Zobrazeno 1 - 10
of 36
pro vyhledávání: '"A Laustsen"'
Autor:
Cecilie Knudsen, Jonas A. Jürgensen, Pelle D. Knudsen, Irina Oganesyan, Julian A. Harrison, Søren H. Dam, Aleksander M. Haack, Rasmus U.W. Friis, Lars Vitved, Selma B. Belfakir, Georgina M.S. Ross, Renato Zenobi, Andreas H. Laustsen
Publikováno v:
Knudsen, C, Jürgensen, J A, D. Knudsen, P, Oganesyan, I, Harrison, J A, Dam, S H, Haack, A M, Friis, R U W, Vitved, L, Belfakir, S B, Ross, G M S, Zenobi, R & H. Laustsen, A 2023, ' Prototyping of a lateral flow assay based on monoclonal antibodies for detection of Bothrops venoms ', Analytica Chimica Acta, vol. 1272, 341306 . https://doi.org/10.1016/j.aca.2023.341306
Analytica Chimica Acta, 1272
Analytica Chimica Acta, 1272
Background: Brazil is home to a multitude of venomous snakes; perhaps the most medically relevant of which belong to the Bothrops genus. Bothrops spp. are responsible for roughly 70% of all snakebites in Brazil, and envenomings caused by their bites
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4072e5f82fc18bf4d0fc2db724b9c140
https://orbit.dtu.dk/en/publications/dd638f27-e7e3-4576-99a3-94aff4c25dd1
https://orbit.dtu.dk/en/publications/dd638f27-e7e3-4576-99a3-94aff4c25dd1
Autor:
Sørensen, Christoffer V., Ledsgaard, Line, Wildenauer, Helen H. K., Dahl, Camilla H., Ebersole, Tasja W., Bohn, Markus-Frederik, Ljungars, Anne, Jenkins, Timothy P., Laustsen, Andreas H.
Publikováno v:
Sørensen, C V, Ledsgaard, L, Wildenauer, H H K, Dahl, C H, Ebersole, T W, Bohn, M-F, Ljungars, A, Jenkins, T P & Laustsen, A H 2023, ' Cross-reactivity trends when selecting scFv antibodies against snake toxins using a phage display-based cross-panning strategy ', Scientific Reports, vol. 13, 10181 . https://doi.org/10.1038/s41598-023-37056-6
Antibodies with cross-reactive binding and broad toxin-neutralizing capabilities are advantageous for treating indications such as infectious diseases and animal envenomings. Such antibodies have been successfully selected against closely related ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1202::adc028f025bf411fc81462b47055653b
https://orbit.dtu.dk/en/publications/6f3f09fb-2aa1-40fc-bfa2-dd409bcfab92
https://orbit.dtu.dk/en/publications/6f3f09fb-2aa1-40fc-bfa2-dd409bcfab92
Autor:
Sanchez-Heredia, Juan D., Olin, Rie B., Grist, James T., Wang, Wenjun, Bøgh, Nikolaj, Zhurbenko, Vitaliy, Hansen, Esben S., Schulte, Rolf F., Tyler, Damian, Laustsen, Christoffer, Ardenkjær-Larsen, Jan H.
Publikováno v:
Sanchez-Heredia, J D, Olin, R B, Grist, J T, Wang, W, Bøgh, N, Zhurbenko, V, Hansen, E S, Schulte, R F, Tyler, D, Laustsen, C & Ardenkjaer-Larsen, J H 2022, ' RF coil design for accurate parallel imaging on 13 C MRSI using 23 Na sensitivity profiles ', Magnetic Resonance in Medicine, vol. 88, no. 3, pp. 1391-1405 . https://doi.org/10.1002/mrm.29259
Sanchez-Heredia, J D, Olin, R B, Grist, J T, Wang, W, Bøgh, N, Zhurbenko, V, Hansen, E S, Schulte, R F, Tyler, D, Laustsen, C & Ardenkjær-Larsen, J H 2022, ' RF coil design for accurate parallel imaging on 13 C MRSI using 23 Na sensitivity profiles ', Magnetic Resonance in Medicine, vol. 88, no. 3, pp. 1391-1405 . https://doi.org/10.1002/mrm.29259
Sanchez-Heredia, J D, Olin, R B, Grist, J T, Wang, W, Bøgh, N, Zhurbenko, V, Hansen, E S, Schulte, R F, Tyler, D, Laustsen, C & Ardenkjær-Larsen, J H 2022, ' RF coil design for accurate parallel imaging on 13 C MRSI using 23 Na sensitivity profiles ', Magnetic Resonance in Medicine, vol. 88, no. 3, pp. 1391-1405 . https://doi.org/10.1002/mrm.29259
Purpose: To develop a coil-based method to obtain accurate sensitivity profiles in 13C MRI at 3T from the endogenous 23Na. An eight-channel array is designed for 13C MR acquisitions. As application examples, the array is used for two-fold accelerated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::8c35a5da5120905f50970ea52099f7dd
https://pure.au.dk/portal/da/publications/rf-coil-design-for-accurate-parallel-imaging-on-13c-mrsi-using-23na-sensitivity-profiles(105be123-39d7-4dce-9ec3-9ace75a2b5cd).html
https://pure.au.dk/portal/da/publications/rf-coil-design-for-accurate-parallel-imaging-on-13c-mrsi-using-23na-sensitivity-profiles(105be123-39d7-4dce-9ec3-9ace75a2b5cd).html
Autor:
Shirin Ahmadi, Spyridon T. Pachis, Konstantinos Kalogeropoulos, Farrell McGeoghan, Vahap Canbay, Steven R. Hall, Edouard P. Crittenden, Charlotte A. Dawson, Keirah E. Bartlett, José María Gutiérrez, Nicholas R. Casewell, Ulrich auf dem Keller, Andreas H. Laustsen
Publikováno v:
Ahmadi, S, Pachis, S T, Kalogeropoulos, K, McGeoghan, F, Canbay, V, Hall, S R, Crittenden, E P, Dawson, C A, Bartlett, K E, Gutiérrez, J M, Casewell, N R, Keller, U A D & Laustsen, A H 2022, ' Proteomics and histological assessment of an organotypic model of human skin following exposure to Naja nigricollis venom ', Toxicon, vol. 220, 12 . https://doi.org/10.1016/j.toxicon.2022.106955
Snakebite envenoming was reintroduced as a Category A Neglected Tropical Disease by the World Health Organization in 2017. Since then, increased attention has been directed towards this affliction and towards the development of a deeper understanding
Autor:
Berthe Katrine Fiil, Sandra Wingaard Thrane, Michael Pichler, Tiia Kittilä, Line Ledsgaard, Shirin Ahmadi, Grith Miriam Maigaard Hermansen, Lars Jelsbak, Charlotte Lauridsen, Susanne Brix, Andreas Hougaard Laustsen
Publikováno v:
Fiil, B K, Thrane, S W, Pichler, M, Kittilä, T, Ledsgaard, L, Ahmadi, S, Hermansen, G M M, Jelsbak, L, Lauridsen, C, Brix, S & Laustsen, A H 2022, ' Orally active bivalent V H H construct prevents proliferation of F4 + enterotoxigenic Escherichia coli in weaned piglets ', iScience, vol. 25, no. 4, 104003 . https://doi.org/10.1016/j.isci.2022.104003
A major challenge in industrial pig production is the prevalence of post-weaning diarrhea (PWD) in piglets, often caused by enterotoxigenic Escherichia coli (ETEC). The increased use of antibiotics and zinc oxide to treat PWD has raised global concer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a4312e2a6b48aa66fc959035f90dd85
https://orbit.dtu.dk/en/publications/fb2da6e0-9b1c-4ba9-98e2-a4be914191ec
https://orbit.dtu.dk/en/publications/fb2da6e0-9b1c-4ba9-98e2-a4be914191ec
Autor:
Wei-qiao Rao, Konstantinos Kalogeropoulos, Morten E Allentoft, Shyam Gopalakrishnan, Wei-ning Zhao, Christopher T Workman, Cecilie Knudsen, Belén Jiménez-Mena, Lorenzo Seneci, Mahsa Mousavi-Derazmahalleh, Timothy P Jenkins, Esperanza Rivera-de-Torre, Si-qi Liu, Andreas H Laustsen
Publikováno v:
Rao, W Q, Kalogeropoulos, K, Allentoft, M E, Gopalakrishnan, S, Zhao, W, Workman, C T, Knudsen, C, Jiménez-Mena, B, Seneci, L, Mousavi-Derazmahalleh, M, Jenkins, T P, Rivera-de-Torre, E, Liu, S Q & Laustsen, A H 2022, ' The rise of genomics in snake venom research : recent advances and future perspectives ', GigaScience, vol. 11, giac024 . https://doi.org/10.1093/gigascience/giac024
Rao, W-Q, Kalogeropoulos, K, Allentoft, M E, Gopalakrishnan, S, Zhao, W-N, Workman, C T, Knudsen, C, Jiménez-Mena, B, Seneci, L, Mousavi-Derazmahalleh, M, Jenkins, T P, Rivera-de-Torre, E, Liu, S-Q & Laustsen, A H 2022, ' The rise of genomics in snake venom research: recent advances and future perspectives ', GigaScience, vol. 11, giac024 . https://doi.org/10.1093/gigascience/giac024
GigaScience
Rao, W-Q, Kalogeropoulos, K, Allentoft, M E, Gopalakrishnan, S, Zhao, W-N, Workman, C T, Knudsen, C, Jiménez-Mena, B, Seneci, L, Mousavi-Derazmahalleh, M, Jenkins, T P, Rivera-de-Torre, E, Liu, S-Q & Laustsen, A H 2022, ' The rise of genomics in snake venom research: recent advances and future perspectives ', GigaScience, vol. 11, giac024 . https://doi.org/10.1093/gigascience/giac024
GigaScience
Snake venoms represent a danger to human health, but also a gold mine of bioactive proteins that can be harnessed for drug discovery purposes. The evolution of snakes and their venom has been studied for decades, particularly via traditional morpholo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7089b39d4f308e27b2e8bdc763252f4c
https://curis.ku.dk/ws/files/311599953/giac024.pdf
https://curis.ku.dk/ws/files/311599953/giac024.pdf
Autor:
Jeroen Kool, Nafiseh Nasri Nasrabadi, Melissa Hale, Mátyás A. Bittenbinder, Shirin Ahmadi, Darian S Wolff, Andreas Hougaard Laustsen, Timothy P. Jenkins, Freek J. Vonk, Dilber E Akgun, Trenton K Stewart
Publikováno v:
PLoS Neglected Tropical Diseases
Jenkins, T P, Ahmadi, S, Bittenbinder, M A, Stewart, T K, Akgun, D E, Hale, M, Nasrabadi, N N, Wolff, D S, Vonk, F J, Kool, J & Laustsen, A H 2021, ' Terrestrial venomous animals, the envenomings they cause, and treatment perspectives in the Middle East and North Africa ', PLOS Neglected Tropical Diseases, vol. 15, no. 12, e0009880 . https://doi.org/10.1371/journal.pntd.0009880
PLOS Neglected Tropical Diseases
Jenkins, T P, Ahmadi, S, Bittenbinder, M A, Stewart, T K, Akgun, D E, Hale, M, Nasrabadi, N N, Wolff, D S, Vonk, F J, Kool, J & Laustsen, A H 2021, ' Terrestrial venomous animals, the envenomings they cause, and treatment perspectives in the middle east and North Africa ', PLoS Neglected Tropical Diseases, vol. 15, no. 12, e0009880, pp. 1-36 . https://doi.org/10.1371/journal.pntd.0009880
PLoS Neglected Tropical Diseases, Vol 15, Iss 12, p e0009880 (2021)
Jenkins, T P, Ahmadi, S, Bittenbinder, M A, Stewart, T K, Akgun, D E, Hale, M, Nasrabadi, N N, Wolff, D S, Vonk, F J, Kool, J & Laustsen, A H 2021, ' Terrestrial venomous animals, the envenomings they cause, and treatment perspectives in the Middle East and North Africa ', PLOS Neglected Tropical Diseases, vol. 15, no. 12, e0009880 . https://doi.org/10.1371/journal.pntd.0009880
PLOS Neglected Tropical Diseases
Jenkins, T P, Ahmadi, S, Bittenbinder, M A, Stewart, T K, Akgun, D E, Hale, M, Nasrabadi, N N, Wolff, D S, Vonk, F J, Kool, J & Laustsen, A H 2021, ' Terrestrial venomous animals, the envenomings they cause, and treatment perspectives in the middle east and North Africa ', PLoS Neglected Tropical Diseases, vol. 15, no. 12, e0009880, pp. 1-36 . https://doi.org/10.1371/journal.pntd.0009880
PLoS Neglected Tropical Diseases, Vol 15, Iss 12, p e0009880 (2021)
The Middle East and Northern Africa, collectively known as the MENA region, are inhabited by a plethora of venomous animals that cause up to 420,000 bites and stings each year. To understand the resultant health burden and the key variables affecting
Autor:
Andreas Hougaard Laustsen, Manuela Berto Pucca, Christoffer V. Sørensen, Figen Caliskan, Rahel Janke, Line Ledsgaard, Erwin M. Schoof, Jonas A. Jürgensen, Shirin Ahmadi
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-7 (2020)
Scientific Reports
Ahmadi, S, Pucca, M B, Jürgensen, J A, Janke, R, Ledsgaard, L, Schoof, E M, Sørensen, C V, Çalışkan, F & Laustsen, A H 2020, ' An in vitro methodology for discovering broadly-neutralizing monoclonal antibodies ', Scientific Reports, vol. 10, no. 1, 10765 . https://doi.org/10.1038/s41598-020-67654-7
Scientific Reports
Ahmadi, S, Pucca, M B, Jürgensen, J A, Janke, R, Ledsgaard, L, Schoof, E M, Sørensen, C V, Çalışkan, F & Laustsen, A H 2020, ' An in vitro methodology for discovering broadly-neutralizing monoclonal antibodies ', Scientific Reports, vol. 10, no. 1, 10765 . https://doi.org/10.1038/s41598-020-67654-7
Broadly-neutralizing monoclonal antibodies are of high therapeutic utility against infectious diseases caused by bacteria and viruses, as well as different types of intoxications. Snakebite envenoming is one such debilitating pathology, which is curr
Autor:
Lisa Gregersen Oestergaard, Annemette Krintel Petersen, Sussie Laustsen, Maurits W. van Tulder
Publikováno v:
Clinical Rehabilitation, 34(1), 69-81. SAGE Publications Ltd
Petersen, A K, Oestergaard, L G, van Tulder, M & Laustsen, S 2020, ' A comparison of high versus low dose of exercise training in exercise-based cardiac rehabilitation : a randomized controlled trial with 12-months follow-up ', Clinical Rehabilitation, vol. 34, no. 1, pp. 69-81 . https://doi.org/10.1177/0269215519883411
Petersen, A K, Oestergaard, L G, van Tulder, M & Laustsen, S 2020, ' A comparison of high versus low dose of exercise training in exercise-based cardiac rehabilitation : a randomized controlled trial with 12-months follow-up ', Clinical Rehabilitation, vol. 34, no. 1, 0269215519883411, pp. 69-81 . https://doi.org/10.1177/0269215519883411
Petersen, A K, Oestergaard, L G, van Tulder, M & Laustsen, S 2020, ' A comparison of high versus low dose of exercise training in exercise-based cardiac rehabilitation : a randomized controlled trial with 12-months follow-up ', Clinical Rehabilitation, vol. 34, no. 1, pp. 69-81 . https://doi.org/10.1177/0269215519883411
Petersen, A K, Oestergaard, L G, van Tulder, M & Laustsen, S 2020, ' A comparison of high versus low dose of exercise training in exercise-based cardiac rehabilitation : a randomized controlled trial with 12-months follow-up ', Clinical Rehabilitation, vol. 34, no. 1, 0269215519883411, pp. 69-81 . https://doi.org/10.1177/0269215519883411
Objective: To assess if a higher dose of exercise training in exercise-based cardiac rehabilitation could affect improvements in aerobic capacity and muscle strength. Design: Assessor-blinded randomized controlled trial with 12-months follow-up. Sett
Autor:
Annemette Krintel Petersen, Vibeke E. Hjortdal, Sussie Laustsen, Maurits W. van Tulder, Lisa Gregersen Oestergaard
Publikováno v:
Laustsen, S, Østergaard, L G, Van Tulder, M, Hjortdal, V E & Petersen, A K 2020, ' Telemonitored exercise-based cardiac rehabilitation improves physical capacity and health-related quality of life ', Journal of Telemedicine and Telecare, vol. 26, no. 1-2, pp. 36-44 . https://doi.org/10.1177/1357633X18792808
Laustsen, S, Oestergaard, L G, van Tulder, M, Hjortdal, V E & Petersen, A K 2020, ' Telemonitored exercise-based cardiac rehabilitation improves physical capacity and health-related quality of life ', Journal of Telemedicine and Telecare, vol. 26, no. 1-2, pp. 36-44 . https://doi.org/10.1177/1357633X18792808
Journal of Telemedicine and Telecare, 26(1-2), 36-44. SAGE Publications Ltd
Laustsen, S, Oestergaard, L G, van Tulder, M, Hjortdal, V E & Petersen, A K 2020, ' Telemonitored exercise-based cardiac rehabilitation improves physical capacity and health-related quality of life ', Journal of Telemedicine and Telecare, vol. 26, no. 1-2, pp. 36-44 . https://doi.org/10.1177/1357633X18792808
Journal of Telemedicine and Telecare, 26(1-2), 36-44. SAGE Publications Ltd
Introduction Cardiac rehabilitation improves physical capacity, health-related quality of life, and reduces morbidity and mortality among cardiac patients. Telemonitored exercise-based cardiac rehabilitation may innovate existing programmes and incre