, Albert Hofman, Andrew N. Nicolaides, Oluf Pedersen, Philippe Froguel, Simonetta Guarrera, Murray H. Brilliant, Sara E. Dobbins, Salim Yusuf, Kari Hemminki, Erik P A Van Iperen, Abbas Dehghan, Jill P. Pell, Alexander Teumer, Peter W. Schofield, Aroon D. Hingorani, Dan Mason, Amand F. Schmidt, Rui Bebiano Da Providencia E Costa, James M. Allan, Leslie A. Lange, Niels Weinhold, Stefan Gustafsson, Jackie F. Price, Mika Kivimäki, Hynek Pikhart, Kirchner H. Lester, Lars Lind, Philip J. Law, Cara L. Carty, David Preiss, Richard S. Houlston, Robin Young, Tom W. Meade, Martin O'Donnell, Alexander P. Reiner, Ni Li, Oscar H. Franco, Zammy Fairhurst-Hunter, Ronan Roussel, Tim Christen, Ilja Demuth, David Carrell, Catherine A. McCarty, Juan P. Casas, Johann Willeit, Peter H. Whincup, Stela McLachlan, Adelaida Sanchez-Galvez, Hartmut Goldschmidt, Guillaume Paré, Harry Hemingway, Anubha Mahajan, Elisabeth Steinhagen-Thiessen, Elizabeth G. Holliday, Giuseppe Matullo, Henry Völzke, Ian Ford, Martin Bobak, Pedro Marques-Vidal, Bertrand Cariou, Bernardo L. Horta, Melissa L. Bondy, Goya Wanamethee, Naveed Sattar, Steve E. Humphries, Marylyn D. Ritchie, Kristina Norman, Carlotta Sacerdote, Giovanni Fiorito, Sebastian E. Baumeister, Amit Sud, Dennis Valentine, Andreas Engert, Juri Demuth, Rupert Faraway, Abdonas Tamosiunas, Andrie G. Panayiotou, Terrie Kitchner, Lars Bertram, Sandosh Padmanabhan, Sofia Malyutina, Anke H. Maitland-van der Zee, Alex J. Cornish, Joshua C. Denny, Jian'an Luan, Robert A. Scott, Daniel I. Swerdlow, John Attia, Karin Willeit, Gareth J. Morgan, Michael Chong, Ruben N. Eppinga, Elina Hyppönen, Ekaterina V. Baranova, Jackie A. Cooper, Ghazaleh Fatemifar, Niek Verweij, Max Moldovan, Brendan J. Keating, M. Abdullah Said, Markus M. Lerch, Christina M. Lill, Markus Hansson, Jemma C. Hopewell, Björn Nilsson, Folkert W. Asselbergs, Ruzena Kubinova, Molly Went, Nicholas J. Wareham, Stefan Kiechl, Yanchun Bao, Allan Linneberg, Matthias Simon
Publikováno v:
BMC Cardiovascular Disorders, 19(1). BMC
Schmidt, Amand F; Holmes, Michael V; Preiss, David; Swerdlow, Daniel I; Denaxas, Spiros; Fatemifar, Ghazaleh; Faraway, Rupert; Finan, Chris; Valentine, Dennis; Fairhurst-Hunter, Zammy; Hartwig, Fernando Pires; Horta, Bernardo Lessa; Hypponen, Elina; Power, Christine; Moldovan, Max; van Iperen, Erik; Hovingh, Kees; Demuth, Ilja; Norman, Kristina; Steinhagen-Thiessen, Elisabeth; ... (2019). Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9. BMC cardiovascular disorders, 19(1), p. 240. BioMed Central 10.1186/s12872-019-1187-z
BMC cardiovascular disorders, 19(1):240. BioMed Central
BMC cardiovascular disorders, London : BioMed Central, 2019, vol. 19, no. 1, 240, p. 1-10
BMC Cardiovascular Disorders
BMC Cardiovascular Disorders, 19(1). BioMed Central
BMC Cardiovascular Disorders, Vol 19, Iss 1, Pp 1-10 (2019)
Schmidt, A F, Holmes, M V, Preiss, D, Swerdlow, D I, Denaxas, S, Fatemifar, G, Faraway, R, Finan, C, Valentine, D, Fairhurst-Hunter, Z, McLachlan, S & Price, J 2019, ' Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9 ', Bmc cardiovascular disorders . https://doi.org/10.1186/s12872-019-1187-z
BMC Cardiovascular Disorders, 19(1):240. BioMed Central Ltd.
Schmidt, A F, Holmes, M V, Preiss, D, Swerdlow, D I, Denaxas, S, Fatemifar, G, Faraway, R, Finan, C, Valentine, D, Fairhurst-Hunter, Z, Hartwig, F P, Horta, B L, Hypponen, E, Power, C, Moldovan, M, Van Iperen, E, Hovingh, K, Demuth, I, Norman, K, Steinhagen-Thiessen, E, Demuth, J, Bertram, L, Lill, C M, Coassin, S, Willeit, J, Kiechl, S, Willeit, K, Mason, D, Wright, J, Morris, R, Wanamethee, G, Whincup, P, Ben-Shlomo, Y, McLachlan, S, Price, J F, Kivimaki, M, Welch, C, Sanchez-Galvez, A, Marques-Vidal, P, Nicolaides, A, Panayiotou, A G, Onland-Moret, N C, Van Der Schouw, Y T, Matullo, G, Fiorito, G, Guarrera, S, Sacerdote, C, Wareham, N J, Langenberg, C, Scott, R A, Luan, JA, Bobak, M, Malyutina, S, Pajak, A, Kubinova, R, Tamosiunas, A, Pikhart, H, Grarup, N, Pedersen, O, Hansen, T, Linneberg, A, Jess, T, Cooper, J, Humphries, S E, Brilliant, M, Kitchner, T, Hakonarson, H, Carrell, D S, McCarty, C A, Lester, K H, Larson, E B, Crosslin, D R, De Andrade, M, Roden, D M, Denny, J C, Carty, C, Hancock, S, Attia, J, Holliday, E, Scott, R, Schofield, P, O'Donnell, M, Yusuf, S, Chong, M, Pare, G, Van Der Harst, P, Said, M A, Eppinga, R N, Verweij, N, Snieder, H, Christen, T, Mook-Kanamori, D O, Gustafsson, S, Lind, L, Ingelsson, E, Pazoki, R, Franco, O, Hofman, A, Uitterlinden, A, Dehghan, A, Teumer, A, Baumeister, S, Dörr, M, Lerch, M M, Völker, U, Völzke, H, Ward, J, Pell, J P, Meade, T, Christophersen, I E, Maitland-Van Der Zee, A H, Baranova, E V, Young, R, Ford, I, Campbell, A, Padmanabhan, S, Bots, M L, Grobbee, D E, Froguel, P, Thuillier, D, Roussel, R, Bonnefond, A, Cariou, B, Smart, M, Bao, Y, Kumari, M, Mahajan, A, Hopewell, J C, Seshadri, S, Dale, C, Costa, R P E, Ridker, P M, Chasman, D I, Reiner, A P, Ritchie, M D, Lange, L A, Cornish, A J, Dobbins, S E, Hemminki, K, Kinnersley, B, Sanson, M, Labreche, K, Simon, M, Bondy, M, Law, P, Speedy, H, Allan, J, Li, N, Went, M, Weinhold, N, Morgan, G, Sonneveld, P, Nilsson, B, Goldschmidt, H, Sud, A, Engert, A, Hansson, M, Hemingway, H, Asselbergs, F W, Patel, R S, Keating, B J, Sattar, N, Houlston, R, Casas, J P & Hingorani, A D 2019, ' Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9 ', BMC Cardiovascular Disorders, vol. 19, no. 1, 240 . https://doi.org/10.1186/s12872-019-1187-z
Schmidt, Amand F; Holmes, Michael V; Preiss, David; Swerdlow, Daniel I; Denaxas, Spiros; Fatemifar, Ghazaleh; Faraway, Rupert; Finan, Chris; Valentine, Dennis; Fairhurst-Hunter, Zammy; Hartwig, Fernando Pires; Horta, Bernardo Lessa; Hypponen, Elina; Power, Christine; Moldovan, Max; van Iperen, Erik; Hovingh, Kees; Demuth, Ilja; Norman, Kristina; Steinhagen-Thiessen, Elisabeth; ... (2019). Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9. BMC cardiovascular disorders, 19(1), p. 240. BioMed Central 10.1186/s12872-019-1187-z
BMC cardiovascular disorders, 19(1):240. BioMed Central
BMC cardiovascular disorders, London : BioMed Central, 2019, vol. 19, no. 1, 240, p. 1-10
BMC Cardiovascular Disorders
BMC Cardiovascular Disorders, 19(1). BioMed Central
BMC Cardiovascular Disorders, Vol 19, Iss 1, Pp 1-10 (2019)
Schmidt, A F, Holmes, M V, Preiss, D, Swerdlow, D I, Denaxas, S, Fatemifar, G, Faraway, R, Finan, C, Valentine, D, Fairhurst-Hunter, Z, McLachlan, S & Price, J 2019, ' Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9 ', Bmc cardiovascular disorders . https://doi.org/10.1186/s12872-019-1187-z
BMC Cardiovascular Disorders, 19(1):240. BioMed Central Ltd.
Schmidt, A F, Holmes, M V, Preiss, D, Swerdlow, D I, Denaxas, S, Fatemifar, G, Faraway, R, Finan, C, Valentine, D, Fairhurst-Hunter, Z, Hartwig, F P, Horta, B L, Hypponen, E, Power, C, Moldovan, M, Van Iperen, E, Hovingh, K, Demuth, I, Norman, K, Steinhagen-Thiessen, E, Demuth, J, Bertram, L, Lill, C M, Coassin, S, Willeit, J, Kiechl, S, Willeit, K, Mason, D, Wright, J, Morris, R, Wanamethee, G, Whincup, P, Ben-Shlomo, Y, McLachlan, S, Price, J F, Kivimaki, M, Welch, C, Sanchez-Galvez, A, Marques-Vidal, P, Nicolaides, A, Panayiotou, A G, Onland-Moret, N C, Van Der Schouw, Y T, Matullo, G, Fiorito, G, Guarrera, S, Sacerdote, C, Wareham, N J, Langenberg, C, Scott, R A, Luan, JA, Bobak, M, Malyutina, S, Pajak, A, Kubinova, R, Tamosiunas, A, Pikhart, H, Grarup, N, Pedersen, O, Hansen, T, Linneberg, A, Jess, T, Cooper, J, Humphries, S E, Brilliant, M, Kitchner, T, Hakonarson, H, Carrell, D S, McCarty, C A, Lester, K H, Larson, E B, Crosslin, D R, De Andrade, M, Roden, D M, Denny, J C, Carty, C, Hancock, S, Attia, J, Holliday, E, Scott, R, Schofield, P, O'Donnell, M, Yusuf, S, Chong, M, Pare, G, Van Der Harst, P, Said, M A, Eppinga, R N, Verweij, N, Snieder, H, Christen, T, Mook-Kanamori, D O, Gustafsson, S, Lind, L, Ingelsson, E, Pazoki, R, Franco, O, Hofman, A, Uitterlinden, A, Dehghan, A, Teumer, A, Baumeister, S, Dörr, M, Lerch, M M, Völker, U, Völzke, H, Ward, J, Pell, J P, Meade, T, Christophersen, I E, Maitland-Van Der Zee, A H, Baranova, E V, Young, R, Ford, I, Campbell, A, Padmanabhan, S, Bots, M L, Grobbee, D E, Froguel, P, Thuillier, D, Roussel, R, Bonnefond, A, Cariou, B, Smart, M, Bao, Y, Kumari, M, Mahajan, A, Hopewell, J C, Seshadri, S, Dale, C, Costa, R P E, Ridker, P M, Chasman, D I, Reiner, A P, Ritchie, M D, Lange, L A, Cornish, A J, Dobbins, S E, Hemminki, K, Kinnersley, B, Sanson, M, Labreche, K, Simon, M, Bondy, M, Law, P, Speedy, H, Allan, J, Li, N, Went, M, Weinhold, N, Morgan, G, Sonneveld, P, Nilsson, B, Goldschmidt, H, Sud, A, Engert, A, Hansson, M, Hemingway, H, Asselbergs, F W, Patel, R S, Keating, B J, Sattar, N, Houlston, R, Casas, J P & Hingorani, A D 2019, ' Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9 ', BMC Cardiovascular Disorders, vol. 19, no. 1, 240 . https://doi.org/10.1186/s12872-019-1187-z
BackgroundWe characterised the phenotypic consequence of genetic variation at the PCSK9 locus and compared findings with recent trials of pharmacological inhibitors of PCSK9.MethodsPublished and individual participant level data (300,000+ participant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e8a7b3e5163aceb6019624e27507e6b
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-401186
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-401186
Autor:
Dennis O. Mook-Kanamori, J M Gaziano, Harst Pvd., Derek Klarin, K A Birdwell, Josh C. Denny, Martin Farrall, Thibaud Boutin, Najim Lahrouchi, Nabi Shah, Scott M. Damrauer, Cecilia P. Chung, Neil Poulter, Herzig K-H., E E Siew, John Concato, Yan V. Sun, Sara M. Willems, Louise V. Wain, Philip S. Tsao, Massimo Mangino, Wei W-Q., Ioanna Ntalla, Brian S. Mautz, David Schlessinger, Daniel I. Chasman, Branwen J. Hennig, Christopher Newton-Cheh, Michael E. Matheny, Palmer Cna., Caroline Hayward, Zhao J-H., Eleftheria Zeggini, Paul Elliott, C M Lindgren, Praveen Surendran, Csaba P. Kovesdy, Jacob M. Keaton, Chengxiang Qiu, Claudia Langenberg, Christopher Oldmeadow, Stéphanie Debette, D.R. Velez Edwards, Evangelos Evangelou, Howson Jmm., Adriana M. Hung, Yaomin Xu, Nicholas J. Wareham, James P. Cook, Scott L. DuVall, Peter Almgren, Jacklyn N. Hellwege, Sébastien Thériault, Helen R. Warren, Jian'an Luan, Ching-Ti Liu, Christopher J. O'Donnell, Michael Boehnke, Peter S. Sever, Ruifang Li-Gao, Cassianne Robinson-Cohen, Robert A. Scott, Muralidharan Sargurupremraj, Mark J. Caulfield, Jarvelin M-R., Tim D. Spector, Todd L. Edwards, Elena V. Feofanova, Francesco Cucca, Jihwan Park, Savita Karthikeyan, J C Smith, Wilson Pwf., Markku Laakso, Ayush Giri, Christianne L. Roumie, Rojesh Shrestha, Claudia P. Cabrera, Kelly Cho, Laura J. Scott, Elvis A. Akwo, Yu Wang, Tom G. Richardson, Patricia B. Munroe, Eric S. Torstenson, Katalin Susztak, John Attia, Bruce M. Psaty, Aldi T. Kraja, Olle Melander, Nicholas J. Timpson, George Dedoussis, Paul M. Ridker, Niek Verweij, David Conen, Philippe Amouyel, Otis D. Wilson, Nuno Sepúlveda
Publikováno v:
NATURE GENETICS
Nature Genetics
Nature Genetics, Nature Publishing Group, 2019, 51 (1), pp.51-62. ⟨10.1038/s41588-018-0303-9⟩
Nature Genetics, 51(1), 51
Nature genetics, 51(1), 51-62. Nature Publishing Group
Nature Genetics, 51(1), 51-62. Nature Publishing Group
Giri, A, Hellwege, J N, Keaton, J M, Park, J, Qiu, C, Warren, H R, Torstenson, E S, Kovesdy, C P, Sun, Y V, Wilson, O D, Robinson-Cohen, C, Roumie, C L, Chung, C P, Birdwell, K A, Damrauer, S M, DuVall, S L, Klarin, D, Cho, K, Wang, Y, Evangelou, E, Cabrera, C P, Wain, L V, Shrestha, R, Mautz, B S, Akwo, E A, Sargurupremraj, M, Debette, S, Boehnke, M, Scott, L J, Luan, J, Zhao, J-H, Willems, S M, Thériault, S, Shah, N, Oldmeadow, C, Almgren, P, Li-Gao, R, Verweij, N, Boutin, T S, Mangino, M, Ntalla, I, Feofanova, E, Surendran, P, Cook, J P, Richardson, T G, Zeggini, E, Scott, R A, Palmer, C N A & Timpson, N J & Wilson, P W F 2019, ' Trans-ethnic association study of blood pressure determinants in over 750,000 individuals ', Nature Genetics, vol. 51, no. 1, pp. 51-62 . https://doi.org/10.1038/s41588-018-0303-9
Nature Genetics
Nature Genetics, Nature Publishing Group, 2019, 51 (1), pp.51-62. ⟨10.1038/s41588-018-0303-9⟩
Nature Genetics, 51(1), 51
Nature genetics, 51(1), 51-62. Nature Publishing Group
Nature Genetics, 51(1), 51-62. Nature Publishing Group
Giri, A, Hellwege, J N, Keaton, J M, Park, J, Qiu, C, Warren, H R, Torstenson, E S, Kovesdy, C P, Sun, Y V, Wilson, O D, Robinson-Cohen, C, Roumie, C L, Chung, C P, Birdwell, K A, Damrauer, S M, DuVall, S L, Klarin, D, Cho, K, Wang, Y, Evangelou, E, Cabrera, C P, Wain, L V, Shrestha, R, Mautz, B S, Akwo, E A, Sargurupremraj, M, Debette, S, Boehnke, M, Scott, L J, Luan, J, Zhao, J-H, Willems, S M, Thériault, S, Shah, N, Oldmeadow, C, Almgren, P, Li-Gao, R, Verweij, N, Boutin, T S, Mangino, M, Ntalla, I, Feofanova, E, Surendran, P, Cook, J P, Richardson, T G, Zeggini, E, Scott, R A, Palmer, C N A & Timpson, N J & Wilson, P W F 2019, ' Trans-ethnic association study of blood pressure determinants in over 750,000 individuals ', Nature Genetics, vol. 51, no. 1, pp. 51-62 . https://doi.org/10.1038/s41588-018-0303-9
International audience; In this trans-ethnic multi-omic study, we reinterpret the genetic architecture of blood pressure to identify genes, tissues, phenomes and medication contexts of blood pressure homeostasis. We discovered 208 novel common blood
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fc65101b526e49b26bca973f7ee89ec