Zobrazeno 1 - 10
of 26
pro vyhledávání: '"John M. Hickey"'
Autor:
Sungbong Jang, Roger Ros-Freixedes, John M. Hickey, Ching-Yi Chen, Justin Holl, William O. Herring, Ignacy Misztal, Daniela Lourenco
Publikováno v:
Genetics Selection Evolution, Vol 55, Iss 1, Pp 1-14 (2023)
Abstract Background Whole-genome sequence (WGS) data harbor causative variants that may not be present in standard single nucleotide polymorphism (SNP) chip data. The objective of this study was to investigate the impact of using preselected variants
Externí odkaz:
https://doaj.org/article/28cdcd2260864b89960a349718dc62ee
Autor:
Suzanne Desire, Martin Johnsson, Roger Ros-Freixedes, Ching-Yi Chen, Justin W. Holl, William O. Herring, Gregor Gorjanc, Richard J. Mellanby, John M. Hickey, Melissa K. Jungnickel
Publikováno v:
Genetics Selection Evolution, Vol 55, Iss 1, Pp 1-13 (2023)
Abstract Background Genome-wide association studies (GWAS) aim at identifying genomic regions involved in phenotype expression, but identifying causative variants is difficult. Pig Combined Annotation Dependent Depletion (pCADD) scores provide a meas
Externí odkaz:
https://doaj.org/article/6256dd90e214432991a89312e92ec1cc
Autor:
Roger Ros-Freixedes, Martin Johnsson, Andrew Whalen, Ching-Yi Chen, Bruno D. Valente, William O. Herring, Gregor Gorjanc, John M. Hickey
Publikováno v:
Genetics Selection Evolution, Vol 54, Iss 1, Pp 1-18 (2022)
Abstract Background Early simulations indicated that whole-genome sequence data (WGS) could improve the accuracy of genomic predictions within and across breeds. However, empirical results have been ambiguous so far. Large datasets that capture most
Externí odkaz:
https://doaj.org/article/8bad4d76ab95401eae3fa70898f1c7b0
Autor:
Roger Ros-Freixedes, Bruno D. Valente, Ching-Yi Chen, William O. Herring, Gregor Gorjanc, John M. Hickey, Martin Johnsson
Publikováno v:
Genetics Selection Evolution, Vol 54, Iss 1, Pp 1-16 (2022)
Abstract Background It is expected that functional, mainly missense and loss-of-function (LOF), and regulatory variants are responsible for most phenotypic differences between breeds and genetic lines of livestock species that have undergone diverse
Externí odkaz:
https://doaj.org/article/2a7e0249ae5c4d0a9f3144f43aca40a7
Autor:
Christos Dadousis, Adriana Somavilla, Joanna J. Ilska, Martin Johnsson, Lorena Batista, Richard J. Mellanby, Denis Headon, Paolo Gottardo, Andrew Whalen, David Wilson, Ian C. Dunn, Gregor Gorjanc, Andreas Kranis, John M. Hickey
Publikováno v:
Genetics Selection Evolution, Vol 53, Iss 1, Pp 1-14 (2021)
Abstract Background Body weight (BW) is an economically important trait in the broiler (meat-type chickens) industry. Under the assumption of polygenicity, a “large” number of genes with “small” effects is expected to control BW. To detect su
Externí odkaz:
https://doaj.org/article/af5cc1d8be434c6fb74eecfdab9242b5
Autor:
Miguel Gozalo-Marcilla, Jaap Buntjer, Martin Johnsson, Lorena Batista, Federico Diez, Christian R. Werner, Ching-Yi Chen, Gregor Gorjanc, Richard J. Mellanby, John M. Hickey, Roger Ros-Freixedes
Publikováno v:
Genetics Selection Evolution, Vol 53, Iss 1, Pp 1-14 (2021)
Abstract Background Backfat thickness is an important carcass composition trait for pork production and is commonly included in swine breeding programmes. In this paper, we report the results of a large genome-wide association study for backfat thick
Externí odkaz:
https://doaj.org/article/8aaaf37f2a6146eca9c830048c246bd8
Autor:
Martin Johnsson, Andrew Whalen, Roger Ros-Freixedes, Gregor Gorjanc, Ching-Yi Chen, William O. Herring, Dirk-Jan de Koning, John M. Hickey
Publikováno v:
Genetics Selection Evolution, Vol 53, Iss 1, Pp 1-19 (2021)
Abstract Background Meiotic recombination results in the exchange of genetic material between homologous chromosomes. Recombination rate varies between different parts of the genome, between individuals, and is influenced by genetics. In this paper,
Externí odkaz:
https://doaj.org/article/698734515d3c4f3a93b1ec7156f71bd2
Publikováno v:
Genetics Selection Evolution, Vol 53, Iss 1, Pp 1-11 (2021)
Abstract Background In this paper, we present the AlphaPart R package, an open-source implementation of a method for partitioning breeding values and genetic trends to identify the contribution of selection pathways to genetic gain. Breeding programm
Externí odkaz:
https://doaj.org/article/bb4b0944d1d547f0b50f20df456618ae
Publikováno v:
Genetics Selection Evolution, Vol 52, Iss 1, Pp 1-17 (2020)
Abstract Background Breeders and geneticists use statistical models to separate genetic and environmental effects on phenotype. A common way to separate these effects is to model a descriptor of an environment, a contemporary group or herd, and accou
Externí odkaz:
https://doaj.org/article/490e8d20fe91411fb9907d5caafbafda
Autor:
Daniel Money, David Wilson, Janez Jenko, Andrew Whalen, Steve Thorn, Gregor Gorjanc, John M. Hickey
Publikováno v:
Genetics Selection Evolution, Vol 52, Iss 1, Pp 1-12 (2020)
Abstract Background We describe the latest improvements to the long-range phasing (LRP) and haplotype library imputation (HLI) algorithms for successful phasing of both datasets with one million individuals and datasets genotyped using different sets
Externí odkaz:
https://doaj.org/article/6636377e65384c16bd7a2cd56a918d0d