Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Lucia Knopfová"'
Publikováno v:
Cellular signalling
The c-Myb transcription factor is important for maintenance of immature cells of many tissues including colon epithelium. Overexpression of c-Myb occurring in colorectal carcinomas (CRC) as well as in other cancers often marks poor prognosis. However
Autor:
Michal Masarik, Veronika Dvorakova, Martina Raudenská, Hana Polanska, René Kizek, Vojtech Adam, Jaromír Gumulec, Kristyna Hudcova, Lucia Knopfová, Jan Balvan, Petr Babula, Branislav Ruttkay-Nedecky, Marie Stiborová, Markéta Sztalmachová
Publikováno v:
International Journal of Oncology. 44:923-933
Differences in the antioxidant system, apoptotic mechanism and in cell cycle between prostatic cell lines could partially elucidate the development of cisplatin resistance. The aim of this study was to identify the most characteristic parameter for a
Autor:
Jan Šmarda, Lucia Knopfová
Publikováno v:
Experimental and Therapeutic Medicine. 1:257-264
Increased production of the pro-inflammatory enzyme cyclooxygenase-2 (Cox-2) and altered expression and activity of peroxisome proliferator-activated receptor γ (PPARγ) have been observed in many malignancies. Both the PPARγ ligands and the Cox-2
Publikováno v:
Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti. 27
Apoptosis is type I programmed cell death, a process that is essential for development and tissue homeostasis. It is a prevalent form of cell death and it proceeds via two signaling pathways - external (receptor pathway) triggered by death receptors
Autor:
Lucia Knopfová, Miroslav Fojta, Diana Pinheiro, Filip Trčka, Karel Souček, Petr Beneš, Alice Nemajerova, Jan Šmarda
Publikováno v:
Cancer letters. 303(1)
The naturally occurring coumestan wedelolactone has been previously shown to reduce growth of various cancer cells. So far, the growth-suppressing effect of wedelolactone has been attributed to the inhibition of the NFκB transcription factor and/or