Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Frank Schuettauf"'
Autor:
Dominika Nowakowska, Teresio Avitabile, Tomasz Kocki, Michal Fiedorowicz, Agnieszka Kaminska, Paweł Grieb, Frank Schuettauf, Michele Reibaldi, Tomasz Choragiewicz, Robert Rejdak, Kamila Wojtunik, Eberhart Zrenner, Mario Damiano Toro, Sebastian Thaler, Waldemar A. Turski
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Frontiers in Physiology
Frontiers in Physiology
Kynurenines, products of tryptophan (TRP) metabolism, display neurotoxic (e.g., 3-hydroxykynurenine; 3-HK), or neuroprotective (e.g., kynurenic acid; KYNA) properties. Imbalance between the enzymes constituting the kynurenine pathway (KP) plays a rol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1476c63e578cd41ca650a2af585036ed
http://hdl.handle.net/11588/894806
http://hdl.handle.net/11588/894806
Autor:
Maciej Gasior, Tomasz Zarnowski, Robert Rejdak, Iwona Zarnowska, Tomasz Choragiewicz, Sebastian Thaler, Frank Schuettauf, Eberhart Zrenner
Publikováno v:
Ophthalmic Research. 53:162-167
Objective: This study was conducted to investigate neuroprotective effects of a high fat/low carbohydrate and protein diet (ketogenic diet, KD) in a model of N-methyl D-aspartate (NMDA)-induced retinal ganglion cell (RGC) damage in juvenile and young
Autor:
Anselm Jünemann, Paweł Grieb, Tomasz Chorągiewicz, Sebastian Thaler, Eberhart Zrenner, Tomasz Żarnowski, Robert Rejdak, Frank Schuettauf, Waldemar A. Turski
Publikováno v:
Pharmacological Reports. 63:1324-1334
The kynurenine aminotransferases (KATs) KAT I and KAT II are pivotal to the synthesis of kynurenic acid (KYNA), the only known endogenous glutamate receptor antagonist and neuroprotectant. KAT I and II have been found in avian, rodent, and human reti
Autor:
Paweł Grieb, Michal Fiedorowicz, Dorota Sulejczak, Robert Rejdak, Tomasz Zarnowski, Sebastian Thaler, Tomasz Choragiewicz, Eberhart Zrenner, Piotr Stopa, Frank Schuettauf
Publikováno v:
Medical University of Lublin
Iron overload can contribute to oxidative stress in many tissues. We studied the effects of pretreatment with iron dextran on RGC loss in a calibrated partial optic nerve crush (PONC) model in rats, along with the protection offered by tempol (4-hydr
Autor:
Sigrid Henke-Fahle, Sylvia Bolz, Michal Fiedorowicz, Eberhart Zrenner, Focke Ziemssen, Sebastian Thaler, Ayseguel Tura, Frank Schuettauf, Tomasz Choragiewicz, Efdal Yoeruek, Karl Ulrich Bartz-Schmidt
Publikováno v:
Acta Ophthalmologica. 88:e170-e176
Purpose: To evaluate the effects of intravitreally introduced vascular endothelial growth factor (VEGF) inhibitors in rat eyes with healthy retinal ganglion cells (RGC) and into others with N-methyl-D-aspartate (NMDA)-induced RGC damage. Methods: Bev
Autor:
Lukas Rüttiger, Hans F. Wehrl, Thomas Peters, Marlies Knipper, Bernd Wissinger, Susanne C. Beck, Frank Schuettauf, Felix Tonagel, Simone Schimpf, Juergen Laufs, Marcel V. Alavi, Ulrich Schraermeyer, Bernd J. Pichler, Stefanie Bette
Publikováno v:
Brain. 130:1029-1042
Autosomal dominant optic atrophy (adOA) is a juvenile onset, progressive ocular disorder characterized by bilateral loss of vision, central visual field defects, colour vision disturbances, and optic disc pallor. adOA is most frequently associated wi
Autor:
Eberhart Zrenner, Zbigniew Zagórski, Robert Rejdak, Paweł Grieb, Cristiana Lehaci, Sylvia Bolz, Sebastian Thaler, Anna Mańkowska, Anselm Jünemann, Tomasz Zarnowski, Frank Schuettauf
Publikováno v:
Experimental Eye Research. 83:1128-1134
Citicoline and lithium (Li−) have been shown to support retinal ganglion cell (RGC) survival and axon regeneration in vitro. Optic nerve crush (ONC) is a model of both brain axonal injury and certain aspects of the glaucomatous degeneration of RGC.
Autor:
Michal Fiedorowicz, Paweł Grieb, Sebastian Thaler, Robert Rejdak, Michal Wozniak, Frank Schuettauf
Publikováno v:
Folia neuropathologica. 52(3)
Background: The efficacy of tempol and its acyl derivative tempol-C8 as retinoprotective agents was compared in a rat model of NMDA-induced retinal ganglion cell (RGC) damage. Material and methods: Tempol or tempol-C8 in different doses was administe
Autor:
Rong Wen, Kristine Quinto, David Zurakowski, Frank Schuettauf, Alan M. Laties, Meghana A. Varde, Ralph Anderson, Dorothea Besch
Publikováno v:
Graefe's Archive for Clinical and Experimental Ophthalmology. 243:1036-1042
Premature neuronal cell death is a feature of numerous central nervous system and eye diseases, including glaucoma. Neurons (including retinal ganglion cells, RGCs) are protected by several neurotrophic factors, among those the IL-6 family of cytokin
Autor:
Anton Orlin, Frank Schuettauf, Rita Naskar, Jean Bennett, Edward M. Meyer, Nadine S. Dejneka, Christian K. Vorwerk, Kristine Quinto, Ronald Klein, David Zurakowski
Publikováno v:
Current Eye Research. 29:379-386
Purpose. Brain-derived neurotrophic factor (BDNF) and basic fibroblast growth factor (bFGF) hold much promise for the protection of retinal ganglion cells against excitotoxic cell death. We tested the possibility of delivering these growth factors to