Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Emily R. Ko"'
Autor:
Gregory D. Poore, Emily R. Ko, Ashlee Valente, Ricardo Henao, Kelsey Sumner, Christopher Hong, Thomas W. Burke, Marshall Nichols, Micah T. McClain, Erich S. Huang, Geoffrey S. Ginsburg, Christopher W. Woods, Ephraim L. Tsalik
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Background: Acute respiratory infections (ARIs) are the leading indication for antibacterial prescriptions despite a viral etiology in the majority of cases. The lack of available diagnostics to discriminate viral and bacterial etiologies contributes
Externí odkaz:
https://doaj.org/article/f135afe118c14397b5a49f351c01fca4
Autor:
Ricardo Henao, Emanuel P. Rivers, Stephen F. Kingsmore, Ephraim L. Tsalik, Raymond J. Langley, Eugenia Quackenbush, Elizabeth Petzold, Christopher W. Woods, Seth W. Glickman, Emily Lydon, Thomas W. Burke, Anja Kathrin Jaehne, Charles B. Cairns, Micah T. McClain, Vance G. Fowler, Geoffrey S. Ginsburg, Emily R Ko, Mert Aydin, Bradly P. Nicholson
Publikováno v:
EBioMedicine
EBioMedicine, Vol 48, Iss, Pp 453-461 (2019)
EBioMedicine, Vol 48, Iss, Pp 453-461 (2019)
Background: Distinguishing bacterial and viral respiratory infections is challenging. Novel diagnostics based on differential host gene expression patterns are promising but have not been translated to a clinical platform nor extensively tested. Here
Autor:
Ephraim L. Tsalik, Cassandra Fiorino, Ammara Aqeel, Yiling Liu, Ricardo Henao, Emily R. Ko, Thomas W. Burke, Megan E. Reller, Champica K. Bodinayake, Ajith Nagahawatte, Wasantha K. Arachchi, Vasantha Devasiri, Ruvini Kurukulasooriya, Micah T. McClain, Christopher W. Woods, Geoffrey S. Ginsburg, L. Gayani Tillekeratne, Klaus Schughart
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 12 (2021)
Frontiers in immunology
United States
Switzerland
Frontiers in Immunology, Vol 12 (2021)
Frontiers in immunology
United States
Switzerland
Viruses cause a wide spectrum of clinical disease, the majority being acute respiratory infections (ARI). In most cases, ARI symptoms are similar for different viruses although severity can be variable. The objective of this study was to understand t
Autor:
Melissa Ross, Ricardo Henao, Thomas W. Burke, Emily R. Ko, Micah T. McClain, Geoffrey S. Ginsburg, Christopher W. Woods, Ephraim L. Tsalik
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 12, p e0261385 (2021)
PLoS ONE, Vol 16, Iss 12, p e0261385 (2021)
Objectives Compare three host response strategies to distinguish bacterial and viral etiologies of acute respiratory illness (ARI). Methods In this observational cohort study, procalcitonin, a 3-protein panel (CRP, IP-10, TRAIL), and a host gene expr
Autor:
L. Gayani Tillekeratne, Ephraim L. Tsalik, Champica K Bodinayake, Ruvini Kurukulasooriya, Emily R Ko, Megan E. Reller, Micah T. McClain, Thomas W. Burke, Bradly P. Nicholson, Elizabeth Petzold, Christopher W. Woods, Ajith Nagahawatte, Geoffrey S. Ginsburg, Vasantha Devasiri, Ricardo Henao, Sunil Suchindran
Publikováno v:
Open Forum Infectious Diseases
Background Pathogen-based diagnostics for acute respiratory infection (ARI) have limited ability to detect etiology of illness. We previously showed that peripheral blood-based host gene expression classifiers accurately identify bacterial and viral
Autor:
Charles B. Cairns, Anja Kathrin Jaehne, Ephraim L. Tsalik, Geoffrey S. Ginsburg, Anna Mazur, Stephen F. Kingsmore, Lori L. Hudson, Raymond J. Langley, Tim Veldman, D. Freeman, Emily R Ko, Ronny M. Otero, Seth W. Glickman, Eugenia Quackenbush, Christopher W. Woods, Joseph Lucas, Vance G. Fowler, Aimee K. Zaas, Ricardo Henao, Marshall Nichols, Emanuel P. Rivers, Lawrence Carin, Micah T. McClain, Thomas W. Burke
Publikováno v:
Science Translational Medicine
Acute respiratory infections caused by bacterial or viral pathogens are among the most common reasons for seeking medical care. Despite improvements in pathogen-based diagnostics, most patients receive inappropriate antibiotics. Host response biomark