Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Alberto Estevez"'
Autor:
Stefan Gerhardy, Mark Ultsch, Wanjian Tang, Evan Green, Jeffrey K. Holden, Wei Li, Alberto Estevez, Chris Arthur, Irene Tom, Alexis Rohou, Daniel Kirchhofer
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
The protease HTRA1 is a genetic risk factor for geographic atrophy. Here, Gerhardy et al. describe its inhibition by a clinical Fab, whose binding locks it in an inactive state. The mechanism identifies an essential function of LoopA with this protea
Externí odkaz:
https://doaj.org/article/55461e6817b145b7b4f3d1b202ec723c
Autor:
Henry R. Maun, Rajesh Vij, Benjamin T. Walters, Ashley Morando, Janet K. Jackman, Ping Wu, Alberto Estevez, Xiaocheng Chen, Yvonne Franke, Michael T. Lipari, Mark S. Dennis, Daniel Kirchhofer, Claudio Ciferri, Kelly M. Loyet, Tangsheng Yi, Charles Eigenbrot, Robert A. Lazarus, James T. Koerber
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
β-tryptases are responsible for most of the proteolytic activity during mast cell activation. Here, the authors develop β-tryptase-inhibiting antibodies and provide structural and biochemical evidence that the bivalency of the antibodies is a prere
Externí odkaz:
https://doaj.org/article/731be2a1b0e94f0d9e6e6bb1c65b39da
Autor:
Ning Chai, Lee R. Swem, Summer Park, Gerald Nakamura, Nancy Chiang, Alberto Estevez, Rina Fong, Lynn Kamen, Elviza Kho, Mike Reichelt, Zhonghua Lin, Henry Chiu, Elizabeth Skippington, Zora Modrusan, Jeremy Stinson, Min Xu, Patrick Lupardus, Claudio Ciferri, Man-Wah Tan
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-18 (2017)
Influenza B virus (IBV) co-circulates with influenza A virus to cause annual epidemics. Here, Chaiet al. isolate a human monoclonal antibody that binds to a conserved epitope in the viral HA protein, neutralizes IBV strains in vitro, and protects mic
Externí odkaz:
https://doaj.org/article/d697ead9ca194b4d8f53f1f10eadf047
Autor:
Ning Chai, Lee R. Swem, Summer Park, Gerald Nakamura, Nancy Chiang, Alberto Estevez, Rina Fong, Lynn Kamen, Elviza Kho, Mike Reichelt, Zhonghua Lin, Henry Chiu, Elizabeth Skippington, Zora Modrusan, Jeremy Stinson, Min Xu, Patrick Lupardus, Claudio Ciferri, Man-Wah Tan
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-2 (2017)
Nature Communications 8: Article number: 14234 (2017); Published: 19 January 2017; Updated: 25 May 2017 This Article contains errors in Fig. 5c. The blue squares should be labelled ‘Water+46B8’ and the green triangles should be labelled ‘Tamifl
Externí odkaz:
https://doaj.org/article/fd4f9823a247424798f021121a6f98cd
Autor:
Henry Chiu, Elviza Kho, Lee R. Swem, Elizabeth Skippington, Man-Wah Tan, Zora Modrusan, Gerald R. Nakamura, Min Xu, Zhonghua Lin, Claudio Ciferri, Mike Reichelt, Rina Fong, Summer Park, Lynn Kamen, Nan Chiang, Patrick J. Lupardus, Jeremy Stinson, Alberto Estevez, Ning Chai
Publikováno v:
Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-18 (2017)
Nature Communications, Vol 8, Iss 1, Pp 1-18 (2017)
Influenza B virus (IBV) causes annual influenza epidemics around the world. Here we use an in vivo plasmablast enrichment technique to isolate a human monoclonal antibody, 46B8 that neutralizes all IBVs tested in vitro and protects mice against letha
Autor:
Alberto Estevez, Patrick J. Lupardus, Gerald R. Nakamura, Henry Chiu, Jeremy Stinson, Lynn Kamen, Lee R. Swem, Nan Chiang, Ning Chai, Summer Park, Elviza Kho, Zora Modrusan, Min Xu, Mike Reichelt, Zhonghua Lin, Elizabeth Skippington, Man-Wah Tan, Claudio Ciferri, Rina Fong
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-2 (2017)
Nature Communications
Nature Communications
Influenza B virus (IBV) causes annual influenza epidemics around the world. Here we use an in vivo plasmablast enrichment technique to isolate a human monoclonal antibody, 46B8 that neutralizes all IBVs tested in vitro and protects mice against letha