Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Elad Ziv"'
Autor:
Angelica Macauda, Alyssa Clay-Gilmour, Thomas Hielscher, Michelle A.T. Hildebrandt, Marcin Kruszewski, Robert Z. Orlowski, Shaji K. Kumar, Elad Ziv, Enrico Orciuolo, Elizabeth E. Brown, Asta Försti, Rosalie G. Waller, Mitchell J. Machiela, Stephen J. Chanock, Nicola J. Camp, Marcin Rymko, Małgorzata Raźny, Wendy Cozen, Judit Várkonyi, Chiara Piredda, Matteo Pelosini, Alem A. Belachew, Edyta Subocz, Kari Hemminki, Malwina Rybicka-Ramos, Graham G. Giles, Roger L. Milne, Jonathan N. Hofmann, Jan Maciej Zaucha, Annette Juul Vangsted, Hartmut Goldschmidt, S. Vincent Rajkumar, Waldemar Tomczak, Juan Sainz, Aleksandra Butrym, Marzena Watek, Elżbieta Iskierka-Jazdzewska, Gabriele Buda, Dennis P. Robinson, Artur Jurczyszyn, Marek Dudziński, Joaquin Martinez-Lopez, Jason P. Sinnwell, Susan L. Slager, Krzysztof Jamroziak, Rui Manuel Vieira Reis, Niels Weinhold, Parveen Bhatti, Luis G. Carvajal-Carmona, Daria Zawirska, Aaron D. Norman, Grzegorz Mazur, Sonja I. Berndt, Daniele Campa, Celine M. Vachon, Federico Canzian
Publikováno v:
Cancer Epidemiology, Biomarkers & Prevention. 31:1863-1866
Background: Genome-wide association studies (GWAS) of multiple myeloma in populations of European ancestry (EA) identified and confirmed 24 susceptibility loci. For other cancers (e.g., colorectum and melanoma), risk loci have also been associated wi
Autor:
Mattias Johansson, Rebecca E. Graff, Karl Smith-Byrne, John S. Witte, Linda Kachuri, Sara R. Rashkin, Elad Ziv, Travis J. Meyers
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Nature communications, vol 11, iss 1
Nature Communications
Nature communications, vol 11, iss 1
Nature Communications
Cancer risk is determined by a complex interplay of environmental and heritable factors. Polygenic risk scores (PRS) provide a personalized genetic susceptibility profile that may be leveraged for disease prediction. Using data from the UK Biobank (4
Autor:
Rocío Rodríguez-Valentín, Gabriela Torres-Mejía, Louis Martínez-Matsushita, Angélica Angeles-Llerenas, Liliana Gómez-Flores-Ramos, Roger K. Wolff, Kathy B. Baumgartner, Lisa M. Hines, Elad Ziv, Lourdes Flores-Luna, Luisa Ma. Sánchez-Zamorano, Eduardo Ortiz-Panozo, Martha L. Slattery
Publikováno v:
Scientific Reports
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Breast cancer is a multifactorial disease in which the interplay among multiple risk factors remains unclear. Energy homeostasis genes play an important role in carcinogenesis and their interactions with the serum concentrations of IGF-1 and IGFBP-3
Autor:
Ana P. Estrada-Florez, Luis G. Carvajal-Carmona, Juan Carlos Martínez-Chéquer, Tatianna Vidaurre, Susan L. Neuhausen, Guadalupe Polanco-Echeverry, Gabriela Torres-Mejía, Magdalena Echeverry, Javier Torres, Jeffrey N. Weitzel, Laura Fejerman, Sandro Casavilca Zambrano, S Sawyer, Yiwey Shieh, Paul C. Lott, Christopher A. Haiman, Scott Huntsman, Elad Ziv, Donglei Hu, Esther M. John, Mabel Bohorquez, Katie Marker, Lawrence H. Kushi
Publikováno v:
JNCI Journal of the National Cancer Institute
J Natl Cancer Inst
J Natl Cancer Inst
Background More than 180 single nucleotide polymorphisms (SNPs) associated with breast cancer susceptibility have been identified; these SNPs can be combined into polygenic risk scores (PRS) to predict breast cancer risk. Because most SNPs were ident
Autor:
Maruta A. Blatchins, Stephen K. Van Den Eeden, Caroline G. Tai, Lawrence H. Kushi, John S. Witte, Lancelote Leong, Taylor B. Cavazos, Travis J. Meyers, Rebecca E. Graff, Douglas A. Corley, Stacey E. Alexeeff, Linda Kachuri, Khanh K. Thai, Thomas J. Hoffmann, Eric Jorgenson, Joshua D. Hoffman, Elad Ziv, Lori C. Sakoda, Sara R. Rashkin, Laurel A. Habel, Nima C. Emami
Publikováno v:
Nature communications, vol 12, iss 1
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Nature Communications
Even distinct cancer types share biological hallmarks. Here, we investigate polygenic risk score (PRS)-specific pleiotropy across 16 cancers in European ancestry individuals from the Genetic Epidemiology Research on Adult Health and Aging cohort (16,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a15285feb7cdbfef25a8a53413e0b989
https://escholarship.org/uc/item/2x39f6df
https://escholarship.org/uc/item/2x39f6df
Autor:
Travis J. Meyers, Douglas A. Corley, Sara R. Rashkin, Maruta A. Blatchins, Lawrence H. Kushi, Eric Jorgenson, Taylor B. Cavazos, Stacey E. Alexeeff, Rebecca E. Graff, John S. Witte, Khanh K. Thai, Thomas J. Hoffmann, Linda Kachuri, Lori C. Sakoda, Joshua D. Hoffman, Elad Ziv, Stephen K. Van Den Eeden, Laurel A. Habel, Nima C. Emami
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature communications, vol 11, iss 1
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature communications, vol 11, iss 1
Deciphering the shared genetic basis of distinct cancers has the potential to elucidate carcinogenic mechanisms and inform broadly applicable risk assessment efforts. Here, we undertake genome-wide association studies (GWAS) and comprehensive evaluat
Autor:
Jeffrey A. Tice, Scott Huntsman, Elad Ziv, Lin Ma, Donglei Hu, Charlotte C. Gard, Jessica W.T. Leung, Steven R. Cummings, Yiwey Shieh, Karla Kerlikowske
Publikováno v:
Breast Cancer Research and Treatment. 166:603-612
Models that predict the risk of estrogen receptor (ER)-positive breast cancers may improve our ability to target chemoprevention. We investigated the contributions of sex hormones to the discrimination of the Breast Cancer Surveillance Consortium (BC
Autor:
Dejana Braithwaite, Amy Trentham-Dietz, Louise C. Walter, Diana S. M. Buist, Diana L. Miglioretti, Brian L. Sprague, Weiwei Zhu, Tracy Onega, Jeffrey A. Tice, Karla Kerlikowske, Louise M. Henderson, Elad Ziv, Joshua Demb
Importance First-degree family history is a strong risk factor for breast cancer, but controversy exists about the magnitude of the association among older women. Objective To determine whether first-degree family history is associated with increased
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44f495a058a8335f011223947ee629a7
https://europepmc.org/articles/PMC5876845/
https://europepmc.org/articles/PMC5876845/
Autor:
Noah Zaitlen, John S. Witte, Lancelote Leong, Michael N. Passarelli, Caroline G. Tai, Scott Huntsman, Joshua D. Hoffman, Nima C. Emami, Elad Ziv, Donglei Hu, Rebecca E. Graff, Arunabha Majumdar, Dexter Hadley
Publikováno v:
PLoS Genetics, Vol 13, Iss 3, p e1006690 (2017)
PLoS genetics, vol 13, iss 3
PLoS Genetics
PLoS genetics, vol 13, iss 3
PLoS Genetics
Breast cancer is the most common solid organ malignancy and the most frequent cause of cancer death among women worldwide. Previous research has yielded insights into its genetic etiology, but there remains a gap in the understanding of genetic facto
Autor:
Esther M. John, Laura Fejerman, Mariana C. Stern, Eliseo J. Pérez-Stable, Elad Ziv, Christopher A. Haiman, Scott Huntsman, Donglei Hu
Publikováno v:
Cancer research, vol 73, iss 24
Multiple studies have reported that Latina women in the United States are diagnosed with breast cancer at more advanced stages and have poorer survival than non-Latina White women. However, Latinas are a heterogeneous group with individuals having di