Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Janakiraman Subramanian"'
Autor:
Janakiraman Subramanian, Ossama Tawfik
Publikováno v:
Expert Review of Anticancer Therapy. 21:877-886
Introduction: Non-small cell lung cancer (NSCLC), which accounts for the majority of lung cancer diagnoses in the United States, has many known driver mutations, including MET exon 14 skipping muta...
Autor:
Nabil Chehab, Melissa Pavilack, Janakiraman Subramanian, Jennifer W. Wu, Mei Sheng Duh, François Laliberté, Anne C. Chiang, Ancilla W. Fernandes
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-13 (2020)
BMC Cancer
BMC Cancer
Background The objective of this study was to investigate real-world EGFR mutation testing in patients with metastatic non-small cell lung cancer (NSCLC) upon progression on first−/second-generation epidermal growth factor receptor (EGFR)-tyrosine
Autor:
Janakiraman Subramanian, Lara Kujtan
Publikováno v:
Expert Review of Anticancer Therapy. 19:547-559
Introduction: Epidermal growth factor receptor (EGFR) mutations are well-described drivers of non-small cell lung cancer (NSCLC) and EGFR tyrosine kinase inhibitors (TKIs) have become key components of the NSCLC front-line treatment landscape. Tumors
Publikováno v:
Seminars in Oncology. 46:271-283
The development of first-, second-, and third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) has revolutionized the treatment of patients with non-small cell lung cancer (NSCLC) harboring mutations in the EGFR. H
Publikováno v:
Lung cancer (Amsterdam, Netherlands). 154
There are limited data on the role for chemotherapy in patients80 years old with advanced stage non-small cell lung carcinoma (NSCLC). We used the National Cancer Database (NCDB) to evaluate treatment patterns and outcomes for patients ≥80 years ol
Publikováno v:
EJC Supplements
Tobacco smoking is the most common cause of lung cancer, but approximately 10-25% of patients with lung cancer are life-long never smokers. The cause of lung cancer in never smokers is unknown, although tobacco-smoke exposure may play a role in some
Autor:
Jason Walker, Mark A. Watson, Richard K. Wilson, Dong Hai Xiong, Ron Bose, Robert S. Fulton, Li Ding, Christopher G. Maher, Ramaswamy Govindan, Malachi Griffith, Ken Chen, Lucinda Fulton, David M. Ornitz, Janakiraman Subramanian, Ming You, Elaine R. Mardis, Nathan D. Dees, David J. Dooling, Krishna L. Kanchi, Sandra McDonald, John W. Wallis
Publikováno v:
Cell. 150:1121-1134
SummaryWe report the results of whole-genome and transcriptome sequencing of tumor and adjacent normal tissue samples from 17 patients with non-small cell lung carcinoma (NSCLC). We identified 3,726 point mutations and more than 90 indels in the codi
Vascular Endothelial Growth Factor Receptor Tyrosine Kinase Inhibitors in Non–Small-Cell Lung Cancer
Publikováno v:
Clinical Lung Cancer. 11:311-319
Angiogenesis is essential for cancer growth and progression. Vascular endothelial growth factor (VEGF) plays a crucial role in angiogenesis. The addition of bevacizumab, an antibody to vascular endothelial growth factor (VEGF), to paclitaxel and carb
Autor:
Janakiraman Subramanian, Trent West, Brandon Weckbaugh, Timothy J. Pluard, John A. Spertus, Melissa Rosado-de-Christenson
Publikováno v:
Journal of Clinical Oncology. 36:1558-1558
1558Background: Screening high risk patients for lung cancer with Low Dose Computed Tomography (LDCT) reduces lung cancer-specific mortality, however its adoption in routine clinical care has been ...
Publikováno v:
Journal of Thoracic Oncology. 2:827-830
Background Tobacco smoking leads to lung cancer. Approximately 10% of patients with lung cancer are life long never-smokers. There are only limited data available on the clinical characteristics and outcomes of lung cancer in never-smokers from the W