Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Sally, John"'
Autor:
R Aspinwall, W. E. R. Ollier, Sally John, Kristian Spreckley, M Grant, C Greig, M. Doherty, Emma Gillaspy, Gillian A. Wallis
Publikováno v:
Annals of the Rheumatic Diseases. 65:1131-1138
Objective: To identify susceptibility loci for nodal osteoarthritis. Methods: A genome screen at an average marker spacing of 9.29 cM was carried out on 558 people from 202 families, of whom 491 had nodal osteoarthritis. All genotyped people were gra
Autor:
Adam S. Butterworth, Sally John, Wei V. Chen, Peter K. Gregersen, Carol J. Etzel, Jane Worthington, Christopher I. Amos, Damini Jawaheer, Alan J. Silman, Neil Shephard, Michael F. Seldin
Publikováno v:
Arthritis & Rheumatism. 54:1482-1490
Objective HLA is the most strongly associated locus in rheumatoid arthritis (RA), accounting for up to one-third of the genetic contribution. Conditioning on the effect of true disease loci such as HLA can lead to increased power to detect effects at
Autor:
Sally John, John Bowes, Kristian Spreckley, Stephen Eyre, Anne Hinks, Anne Barton, Jane Worthington
Publikováno v:
Arthritis & Rheumatism. 50:1117-1121
Objective In the era of postgenomic research, linkage- and association-based strategies are beginning to reveal novel complex disease genes. Using such an approach, a functional haplotype of the peptidylarginine deiminase 4 gene (PADI4) has recently
Publikováno v:
Arthritis & Rheumatism. 43:2771-2775
Objective. To seek potential autoimmune disease susceptibility loci by testing for linkage and linkage disequilibrium between insulin-dependent diabetes mellitus (IDDM) susceptibility loci and rheumatoid arthritis (RA). Methods. Five IDDM susceptibil
Autor:
Jane Worthington, Sheila A. Fisher, Chandrabala Shah, M S Fife, William E R Ollier, Cathryn M. Lewis, Jerry S. Lanchbury, Sally John, Gabriel S. Panayi
Publikováno v:
Arthritis & Rheumatism. 43:1673-1678
Objective Rheumatoid arthritis (RA) is the most common disabling autoimmune disease, affecting ∼1% of the population. The disease etiology is unknown, but it involves inflammation and immune dysregulation and is influenced by genetic variation at b
Autor:
W. E. R. Ollier, M. A. Gonzalez-Gay, Anne Myerscough, Sally John, Anne Barton, Jane Worthington
Publikováno v:
Scopus-Elsevier
BACKGROUND: Rheumatoid arthritis (RA) is an oligogenic disease for which only one susceptibility locus has been identified to date. Genes involved in T-cell regulation are potential candidates. Association to cytotoxic T-lymphocyte-associated-4 (CTLA
Autor:
Kai Ren Ong, Paul Brennan, Sally John, Alan J. Silman, Jane Worthington, Wendy Thomson, Bill Ollier, Ali H. Hajeer
Publikováno v:
Arthritis & Rheumatism. 40:1383-1386
Objective. To investigate linkage disequilibrium between HLA-DRB1 disease susceptibility alleles and microsatellite markers close to the prolactin gene, among women with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) and normal cont
Autor:
Sally John, Shad B. Smith, Keith Tan, Dylan W. Maixner, Gary D. Slade, Luda Diatchenko, Kirsten R. Ambrose, Dmitri V. Zaykin, William Maixner, Roger B. Fillingim, Craig L. Hyde, Richard H. Gracely
Objective Fibromyalgia (FM) represents a complex disorder that is characterized by widespread pain and tenderness and is frequently accompanied by additional somatic and cognitive/affective symptoms. Genetic risk factors are known to contribute to th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e53f272a5c2f97b1b1334d976c1307b
Autor:
Anne, Hinks, Anne, Barton, Neil, Shephard, Steve, Eyre, John, Bowes, Michele, Cargill, Eric, Wang, Xiayi, Ke, Giulia C, Kennedy, Sally, John, Jane, Worthington, Wendy, Thomson, S, Wyatt
Publikováno v:
Arthritis and Rheumatism
Objective Juvenile idiopathic arthritis (JIA) is a chronic rheumatic disease of childhood. Two well-established genetic factors known to contribute to JIA susceptibility, HLA and PTPN22, account for less than half of the genetic susceptibility to dis
Autor:
Chester V. Oddis, Hector Chinoy, F Salway, Sally John, Robert G. Cooper, Noreen Fertig, Brian D. Tait, William E R Ollier
Objective: To determine whether interferon-gamma (IFN-γ) and interleukin-4 (IL-4) genes confer susceptibility for the idiopathic inflammatory myopathies (IIMs). Methods: A large cross-sectional study of UK caucasian adults with polymyositis (PM, n =
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec4b07ba8a7f15665200a8dde417c080
https://europepmc.org/articles/PMC1955105/
https://europepmc.org/articles/PMC1955105/