Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Laurent Renia"'
Autor:
Yun Shan Goh, Siew‐Wai Fong, Pei Xiang Hor, Chiew Yee Loh, Matthew Zirui Tay, Bei Wang, Siti Nazihah Mohd Salleh, Eve Zi Xian Ngoh, Raphael Tze Chuen Lee, Xuan Ying Poh, I. Russel Lee, Suma Rao, Po Ying Chia, Sebastian Maurer-Stroh, Cheng-I Wang, Yee‐Sin Leo, David C. Lye, Barnaby Edward Young, Lisa F.P. Ng, Laurent Renia
Publikováno v:
International Journal of Infectious Diseases, Vol 146, Iss , Pp 107147- (2024)
Objectives: The emergence of new SARS-CoV-2 variants has led to the development of Omicron-targeting bivalent mRNA vaccines. It is crucial to understand how bivalent vaccines may improve antibody responses against new variants. Methods: A total of 10
Externí odkaz:
https://doaj.org/article/10a40254e10745f0b29910119928a1bb
Autor:
Xuan Ying Poh, I. Russel Lee, Clarissa Lim, Jefanie Teo, Suma Rao, Po Ying Chia, Sean W. X. Ong, Tau Hong Lee, Ray J. H. Lin, Lisa F. P. Ng, Ee Chee Ren, Raymond T. P. Lin, Lin-Fa Wang, Laurent Renia, David Chien Lye, Barnaby E. Young
Publikováno v:
Trials, Vol 23, Iss 1, Pp 1-13 (2022)
Abstract Background Over 2021, COVID-19 vaccination programs worldwide focused on raising population immunity through the primary COVID-19 vaccine series. In Singapore, two mRNA vaccines (BNT162b2 and mRNA-1273) and the inactivated vaccine CoronaVac
Externí odkaz:
https://doaj.org/article/c98caff7101945acb1f35e219873ed4a
Autor:
Yun Shan Goh, Siew-Wai Fong, Pei Xiang Hor, Siti Naqiah Amrun, Cheryl Yi-Pin Lee, Barnaby Edward Young, Po Ying Chia, Paul A. Tambyah, Shirin Kalimuddin, Surinder Pada, Seow-Yen Tan, Louisa Jin Sun, Mark I-Cheng Chen, Yee-Sin Leo, David C. Lye, Lisa F. P. Ng, Laurent Renia
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
IntroductionCOVID-19 has a wide disease spectrum ranging from asymptomatic to severe. While humoral immune responses are critical in preventing infection, the immune mechanisms leading to severe disease, and the identification of biomarkers of diseas
Externí odkaz:
https://doaj.org/article/36243aea16a846f2b9dea4e3a465e2bd
Autor:
Yun Shan Goh, Angeline Rouers, Siew-Wai Fong, Nicole Ziyi Zhuo, Pei Xiang Hor, Chiew Yee Loh, Yuling Huang, Vanessa Kexin Neo, Isaac Kai Jie Kam, Bei Wang, Eve Zi Xian Ngoh, Siti Nazihah Mohd Salleh, Raphael Tze Chuen Lee, Surinder Pada, Louisa Jin Sun, Desmond Luan Seng Ong, Jyoti Somani, Eng Sing Lee, NCID Study Group, COVID-19 Study Group, Sebastian Maurer-Stroh, Cheng-I Wang, Yee‐Sin Leo, Ee Chee Ren, David C. Lye, Barnaby Edward Young, Lisa F. P. Ng, Laurent Renia, Jocelyn Jin Yu, Zheng Kuang Soh, Yi Qing Chin, Jonathan Jordon Lim, Juwinda Ongko, Eshele Anak Libau, Mohammed Ridzwan Bin Abdullah, Shiau Hui Diong, Jefanie Teo, He Ping Yeo
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The emergence of new SARS-CoV-2 variants, such as the more transmissible Delta and Omicron variants, has raised concerns on efficacy of the COVID-19 vaccines. Here, we examined the waning of antibody responses against different variants following pri
Externí odkaz:
https://doaj.org/article/8c044de1955f481fa270a14ebe1f274a
Autor:
Yi‐Hao Chan, Siew‐Wai Fong, Chek‐Meng Poh, Guillaume Carissimo, Nicholas Kim‐Wah Yeo, Siti Naqiah Amrun, Yun Shan Goh, Jackwee Lim, Weili Xu, Rhonda Sin‐Ling Chee, Anthony Torres‐Ruesta, Cheryl Yi‐Pin Lee, Matthew Zirui Tay, Zi Wei Chang, Wen‐Hsin Lee, Bei Wang, Seow‐Yen Tan, Shirin Kalimuddin, Barnaby Edward Young, Yee‐Sin Leo, Cheng‐I Wang, Bernett Lee, Olaf Rötzschke, David Chien Lye, Laurent Renia, Lisa F P Ng
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 6, Pp n/a-n/a (2021)
Abstract The immune responses and mechanisms limiting symptom progression in asymptomatic cases of SARS‐CoV‐2 infection remain unclear. We comprehensively characterized transcriptomic profiles, cytokine responses, neutralization capacity of antib
Externí odkaz:
https://doaj.org/article/3b73e26cedcc4068b8a198daa09cbea2
Autor:
Barnaby E Young, Wycliffe E Wei, Siew-Wai Fong, Tze-Minn Mak, Danielle E Anderson, Yi-Hao Chan, Rachael Pung, Cheryl SY Heng, Li Wei Ang, Adrian Kang Eng Zheng, Bernett Lee, Shirin Kalimuddin, Surinder Pada, Paul A Tambyah, Purnima Parthasarathy, Seow Yen Tan, Louisa Sun, Gavin JD Smith, Raymond Tzer Pin Lin, Yee-Sin Leo, Laurent Renia, Lin-Fa Wang, Lisa FP Ng, Sebastian Maurer-Stroh, David Chien Lye, Vernon J Lee
Publikováno v:
EBioMedicine, Vol 66, Iss , Pp 103319- (2021)
Background: Host determinants of severe coronavirus disease 2019 include advanced age, comorbidities and male sex. Virologic factors may also be important in determining clinical outcome and transmission rates, but limited patient-level data is avail
Externí odkaz:
https://doaj.org/article/57251a51906e4eea898c0b3503c062e7
Autor:
Cheryl Yi‐Pin Lee, Siti Naqiah Amrun, Rhonda Sin‐Ling Chee, Yun Shan Goh, Tze‐Minn Mak, Sophie Octavia, Nicholas Kim‐Wah Yeo, Zi Wei Chang, Matthew Zirui Tay, Anthony Torres‐Ruesta, Guillaume Carissimo, Chek Meng Poh, Siew‐Wai Fong, Wang Bei, Sandy Lee, Barnaby Edward Young, Seow‐Yen Tan, Yee‐Sin Leo, David C Lye, Raymond TP Lin, Sebastien Maurer‐Stroh, Bernett Lee, Cheng‐I Wang, Laurent Renia, Lisa FP Ng
Publikováno v:
Clinical & Translational Immunology, Vol 10, Iss 2, Pp n/a-n/a (2021)
Abstract Objectives The emergence of a SARS‐CoV‐2 variant with a point mutation in the spike (S) protein, D614G, has taken precedence over the original Wuhan isolate by May 2020. With an increased infection and transmission rate, it is imperative
Externí odkaz:
https://doaj.org/article/67eafde69d424090baa6fae0c95a0083
Autor:
Siti Naqiah Amrun, Cheryl Yi-Pin Lee, Bernett Lee, Siew-Wai Fong, Barnaby Edward Young, Rhonda Sin-Ling Chee, Nicholas Kim-Wah Yeo, Anthony Torres-Ruesta, Guillaume Carissimo, Chek Meng Poh, Zi Wei Chang, Matthew Zirui Tay, Yi-Hao Chan, Mark I-Cheng Chen, Jenny Guek-Hong Low, Paul A. Tambyah, Shirin Kalimuddin, Surinder Pada, Seow-Yen Tan, Louisa Jin Sun, Yee-Sin Leo, David C. Lye, Laurent Renia, Lisa F.P. Ng
Publikováno v:
EBioMedicine, Vol 58, Iss , Pp 102911- (2020)
Background: Given the unceasing worldwide surge in COVID-19 cases, there is an imperative need to develop highly specific and sensitive serology assays to define exposure to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Methods: Poole
Externí odkaz:
https://doaj.org/article/3fef66fffc014648a71bf06e74b83944
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Since December 2019, the novel coronavirus, SARS-CoV-2, has garnered global attention due to its rapid transmission, which has infected more than two million people worldwide. Early detection of SARS-CoV-2 is one of the crucial interventions to contr
Externí odkaz:
https://doaj.org/article/f58c84713b8a4308a51c4a992ea39091
Autor:
Sean Wei Xiang Ong, Wilnard Yeong Tze Tan, Yi‐Hao Chan, Siew‐Wai Fong, Laurent Renia, Lisa FP Ng, Yee‐Sin Leo, David Chien Lye, Barnaby Edward Young
Publikováno v:
Clinical & Translational Immunology, Vol 9, Iss 7, Pp n/a-n/a (2020)
Abstract Objectives While the safety of non‐steroidal anti‐inflammatory drugs in COVID‐19 has been questioned, they may be beneficial given the hyper‐inflammatory immune response associated with severe disease. We aimed to assess the safety a
Externí odkaz:
https://doaj.org/article/cedb365425694b718ac292a581f03a8b