Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Guosheng Fu"'
Publikováno v:
International Journal of Molecular Medicine
Thrombospondin (TSP)‑1 and TSP‑2 are matricellular proteins in the extracellular matrix (ECM), which serve a significant role in the pathological processes of various cardiovascular diseases (CVDs). The multiple effects of TSP‑1 and TSP‑2 are
Autor:
Wen-Bin Zhang, Zhida Shen, Jian Ji, Ke-feng Ren, Jing Wang, Shengyu Chen, Youxiang Wang, Fan Jia, Guosheng Fu
Publikováno v:
Journal of materials chemistry. B. 10(14)
Thrombus and restenosis after stent implantation are the major complications because traditional drugs such as rapamycin delay the process of endothelialization. Nitric oxide (NO) is mainly produced by endothelial nitric oxide synthase (eNOS) on the
Publikováno v:
Cell biology internationalREFERENCES. 45(7)
Farnesyl pyrophosphate synthase (FPPS)-catalyzed isoprenoid intermediates are involved in diabetic cardiomyopathy. This study investigated the specific role of FPPS in the development of diabetic cardiomyopathy. We demonstrated that FPPS expression w
Publikováno v:
Biochemical and biophysical research communications. 528(3)
Myocardial ischemia/reperfusion (MI/R) injury, a complicated pathophysiological process, is regulated by lots of signaling pathways. Here in our present study, we identified TANK-binding kinase 1 (TBK1), an IKK-related serine/threonine kinase, as a p
Autor:
Guosheng Fu, Yao Wang, Wenbin Zhang, Ya Li, Qingbo Lv, Meihui Wang, Liding Zhao, Yingchao Gong, Min Wang
Publikováno v:
Journal of Cardiovascular Pharmacology
Vascular remodeling is one of the most critical complications caused by hypertension. Previous studies have demonstrated that rosuvastatin has anti-inflammatory, antioxidant, and antiplatelet effects and therefore can be used to treat cardiovascular
Publikováno v:
BMC Cardiovascular Disorders
BMC Cardiovascular Disorders, Vol 19, Iss 1, Pp 1-7 (2019)
BMC Cardiovascular Disorders, Vol 19, Iss 1, Pp 1-7 (2019)
Background Ticagrelor and clopidogrel, P2Y12 receptor antagonists, can prevent thrombotic events and are used to treat cardiovascular diseases such as acute coronary syndrome and chronic obstructive pulmonary disease, in which inflammation is involve
Publikováno v:
Cell Biology International. 41:1146-1159
The objective of the research was to investigate the function of endothelial progenitor cells (EPCs) in the conditions of high glucose and lipids, which has been widely used to mimic the metabolic disorder that occurs in type 2 diabetic mellitus, and
Autor:
Qingyuan Yang, Xianglan Liu, Tuo Huang, Yong Sun, Song Sun, Jing Li, Guosheng Fu, Ying Liu, Nan Gu, Jian Wu, Shufeng Li, Hui Dong, Yang Yi, Bo Yu
Publikováno v:
Journal of cellular physiologyREFERENCES. 236(3)
The long noncoding RNA antisense noncoding RNA in the INK4 locus (ANRIL) plays a critical role in the development of atherosclerosis. However, the precise effect of ANRIL on endothelial dysfunction remains unclear. In this study, we investigated ANRI
Publikováno v:
Cellular and molecular biology (Noisy-le-Grand, France). 65(4)
Endothelial progenitor cells (EPCs) improve neovascularization and endothelium regeneration. Transplantation with EPCs is a therapeutic strategy for the treatment of ischemic diseases. However, the transplanted EPCs are susceptible to adverse environ
Publikováno v:
Anatolian Journal of Cardiology
Objective To investigate the effects of advanced glycation end products (AGEs) on the proliferation and apoptosis of cardiac microvascular endothelial cells (CMECs) in rats and their underlying signaling pathway. Methods CMECs were isolated from Spra