Zobrazeno 1 - 10
of 232
pro vyhledávání: '"Yan Cheng"'
Autor:
Sheng Gao, Lingling Wang, Fei Sun, C. Yan Cheng, Liwei Zhou, Tiao Bu, Siwen Wu, Xiaolong Wu, Jie Shi, Di Wu
Publikováno v:
Seminars in Cell & Developmental Biology. 121:125-132
Studies have demonstrated that biologically active fragments are generated from the basement membrane and the Sertoli cell-spermatid adhesion site known as apical ectoplasmic specialization (apical ES, a testis-specific actin-based anchoring junction
Autor:
C. Yan Cheng, Chris K C Wong, Xiaolong Wu, Lingling Wang, Adolfo Perrotta, Bruno Silvestrini, Fei Sun, Linxi Li
Publikováno v:
Seminars in Cell & Developmental Biology. 121:53-62
In rodents and humans, the major cellular events at spermatogenesis include self-renewal of spermatogonial stem cells and undifferentiated spermatogonia via mitosis, commitment of spermatogonia to differentiation and transformation to spermatocytes,
Publikováno v:
Critical Reviews in Biochemistry and Molecular Biology. 56:236-254
It is almost five decades since the discovery of the hypothalamic-pituitary-testicular axis. This refers to the hormonal axis that connects the hypothalamus, pituitary gland and testes, which in turn, regulates the production of spermatozoa through s
Autor:
C. Yan Cheng, Xiaolong Wu, Fei Sun, Ming Yan, Lingling Wang, Siwen Wu, Ren-Shan Ge, Chris K C Wong, Tiao Bu
Publikováno v:
Reproductive Toxicology. 96:76-89
Actin cytoskeleton is crucial to support spermatogenesis in the mammalian testis. However, the molecular mechanism(s) underlying changes of actin cytoskeletal organization in response to cellular events that take place across the seminiferous epithel
Autor:
Fei Sun, C. Yan Cheng, Siwen Wu, Baiping Mao, Ren-Shan Ge, Chris K C Wong, Ming Yan, Lingling Wang
Publikováno v:
Toxicol Sci
Studies have shown that mammalian testes, in particular the Sertoli cells, are highly susceptible to exposure of environmental toxicants, such as cadmium, perfluorooctanesulfonate, phthalates, 2,5-hexanedione and bisphenol A. However, important studi
Publikováno v:
Trends in Molecular Medicine. 26:215-231
Spermatogenesis is supported by intricate crosstalk between Sertoli cells and germ cells including spermatogonia, spermatocytes, haploid spermatids, and spermatozoa, which takes place in the epithelium of seminiferous tubules. Sertoli cells, also kno
Publikováno v:
Reproductive Toxicology. 91:43-52
During spermatogenesis, preleptotene spermatocytes and haploid spermatids, lacking lamellipodia and filopodia to initiate cell movement per se, but rely on Sertoli cells for transport across the blood-testis barrier (BTB) and the adluminal compartmen
Publikováno v:
The FASEB Journal. 35
In mammalian testes, extensive remodeling of the microtubule (MT) and actin cytoskeletons takes place in Sertoli cells across the seminiferous epithelium to support spermatogenesis. However, the mechanism(s) involving regulatory and signaling protein
Publikováno v:
Endocrinology
Studies suggest that HIV-1 invades the testis through initial permeation of the blood–testis barrier (BTB). The selectivity of the BTB to antiretroviral drugs makes this site a sanctuary for the virus. Little is known about how HIV-1 crosses the BT
Publikováno v:
Toxicological Sciences. 172:75-88
During spermatogenesis, cell organelles, and germ cells, most notably haploid spermatids, are transported across the seminiferous epithelium so that fully developed spermatids line-up at the edge of the tubule lumen to undergo spermiation at stage VI