Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jorge Cruz-Reyes"'
Publikováno v:
RNA. 12:1292-1303
RBP16 is an abundant RNA binding protein from Trypanosoma brucei mitochondria that affects both RNA editing and stability. We report here experiments aimed at elucidating the mechanism of RBP16 function in RNA editing. In in vitro RNA editing assays,
Autor:
Jorge, Cruz-Reyes
Publikováno v:
Methods in enzymology. 424
Multisubunit RNA editing complexes recognize thousands of pre-mRNA sites in the single mitochondrion of trypanosomes. Specific determinants at each editing site must trigger the complexes to catalyze a complete cycle of either uridylate insertion or
Autor:
Alfredo J. Hernandez, Paula Pavia, Daniel Osterwisch, Jorge Cruz-Reyes, Catherine Cifuentes-Rojas, Concepción J. Puerta
Publikováno v:
The Journal of biological chemistry. 282(7)
Multisubunit RNA editing complexes catalyze uridylate insertion/deletion RNA editing directed by complementary guide RNAs (gRNAs). Editing in trypanosome mitochondria is transcript-specific and developmentally controlled, but the molecular mechanisms
Publikováno v:
International journal for parasitology. 36(12)
Mitochondrial gene expression in kinetoplastids is controlled after transcription, potentially at the levels of RNA maturation, stability and translation. Among these processes, RNA editing by U-insertion/deletion catalysed by multi-subunit editing c
Autor:
Kari Halbig, Anastasia Sacharidou, Mónica De Nova-Ocampo, Catherine Cifuentes-Rojas, Jorge Cruz-Reyes
Publikováno v:
Nucleic Acids Research
Trypanosome RNA editing by uridylate insertion or deletion cycles is a mitochondrial mRNA maturation process catalyzed by multisubunit complexes. A full-round of editing entails three consecutive steps directed by partially complementary guide RNAs:
Publikováno v:
Molecular cell. 1(3)
In the currently envisioned mechanism of trypanosome mitochondrial RNA editing, U-insertion and U-deletion cycles begin with a common kind of gRNA-directed cleavage. However, natural, altered, and mutationally interconverted editing sites reveal that
Publikováno v:
Biochemistry. 37(17)
It has been widely believed that the electrophoretic migration difference of otherwise identical RNAs with a P versus OH terminus would be the same as occurs for DNA, a fairly reproducible approximately 1/2 nucleotide (nt) offset. RNA with a 5'-OH in
Publikováno v:
Scopus-Elsevier
RNA editing in kinetoplastids, the specific insertion and deletion of U residues, requires endonuclease cleavage of the pre-mRNA at each cycle of insertion/deletion. We have resolved three endoribonuclease activities from Trypanosoma brucei mitochond
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::0a3a80a75baea5c80e164c594bbf74c7
https://europepmc.org/articles/PMC1369480/
https://europepmc.org/articles/PMC1369480/