Zobrazeno 71 - 80
of 124
pro vyhledávání: '"544"'
Autor:
Tanja Kunej, Blaz Skrlj
Publikováno v:
Computers in biology and medicine. 79
BackgroundProtein-protein interactions (PPI) play an important role in function of all organisms and enable understanding of underlying metabolic processes. Computational predictions of PPIs are an important aspect in proteomics, as experimental meth
Publikováno v:
Iranian Red Crescent Medical Journal
Background: Mutations in the solute carrier family 22 member 3 (SLC22A3), lipoprotein (a)-like 2 (LPAL2), and the lipoprotein (a) (LPA) gene cluster, which encodes apolipoprotein (a) [apo (a)] of the lipoprotein (a) [Lp (a)] lipoprotein particle, hav
Autor:
Eman A. Dashti, Sose H. Keleshian, Ahmad W. Almawi, Noha Irani-Hakime, Wassim Y. Almawi, Akram Echtay, A.S. Al-Busaidi, Rita Nemr
Publikováno v:
Diabetes Research and Clinical Practice. 96:225-229
Several genome-wide association studies and replication analyses have identified common variation at the insulin-like binding protein 2 (IGF2BP2) gene to be associated with type 2 diabetes (T2DM). The aim of this study was to replicate in a Lebanese
Autor:
Ai-ling Zhang, Liangzhi Zhang, Hong Chen, Xianyong Lan, Chunlei Zhang, Li Zhang, Cunfang Zhang
Publikováno v:
Molecular Biology Reports. 39:6981-6986
Ghrelin is an important peptide that stimulates food intake and regulates energy balance of animals. Single nucleotide polymorphisms of ghrelin gene in three Chinese cattle populations were investigated through PCR-SSCP and DNA sequencing. Five over-
Autor:
Xingqiu Zhao, Mark S. Silverberg, Anne M. Griffiths, Aleixo M. Muise, Victorien M. Wolters, Wei Xu, Thomas D. Walters
Publikováno v:
Human Immunology. 72:592-597
Various genes that may influence the intestinal barrier have been identified, including MAGI2, PARD3, and MYO9B. These genes are associated with inflammatory bowel disease (IBD) in several European studies. A total of 2,049 individuals (656 Crohn's d
Autor:
Stalo Karageorgi, Monica McGrath, Julie E. Buring, Peter Kraft, Immaculata De Vivo, I-Min Lee
Publikováno v:
Gynecologic Oncology. 121:54-58
Hydroxysteroid-dehydrogenase-17b (HSD17b) genes control the last step in estrogen biosynthesis. The isoenzymes HSD17b2 and HSD17b4 in the uterus preferentially catalyze the conversion of estradiol, the most potent and active form of estrogen, to estr
Autor:
Yuichi Shiraishi, Tetsuichi Yoshizato, Kenichi Chiba, Nobuyuki Kakiuchi, Satoru Miyano, Kenichi Yoshida, Yoshikage Inoue, Yoshiharu Sakai, Satoshi Nagayama, Yusuke Shiozawa, Seishi Ogawa
Publikováno v:
Cancer Research. 78:1426-1426
Introduction Extensive genetic studies of recent years using next generation sequencing have clarified a comprehensive registry of genetic alteration in colorectal cancer (CRC). However, the clinical impacts of these genetic alterations have not full
Autor:
Grier P. Page, Benjamin J. Cargile, Xinxin Zhang, Huaqin Pan, Phillip C Cooley, Maureen K. Bunger, Megan D. Rowland, Nikhil Garge
Publikováno v:
Molecular & Cellular Proteomics. 9:1383-1399
Population-based variability in protein expression patterns, especially in humans, is often observed but poorly understood. Moreover, very little is known about how interindividual genetic variation contributes to protein expression patterns. To begi
Autor:
Vladimir P. Pushkarev, Nir Eynon, Paweł Cięszczyk, Agata Leońska-Duniec, Lauren K Banting, Evgeniy F Orekhov, Aleksandra Zarębska, Ruth Birk, Xu Yan, Yuliya E. Pushkareva, Aleksandr V Degtyarev, Marek Sawczuk, Dmitry A. Dyatlov, Agnieszka Maciejewska-Karlowska
Publikováno v:
BMC Genomics
Background Genetic variants may predispose humans to elevated risk of common metabolic morbidities such as obesity and Type 2 Diabetes (T2D). Some of these variants have also been shown to influence elite athletic performance and the response to exer
Autor:
Aurélie Labbe, Erika N. Dugas, Igor Karp, Marie-Hélène Roy-Gagnon, Marie-Pierre Sylvestre, James C. Engert, Jennifer O'Loughlin, Nancy Low
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e115716 (2014)
PLoS ONE
PLoS ONE
Background: While the heritability of cigarette smoking and nicotine dependence (ND) is well-documented, the contribution of specific genetic variants to specific phenotypes has not been closely examined. The objectives of this study were to test the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0da1cbd548080ab97208137c345012c
https://doi.org/10.1371/journal.pone.0115716
https://doi.org/10.1371/journal.pone.0115716