Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Katri Koli"'
Autor:
Mayank Saraswat, Katri Koli, Eva Sutinen, Risto Renkonen, Ville Vartiainen, Tiialotta Tohmola, Sakari Joenväärä, Marjukka Myllärniemi
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Idiopathic pulmonary fibrosis (IPF) is a lung parenchymal disease of unknown cause usually occurring in older adults. It is a chronic and progressive condition with poor prognosis and diagnosis is largely clinical. Currently, there exist few biomarke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29b996f2c5dcb8f759df60cdde4923f3
http://hdl.handle.net/10138/319352
http://hdl.handle.net/10138/319352
Autor:
Norbert Weissmann, Susan Scheibe, Katri Koli, Harald von Melchner, Martin Serchinger, Ana Tomasovic, Silke De-Zolt, Duran Sürün, Anja Sterner-Kock, Nina Kurrle, Frank Schnütgen, Frank Wempe
Publikováno v:
Matrix Biology. 59:109-120
Latent transforming growth factor beta binding protein 4 (LTBP4) belongs to the fibrillin/LTBP family of proteins and plays an important role as a structural component of extracellular matrix (ECM) and local regulator of TGF beta signaling. We have p
Autor:
Ville Vartiainen, Katri Koli, Veronika Rezov, Emmi I. Joensuu, Chang Li, Mikko Rönty, Miao Yin, Marjukka Myllärniemi
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Malignant mesothelioma is an aggressive cancer with poor prognosis. It is characterized by prominent extracellular matrix, mesenchymal tumor cell phenotypes and chemoresistance. In this study, the ability of pirfenidone to alter mesothelioma cell pro
Publikováno v:
Molecular Endocrinology. 29:1787-1791
Recently, several LH/human chorionic gonadotropin (hCG) receptor-independent activities for hCG have been described, including activation of the TGF-β receptor (TGFβR) by hyperglycosylated hCG and stimulation of trophoblast invasion. Because the hC
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 48:448-455
Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease with a poor prognosis and very few therapeutic options. On the molecular level, patients with IPF have increased amounts of the bone morphogenetic protein (BMP) inhibitor gremlin in th
Publikováno v:
Antioxidants & Redox Signaling. 10:333-342
Transforming growth factor-betas (TGF-beta) regulate a wide variety of cellular functions in normal development and are involved in both tissue homeostasis and disease pathogenesis. The regulation of the TGF-beta family of growth factors is unique be
Autor:
Kaisa Salmenkivi, Kirsi Vuorinen, Merja Johanna Ryynänen, Katri Koli, Vuokko L. Kinnula, Jorma Keski-Oja, Marjukka Myllärniemi
Publikováno v:
The American Journal of Pathology. 169:61-71
Idiopathic pulmonary fibrosis (IPF), ie, usual interstitial pneumonia in histopathology, is a disease characterized by tissue destruction and active areas of fibroproliferation in the lung. Gremlin (Drm), a member of the cysteine knot family of bone
Autor:
Katharina Kuhlmeier, Irmgard S. Thorey, Frank Wempe, Katri Koli, Thomas Kirchner, Jürgen Otte, Harald von Melchner, Thorsten Bangsow, Jorma Keski-Oja, Shenchu Jin, Anja Sterner-Kock
Publikováno v:
Genes & Development. 16:2264-2273
Transforming growth factor-βs (TGF-βs) are multifunctional growth factors that are secreted as inactive (latent) precursors in large protein complexes. These complexes include the latency-associated propeptide (LAP) and a latent transforming growth
Autor:
Hongqiang Ma, Arja Pasternack, Katri Koli, Olli Ritvos, Jussi Tikkanen, Juha J. Hulmi, Outi Leppäranta, Marjukka Myllärniemi, Mikko Rönty, Eva Sutinen
Publikováno v:
BMC Pulmonary Medicine
Background: Activins are members of the TGF-ß superfamily of growth factors. First, we identified by expression array screening that activin-B and follistatin are upregulated in human idiopathic pulmonary fibrosis (IPF). Next, we wanted to clarify t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcb2584007498131227e463a929c3b60
http://urn.fi/URN:NBN:fi:jyu-201412083448
http://urn.fi/URN:NBN:fi:jyu-201412083448
Autor:
Liisa Lilja-Maula, Katri Koli, Eva Sutinen, Pernilla Syrjä, Mikko Rönty, HP Laurila, Marjukka Myllärniemi, Minna M. Rajamäki
Publikováno v:
Journal of comparative pathology. 150(4)
Activation of transforming growth factor (TGF)-β is a key event in the progression of fibrosis in human lung tissue. Idiopathic pulmonary fibrosis (IPF) in West Highland white terriers (WHWTs) shares histopathological features of human usual interst