Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Alfredo Castello"'
Autor:
Natasha Johnson, Berati Cerikan, Shabaz Mohammed, Manuel Garcia-Moreno, Javier Martinez, Christopher J. Neufeldt, Alfredo Castello, Ralf Bartenschlager, Mohamed Kammoun, Jeffrey Y. Lee, Anna Andrejeva, Mirko Cortese, Marko Noerenberg, Honglin Chen, Kathryn S. Lilley, Ilan Davis, Michael L. Knight, Aino I. Järvelin, Ni Shuai, Wael Kamel, Michael J. Deery
Publikováno v:
Molecular Cell
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes COVID-19. SARS-CoV-2 relies on cellular RNA-binding proteins (RBPs) to replicate and spread, although which RBPs control its life cycle remains largely unknown. Here, we employ a mul
Autor:
Natasha Palmalux, Shabaz Mohammed, Louisa Iselin, Wael Kamel, Peter Simmonds, Alfredo Castello
Publikováno v:
trends in biochemical sciences
RNA viruses interact with a wide range of cellular RNA-binding proteins (RBPs) during their life cycle. The prevalence of these host-virus interactions has been highlighted by new methods that elucidate the composition of viral ribonucleoproteins (vR
Autor:
Wael Kamel, Maximilian Hannan, Alfredo Castello, Vincenzo Ruscica, Louisa Iselin, Samantha Moore, Manuel Garcia-Moreno, Javier Martinez, Ilan Davis, Shabaz Mohammed, Marko Noerenberg, Aino I. Järvelin, Natasha Palmalux, Andres Merits
Publikováno v:
bioRxiv
The expansion of tropical mosquito habitats and associated arboviruses is a risk for human health, and it thus becomes fundamental to identify new antiviral strategies. In this study we employ a new approach to elucidate the composition of the ribonu
Autor:
Renier A. L. van der Hoorn, Shabaz Mohammed, Gail M. Preston, Markus Kaiser, Honglin Chen, Farnusch Kaschani, Alfredo Castello, Marcel Bach-Pages, Nattapong Sanguankiattichai, Riccardo Soldan
RNA-binding proteins (RBPs) play critical roles in post-transcriptional gene regulation and are known to contribute to plant immunity. To understand the responses of cellular RBPs to an immune elicitor, we applied RNA interactome capture to Arabidops
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c69409250951f8ae176d721e9f8c2677
https://doi.org/10.1101/2020.09.16.299701
https://doi.org/10.1101/2020.09.16.299701
Publikováno v:
Seminars in Cell & Developmental Biology
Highlights • Proteomic studies have uncovered more than a thousand cellular proteins that are present in the particles of RNA viruses. • Strikingly, nearly four hundred of these are RNA-binding proteins (RBPs). • Several virion-incorporated RBP
Discovering the RNA-Binding Proteome of Plant Leaves with an Improved RNA Interactome Capture Method
Autor:
Felix Homma, Shabaz Mohammed, Markus Kaiser, Marcel Bach-Pages, Renier A. L. van der Hoorn, Alfredo Castello, Farnusch Kaschani, Gail M. Preston, Jiorgos Kourelis
Publikováno v:
Biomolecules
Biomolecules, Vol 10, Iss 661, p 661 (2020)
Volume 10
Issue 4
Biomolecules, Vol 10, Iss 661, p 661 (2020)
Volume 10
Issue 4
RNA-binding proteins (RBPs) play a crucial role in regulating RNA function and fate. However, the full complement of RBPs has only recently begun to be uncovered through proteome-wide approaches such as RNA interactome capture (RIC). RIC has been app
Autor:
Caroline E. Lenz, Matthias W. Hentze, Joel I. Perez-Perri, Marko Noerenberg, Shabaz Mohammed, Alfredo Castello, Wael Kamel
Publikováno v:
Nat Protoc
Interactions between RNA-binding proteins (RBPs) and RNAs are critical to cell biology. However, methods to comprehensively and quantitatively assess these interactions within cells were lacking. RNA interactome capture (RIC) uses in vivo UV crosslin
Autor:
Alfredo Castello, Matthias W. Hentze, Jeroen Krijgsveld, Bernd Fischer, Mandy Rettel, Birgit Rogell
Publikováno v:
RNA. 23:1290-1302
RNA-binding proteins (RBPs) play essential roles in RNA biology, responding to cellular and environmental stimuli to regulate gene expression. Important advances have helped to determine the (near) complete repertoires of cellular RBPs. However, iden
Autor:
Gian Gaetano Tartaglia, Daniela Sarnataro, Ilenia Agliarulo, Shabaz Mohammed, Matteo Landriscina, Aino I. Järvelin, Franca Esposito, Pietro Zoppoli, Valentina Condelli, Giovanni Calice, Alfredo Castello, Elias Bechara, Danilo Swann Matassa, Rosario Avolio
Publikováno v:
Nucleic Acids Research
Syndesmos (SDOS) is a functionally poorly characterized protein that directly interacts with p53 binding protein 1 (53BP1) and regulates its recruitment to chromatin. We show here that SDOS interacts with another important cancer-linked protein, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::387103577b0c8e6c53e3cc7b1007bc2c
https://doi.org/10.1093/nar/gky873
https://doi.org/10.1093/nar/gky873
Publikováno v:
Trends in Endocrinology and Metabolism
In the past century, few areas of biology advanced as much as our understanding of the pathways of intermediary metabolism. Initially considered unimportant in terms of gene regulation, crucial cellular fate changes, cell differentiation, or malignan