Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Mario Mancino"'
Autor:
Coline H M van Moorsel, Ana Montes-Worboys, Razq Hakem, E. Ellen Billett, Carmen Herranz, Eline Blommaert, Oscar Yanes, Antonio Roman, Julio Ancochea, Álvaro Casanova, Raúl Rigo-Bonnin, Harilaos Filippakis, Berta Saez, August Vidal, Alexandra Baiges, Antoni Xaubet, Suzanne Miller, Antonio Gomez, Roderic Espín, Joanne J van der Vis, José A Rodríguez-Portal, Chiara Gorrini, Jaume Bordas, Marian J R Quanjel, Aleix Noguera-Castells, Luis Palomero, Eva Revilla-López, Josep M. Cruzado, Xiaohu Zhang, Enrique Lastra, Nadia García, Elżbieta Radzikowska, Marc Ferrer, Simon R. Johnson, Christophe Bontoux, Maria Molina-Molina, Alexandra Junza, Javier A. Menendez, Ana I. Extremera, Piedad Ussetti, Rosalía Laporta, Álvaro Lahiguera, Miquel Angel Pujana, Susana Gómez-Ollés, Daniel Cuadras, Mario Mancino, Claudia Valenzuela, Tamara Alonso, Jose C. Perales, Francesca Mateo, Francesc Viñals, Aslihan Ugun-Klusek, Gorka Ruiz de Garibay, Roser Guiteras, Jordi Capellades, Concettina La Motta, Carlos Machahua
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
EMBO Molecular Medicine
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Scientia
DDFV. Repositorio Institucional de la Universidad Francisco de Vitoria
Dipòsit Digital de la UB
Universidad de Barcelona
EMBO Molecular Medicine, Vol 13, Iss 9, Pp n/a-n/a (2021)
instname
EMBO Molecular Medicine
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Scientia
DDFV. Repositorio Institucional de la Universidad Francisco de Vitoria
Dipòsit Digital de la UB
Universidad de Barcelona
EMBO Molecular Medicine, Vol 13, Iss 9, Pp n/a-n/a (2021)
Inhibition of mTOR is the standard of care for lymphangioleiomyomatosis (LAM). However, this therapy has variable tolerability and some patients show progressive decline of lung function despite treatment. LAM diagnosis and monitoring can also be cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3528695e98889a787bd38a10b1b3e32
http://hdl.handle.net/10261/265901
http://hdl.handle.net/10261/265901
Autor:
Patricia Jauregui, Aleix Noguera-Castells, Raul Alonso, Silvia Menendez, Laia Serrano, Elisabet Ametller, Ana Lluch, L. Alex Gaither, Federico Rojo, Paloma Bragado, Pere Gascón, Leire Recalde-Percaz, Mario Mancino, Ana Rovira, Estel Enreig, Núria Moragas, Joan Albanell, Patricia Fernández-Nogueira, Vanessa Almendro, Anke Bill, Gemma Fuster, Anna López-Plana
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
instname
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
instname
Purpose:Despite the therapeutic success of existing HER2-targeted therapies, tumors invariably relapse. This study aimed at identifying new mechanisms responsible for HER2-targeted therapy resistance.Experimental Design:We have used a platform of HER
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e227e565ba327bbbd44f395147ae2e89
https://www.fundanet.incliva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=4333
https://www.fundanet.incliva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=4333
Autor:
Kazuhide Watanabe, Enza Lonardo, Caterina Bianco, Luigi Strizzi, Andrew E. Arai, David S. Salomon, Tadahiro Nagaoka, Mario Mancino, Gabriella Minchiotti, Monica Gonzales, Christina Baraty, Colin Berry, Catherine Cotten
Publikováno v:
The American journal of pathology
175 (2009): 2146–2158. doi:10.2353/ajpath.2009.090218
info:cnr-pdr/source/autori:Bianco C.; Cotten C.; Lonardo E.; Strizzi L.; Baraty C.; Mancino M.; Gonzales M.; Watanabe K.; Nagaoka T.; Berry C.; Arai A.E.; Minchiotti G.; Salomon D.S./titolo:Cripto-1 is required for hypoxia to induce cardiac differentiation of mouse embryonic stem cells/doi:10.2353%2Fajpath.2009.090218/rivista:The American journal of pathology (Print)/anno:2009/pagina_da:2146/pagina_a:2158/intervallo_pagine:2146–2158/volume:175
175 (2009): 2146–2158. doi:10.2353/ajpath.2009.090218
info:cnr-pdr/source/autori:Bianco C.; Cotten C.; Lonardo E.; Strizzi L.; Baraty C.; Mancino M.; Gonzales M.; Watanabe K.; Nagaoka T.; Berry C.; Arai A.E.; Minchiotti G.; Salomon D.S./titolo:Cripto-1 is required for hypoxia to induce cardiac differentiation of mouse embryonic stem cells/doi:10.2353%2Fajpath.2009.090218/rivista:The American journal of pathology (Print)/anno:2009/pagina_da:2146/pagina_a:2158/intervallo_pagine:2146–2158/volume:175
Cripto-1 is a membrane-bound protein that is highly expressed in embryonic stem cells and in human tumors. in the present study, we investigated the effect of low levels of oxygen, which occurs naturally in rapidly growing tissues, on Cripto-1 expres
Autor:
Caterina Bianco, Kazuhide Watanabe, Monica Gonzales, Margaret Mysliwiec, Tadahiro Nagaoka, Mario Mancino, David S. Salomon
Publikováno v:
FEBS Letters. 582:3997-4002
Cripto-1, a co-receptor for Nodal, can activate Nodal-dependent and Nodal-independent signaling pathways. In this study we have investigated whether Cripto-1 mutants, that fail to activate a Nodal-dependent signaling pathway, are capable to activate
Autor:
Mario Mancino, Shin Hamada, Tadahiro Nagaoka, Luigi Strizzi, David S. Salomon, Monica Gonzales, Caterina Bianco, Veronique Bailly, Kazuhide Watanabe
Publikováno v:
Journal of Biological Chemistry. 282:35772-35786
Cripto-1 (CR-1) has an indispensable role as a Nodal co-receptor for patterning of body axis in embryonic development. CR-1 is reported to have a paracrine activity as a Nodal co-receptor, although CR-1 is primarily produced as a glycosylphosphatidyl
Autor:
Luigi Strizzi, Mario Mancino, Nicola Normanno, Caterina Bianco, A. D'Antonio, S Lawson, Morihisa Hirota, David S. Salomon, Ahmed Raafat, Simona Losito, Shin Hamada, Andreas D. Ebert, Kazuhide Watanabe
Publikováno v:
The Journal of Pathology. 211:36-44
Overexpression of Cripto-1 (CR-1) in FVB/N mice using the MMTV-LTR promoter results in increased mammary tumourigenesis in these female transgenic mice (MMTV-CR-1). Here, we characterize uterine tumours that developed in 15/76 (19.7%) of MMTV-CR-1 fe
Autor:
Gemma Fuster, Mario Mancino, Xavier Gonzalez-Farre, Pedro Gascón, So Yeon Park, Elisabet Ametller, Eva María Pastor-Arroyo, Domiziana Costamagna, Hege G. Russnes, Pedro L. Fernández, Patricia Fernández-Nogueira, Pablo Engel, Vanessa Almendro, Susana García-Recio, Cristina Mayordomo
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname
ERBB receptor transmodulation by heterologous G-protein–coupled receptors (GPCR) generates functional diversity in signal transduction. Tachykinins are neuropeptides and proinflammatory cytokines that promote cell survival and cancer progression by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a6551c5f54d6bacfd1163553414fc7a
http://hdl.handle.net/2445/120272
http://hdl.handle.net/2445/120272
Publikováno v:
Breast Cancer in the Post-Genomic Era ISBN: 9781603279444
Members of the Epidermal Growth Factor-Cripto-1/FRL-1/Cryptic (EGF-CFC) family, such as human Cripto-1, are important mediators of crucial events that take place during embryonic pattern formation. New evidences from gene expression and transgenic mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c0713bc9c5bb5da2922922d1008c1d99
https://doi.org/10.1007/978-1-60327-945-1_6
https://doi.org/10.1007/978-1-60327-945-1_6
Autor:
Shin Hamada, Kazuhide Watanabe, Morihisa Hirota, Luigi Strizzi, Mario Mancino, David S. Salomon, Youping Sun, Masaharu Seno, Tadahiro Nagaoka, Caterina Bianco, Monica Gonzales
Both canonical Wnt/beta-catenin and TGFbeta/Smad signaling pathways coordinately regulate pattern formation during embryogenesis as well as tumor progression. Evidence of cross-talk between these two pathways has been reported. Here we demonstrated t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b37bd170925057bf1e40794e6032c44a
https://europepmc.org/articles/PMC2578836/
https://europepmc.org/articles/PMC2578836/
Autor:
Sylvie Ménard, Manuela Campiglio, Marianna Gallo, Amelia D'Alessio, Antonella De Luca, Monica R. Maiello, Nicola Normanno, Mario Mancino
Publikováno v:
Breast cancer research and treatment. 112(1)
Although the epidermal growth factor receptor (EGFR) is frequently expressed in human primary breast carcinoma, the majority of breast cancer patients do not respond to treatment with EGFR tyrosine-kinase inhibitors such as gefitinib. We isolated thr