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pro vyhledávání: '"Mckie, Lisa"'
Autor:
Megaw R; MRC Human Genetics Unit, MRC Institute of Genetics & Cancer, University of Edinburgh, Western General Hospital, Edinburgh, EH4 2XU, UK. roly.megaw@ed.ac.uk.; Princess Alexandra Eye Pavilion, NHS Lothian, Edinburgh, EH3 9HA, UK. roly.megaw@ed.ac.uk., Moye A; Verna and Marrs McLean Department of Biochemistry and Molecular Pharmacology, Baylor College of Medicine, Houston, TX, 77030, USA., Zhang Z; Verna and Marrs McLean Department of Biochemistry and Molecular Pharmacology, Baylor College of Medicine, Houston, TX, 77030, USA., Newton F; MRC Human Genetics Unit, MRC Institute of Genetics & Cancer, University of Edinburgh, Western General Hospital, Edinburgh, EH4 2XU, UK., McPhie F; MRC Human Genetics Unit, MRC Institute of Genetics & Cancer, University of Edinburgh, Western General Hospital, Edinburgh, EH4 2XU, UK., Murphy LC; MRC Human Genetics Unit, MRC Institute of Genetics & Cancer, University of Edinburgh, Western General Hospital, Edinburgh, EH4 2XU, UK., McKie L; MRC Human Genetics Unit, MRC Institute of Genetics & Cancer, University of Edinburgh, Western General Hospital, Edinburgh, EH4 2XU, UK., He F; Verna and Marrs McLean Department of Biochemistry and Molecular Pharmacology, Baylor College of Medicine, Houston, TX, 77030, USA., Jungnickel MK; MRC Human Genetics Unit, MRC Institute of Genetics & Cancer, University of Edinburgh, Western General Hospital, Edinburgh, EH4 2XU, UK., von Kriegsheim A; Edinburgh Cancer Research United Kingdom Centre, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, EH4 2XU, UK., Tennant PA; MRC Human Genetics Unit, MRC Institute of Genetics & Cancer, University of Edinburgh, Western General Hospital, Edinburgh, EH4 2XU, UK., Brotherton C; MRC Human Genetics Unit, MRC Institute of Genetics & Cancer, University of Edinburgh, Western General Hospital, Edinburgh, EH4 2XU, UK., Gurniak C; Institute fur Genetik, Universitat Bonn, Karlrobert-Kreiten-Strasse, 53115, Bonn, Germany., Gross AK; University of Alabama at Birmingham, 2nd Ave South, Birmingham, AL, 35294, USA., Machesky LM; CRUK Scotland Institute, Switchback Road, Bearsden, Glasgow, G61 1BD, UK.; Department of Biochemistry, University of Cambridge, Cambridge, CB1 7UY, UK., Wensel TG; Verna and Marrs McLean Department of Biochemistry and Molecular Pharmacology, Baylor College of Medicine, Houston, TX, 77030, USA., Mill P; MRC Human Genetics Unit, MRC Institute of Genetics & Cancer, University of Edinburgh, Western General Hospital, Edinburgh, EH4 2XU, UK.
Publikováno v:
Nature communications [Nat Commun] 2024 May 21; Vol. 15 (1), pp. 4316. Date of Electronic Publication: 2024 May 21.
Autor:
Findlay, Amy S., Carter, Roderick N., Starbuck, Becky, McKie, Lisa, Nováková, Klára, Budd, Peter S., Keighren, Margaret A., Marsh, Joseph A., Cross, Sally H., Simon, Michelle M., Potter, Paul K., Morton, Nicholas M., Jackson, Ian J.
Publikováno v:
Findlay, A, Carter, R N, Starbuck, B, McKie, L, Novakova, K, Budd, P S, Keighren, M, Marsh, J A, Cross, S, Simon, M, Potter, P, Morton, N M & Jackson, I J 2018, ' Mouse Idh3a Mutations Cause Retinal Degeneration and Reduced Mitochondrial Function ', Disease Models and Mechanisms . https://doi.org/10.1242/dmm.036426
Disease Models & Mechanisms
Disease Models & Mechanisms, Vol 11, Iss 12 (2018)
Disease Models & Mechanisms
Disease Models & Mechanisms, Vol 11, Iss 12 (2018)
Isocitrate dehydrogenase (IDH) is an enzyme required for the production of α-ketoglutarate from isocitrate. IDH3 generates the NADH used in the mitochondria for ATP production, and is a tetramer made up of two α, one β and one γ subunit. Loss-of-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::faece8faf16829b72ec7503c40489710
https://www.pure.ed.ac.uk/ws/files/77515994/dmm.036426.full.pdf
https://www.pure.ed.ac.uk/ws/files/77515994/dmm.036426.full.pdf