Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Wain, Louise V"'
Autor:
Nakanishi, Tomoko, Cerani, Agustin, Forgetta, Vincenzo, Zhou, Sirui, Allen, Richard J, Leavy, Olivia C, Koido, Masaru, Assayag, Deborah, Jenkins, R Gisli, Wain, Louise V, Yang, Ivana V, Lathrop, G Mark, Wolters, Paul J, Schwartz, David A, Richards, J Brent
Publikováno v:
The European respiratory journal, vol 59, iss 2
BackgroundIdiopathic pulmonary fibrosis (IPF) is a progressive, fatal fibrotic interstitial lung disease. Few circulating biomarkers have been identified to have causal effects on IPF.MethodsTo identify candidate IPF-influencing circulating proteins,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::2001c3ec3a05f3b7b57f88e98f79ade2
https://escholarship.org/uc/item/8tr5h2nk
https://escholarship.org/uc/item/8tr5h2nk
Autor:
Wild, Jim M., Porter, Joanna C., Molyneaux, Philip L., George, Peter M., Stewart, Iain, Allen, Richard James, Aul, Raminder, Baillie, John Kenneth, Barratt, Shaney L., Beirne, Paul, Bianchi, Stephen M., Blaikley, John F., Brooke, Jonathan, Chaudhuri, Nazia, Collier, Guilhem, Denneny, Emma K., Docherty, Annemarie, Fabbri, Laura, Gibbons, Michael A., Gleeson, Fergus V., Gooptu, Bibek, Hall, Ian P., Hanley, Neil A., Heightman, Melissa, Hillman, Toby E., Johnson, Simon R., Jones, Mark G., Khan, Fasihul, Lawson, Rod, Mehta, Puja, Mitchell, Jane A., Poinasamy, Krisnah, Quint, Jennifer K., Rivera-Ortega, Pilar, Semple, Malcolm, Simpson, A. John, Smith, D.J.F., Spears, Mark, Spencer, LIsa G., Stanel, Stefan C., Thickett, David R., Thompson, A.A. Roger, Walsh, Simon L.F., Weatherley, Nicholas D., Weeks, Mark Everard, Wootton, Dan G., Brightling, Chris E., Chambers, Rachel C., Ho, Ling-Pei, Jacob, Joseph, Piper Hanley, Karen, Wain, Louise V., Jenkins, R. Gisli
Introduction The COVID-19 pandemic has led to over 100 million cases worldwide. The UK has had over 4 million cases, 400 000 hospital admissions and 100 000 deaths. Many patients with COVID-19 suffer long-term symptoms, predominantly breathlessness a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::3902aa85f0b2028228d6a6a1d2952ea2
Autor:
Allen, Richard J., Porte, Joanne, Braybrooke, Rebecca, Flores, Carlos, Fingerlin, Tasha E., Oldham, Justin M., Guillen-Guio, Beatriz, Ma, Shwu-Fan, Okamoto, Tsukasa, John, Alison E., Obeidat, Ma'en, Yang, Ivana V., Henry, Amanda, Hubbard, Richard B., Navaratnam, Vidya, Saini, Gauri, Thompson, Norma, Booth, Helen L., Hart, Simon P., Hill, Mike R., Hirani, Nik, Maher, Toby M., McAnulty, Robin J., Millar, Ann B., Molyneaux, Philip L., Parfrey, Helen, Rassl, Doris M., Whyte, Moira K.B., Fahy, William A., Marshall, Richard P., Oballa, Eunice, Nickle, David C., Sin, Don D., Timens, Wim, Shrine, Nick, Sayers, Ian, Hall, Ian P., Noth, Imre, Schwartz, David A., Tobin, Martin D., Wain, Louise V., Jenkins, R. Gisli
BackgroundIdiopathic pulmonary fibrosis (IPF) is a chronic progressive lung disease with high mortality, uncertain cause, and few treatment options. Studies have identified a significant genetic risk associated with the development of IPF; however, m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::16e7c9b2bd556397cb25e782e141063e
Autor:
John, Catherine, Hui, Jennie, Nielsen, Sune Fallgaard, Rafaels, Nicholas, Hansel, Nadia N., Shrine, Nick, Kilty, Iain, Malarstig, Anders, Jelinsky, Scott A, Vedel-Krogh, Signe, Barnes, Kathleen, Hall, Ian P., Beilby, John, Musk, Arthur W., James, Alan, Wain, Louise V., Tobin, Martin D.
Background: Genome-wide association studies have identified numerous genetic regions that influence cross-sectional lung function. Longitudinal decline in lung function also includes a heritable component but the genetic determinants have yet to be d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::85cf7b134822ae616225ec89c2dd76c3
https://nottingham-repository.worktribe.com/file/858725/1/400.full.pdf
https://nottingham-repository.worktribe.com/file/858725/1/400.full.pdf
Autor:
Aschard, Hugues, Tobin, Martin D, Hancock, Dana B., Skurnik, David, Sood, Akshay, James, Alan, Smith, Albert Vernon, Manichaikul, Ani, Campbell, Archie, Prins, Bram P, Hayward, Caroline, Loth, Daan W., Porteous, David, Strachan, David P, Zeggini, Eleftheria, O'Connor, George T., Brusselle, Guy G., Boezen, H. Marike, Schulz, Holger, Deary, Ian J, Hall, Ian P, Rudan, Igor, Kaprio, Jaakko, Wilson, James, Wilk, Jemma B., Huffman, Jennifer, Zhao, Jing Hua, de Jong, Kim, Lyytikäinen, Leo-Pekka, Wain, Louise V, Jarvelin, Marjo-Riitta, Kahonen, Mika, Fornage, Myriam, Polasek, Ozren, Cassano, Patricia A., Barr, R. Graham, Rawal, Rajesh, Harris, Sarah, Gharib, Sina A., Enroth, Stefan, Heckbert, Susan R., Lehtimaki, Terho, Gyllensten, Ulf, Jackson, Victoria E, Gudnason, Vilmundur, Tang, Wenbo, Dupuis, Josee, Artigas, María Soler, Joshi, Amit D, Kraft, Peter
Publikováno v:
Aschard, H, Tobin, M D, Hancock, D B, Skurnik, D, Sood, A, James, A, Smith, A V, Manichaikul, A, Campbell, A, Prins, B P, Hayward, C, Loth, D W, Porteous, D, Strachan, D P, Zeggini, E, O'Connor, G T, Brusselle, G G, Boezen, H M, Schulz, H, Deary, I J, Hall, I P, Rudan, I, Kaprio, J, Wilson, J, Wilk, J B, Huffman, J, Zhao, J H, de Jong, K, Lyytikäinen, L-P, Wain, L V, Jarvelin, M-R, Kahonen, M, Fornage, M, Polasek, O, Cassano, P A, Barr, R G, Rawal, R, Harris, S, Gharib, S A, Enroth, S, Heckbert, S R, Lehtimaki, T, Gyllensten, U, Jackson, V E, Gudnason, V, Tang, W, Dupuis, J, Artigas, M S, Joshi, A D & Kraft, P 2017, ' Evidence for large-scale gene-by-smoking interaction effects on pulmonary function ', International Journal of Epidemiology . https://doi.org/10.1093/ije/dyw318
Background: Smoking is the strongest environmental risk factor for reduced pulmonary function. The genetic component of various pulmonary traits has also been demonstrated, and at least 26 loci have been reproducibly associated with either FEV1 (forc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3094::70b653977e1e458d63b94c2256084e3b
https://www.pure.ed.ac.uk/ws/files/30257660/Int._J._Epidemiol._2017_Aschard_ije_dyw318.pdf
https://www.pure.ed.ac.uk/ws/files/30257660/Int._J._Epidemiol._2017_Aschard_ije_dyw318.pdf
Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation
Autor:
Wain, Louise V., Miller, Suzanne, Kheirallah, Abdul Kader, Huffman, Jennifer E., Ntalla, Ioanna, Shrine, Nick, Trochet, Holly, McArdle, Wendy L., Alves, Alexessander Couto, Hui, Jennie, Zhao, Jing Hua, Joshi, Peter K., Teumer, Alexander, Albrecht, Eva, Imboden, Medea, Rawal, Rajesh, Lopez, Lorna M., Marten, Jonathan, Enroth, Stefan, Surakka, Ida, Polasek, Ozren, Granell, Raquel, Hysi, Pirro G., Flexeder, Claudia, Mahajan, Anubha, Beilby, John, Brandsma, Corry-Anke, Campbell, Harry, Gieger, Christian, Grallert, Harald, Hammond, Chris J., Harris, Sarah E., Hartikainen, Anna-Liisa, Henderson, John, Hocking, Lynne, Horikoshi, Momoko, Ingelsson, Erik, Kemp, John P., Kolcic, Ivana, Kumar, Ashish, Lind, Lars, Musk, Arthur W., Navarro, Pau, Nickle, David C., Padmanabhan, Sandosh, Raitakari, Olli T., Ried, Janina S., Ripatti, Samuli, Schulz, Holger, Scott, Robert A., Sin, Don D., Starr, John M., Deloukas, Panos, Hansell, Anna L., Hubbard, Richard, Jackson, Victoria E., Marchini, Jonathan, Pavord, Ian, Thomson, Neil C., Zeggini, Eleftheria, Wild, Sarah H., Wright, Alan F., Zemunik, Tatijana, Jarvis, Deborah L., Spector, Tim D., Evans, David M., Vitart, Veronique, Gyllensten, Ulf, Rudan, Igor, Deary, Ian J., Karrasch, Stefan, Probst-Hensch, Nicole M., Heinrich, Joachim, Stubbe, Beate, Wilson, James F., Wareham, Nicholas J., James, Alan L., Morris, Andrew P., Jarvelin, Marjo-Riitta, Hayward, Caroline, Sayers, Ian, Strachan, David P., Hall, Ian P., Tobin, Martin D.
Lung function measures are used in the diagnosis of chronic obstructive pulmonary disease. In 38,199 European ancestry individuals, we studied genome-wide association of forced expiratory volume in 1 s (FEV1), forced vital capacity (FVC) and FEV1/FVC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::d014b29410aa09f3f438dd0b01b5abd2
Autor:
Wain, Louise V., Shrine, Nick, Miller, Suzanne, Jackson, Victoria E., Ntalla, Ioanna, Artigas, Maria Soler, Billington, Charlotte K., Kheirallah, Abdul Kader, Allen, Richard, Cook, James P., Probert, Kelly, Obeidat, Ma'en, Bosse, Yohan, Hao, Ke, Postma, Dirkje S., Pare, Peter D., Ramasamy, Adaikalavan, Maegi, Reedik, Mihailov, Evelin, Reinmaa, Eva, Melen, Erik, O'Connell, Jared, Frangou, Eleni, Delaneau, Olivier, Freeman, Colin, Petkova, Desislava, McCarthy, Mark, Sayers, Ian, Deloukas, Panos, Hubbard, Richard, Pavord, Ian, Hansell, Anna L., Thomson, Neil C., Zeggini, Eleftheria, Morris, Andrew P., Marchini, Jonathan, Strachan, David P., Tobin, Martin D., Hall, Ian P.
Publikováno v:
The Lancet. Respiratory Medicine, 3(10), 769-781. ELSEVIER SCI LTD
Background\ud \ud Understanding the genetic basis of airflow obstruction and smoking behaviour is key to determining the pathophysiology of chronic obstructive pulmonary disease (COPD). We used UK Biobank data to study the genetic causes of smoking b
Autor:
Loth, Daan W., Gharib, Sina A., Wain, Louise V., Franceschini, Nora, Koch, Beate, Pottinger, Tess D., Smith, Albert Vernon, Duan, Qing, Oldmeadow, Chris, Lee, Mi Kyeong, Strachan, David P., James, Alan L., Huffman, Jennifer E., Vitart, Veronique, Ramasamy, Adaikalavan, Wareham, Nicholas J., Kaprio, Jaakko, Wang, Xin-Qun, Trochet, Holly, Flexeder, Claudia, Albrecht, Eva, Lopez, Lorna M., de Jong, Kim, Thyagarajan, Bharat, Alves, Alexessander Couto, Enroth, Stefan, Omenaas, Ernst, Joshi, Peter K., Fall, Tove, Launer, Lenore J., Loehr, Laura R., Fornage, Myriam, Li, Guo, Wilk, Jemma B., Tang, Wenbo, Manichaikul, Ani, Lahousse, Lies, Harris, Tamara B., North, Kari E., Rudnicka, Alicja R., Hui, Jennie, Gu, Xiangjun, Lumley, Thomas, Wright, Alan F., Hastie, Nicholas D., Campbell, Susan, Kumar, Rajesh, Pin, Isabelle, Scott, Robert A., Surakka, Ida, Liu, Yongmei, Holliday, Elizabeth G., Schulz, Holger, Heinrich, Joachim, Davies, Gail, Vonk, Judith M., Wojczynski, Mary, Pouta, Anneli, Wild, Sarah H., Ingelsson, Erik, Rivadeneira, Fernando, Hysi, Pirro G., Eiriksdottir, Gudny, Morrison, Alanna C., Rotter, Jerome I., Gao, Wei, Postma, Dirkje S., White, Wendy B., Rich, Stephen S., Hofman, Albert, Aspelund, Thor, Couper, David, Smith, Lewis J., Psaty, Bruce M., Lohman, Kurt, Burchard, Esteban G., Garcia, Melissa, Joubert, Bonnie R., McArdle, Wendy L., Musk, A Bill, Hansel, Nadia, Heckbert, Susan R., Zgaga, Lina, van Meurs, Joyce B.J., Navarro, Pau, Rudan, Igor, Oh, Yeon-Mok, Redline, Susan, Jarvis, Deborah L., Zhao, Jing Hua, Rantanen, Taina, O'Connor, George T., Ripatti, Samuli, Scott, Rodney J., Karrasch, Stefan, Grallert, Harald, Gaddis, Nathan C., Starr, John M., Wijmenga, Cisca, Minster, Ryan L., Lederer, David J., Pekkanen, Juha, Gyllensten, Ulf, Campbell, Harry, Morris, Andrew P., Hammond, Christopher J., Burkart, Kristin M, Beilby, John, Kritchevsky, Stephen B., Gudnason, Vilmundur, Hancock, Dana B., Williams, O Dale, Polasek, Ozren, Zemunik, Tatijana, Kolcic, Ivana, Petrini, Marcy F., Wjst, Matthias, Kim, Woo Jin, Porteous, David J., Smith, Blair H., Viljanen, Anne, Attia, John R., Sayers, Ian, Hampel, Regina, Gieger, Christian, Deary, Ian J, Boezen, H. Marike, Newman, Anne, Jarvelin, Marjo-Riitta, Wilson, James F, Lind, Lars, Stricker, Bruno H., Teumer, Alexander, Spector, Timothy D., Peters, Marjolein J., Lange, Leslie A., Barr, R. Graham, Bracke, Ken R., Verhamme, Fien M., Sung, Joohon, Hiemstra, Pieter S., Cassano, Patricia A., Sood, Akshay, Hayward, Caroline, Hall, Ian P., Brusselle, Guy G., Tobin, Martin D., London, Stephanie J.
Forced vital capacity (FVC), a spirometric measure of pulmonary function, reflects lung volume and is used to diagnose and monitor lung diseases. We performed genome-wide association study meta-analysis of FVC in 52,253 individuals from 26 studies an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::53e48f87b6741dab7b20ec2463d628dc
Autor:
Loth, Daan W, Artigas, María Soler, Gharib, Sina A, Wain, Louise V, Franceschini, Nora, Koch, Beate, Pottinger, Tess D, Smith, Albert Vernon, Duan, Qing, Oldmeadow, Chris, Lee, Mi Kyeong, Strachan, David P, James, Alan L, Huffman, Jennifer E, Vitart, Veronique, Ramasamy, Adaikalavan, Wareham, Nicholas J, Kaprio, Jaakko, Wang, Xin-Qun, Trochet, Holly, Kähönen, Mika, Flexeder, Claudia, Albrecht, Eva, Lopez, Lorna M, Jong, Kim de, Rantanen, Taina
Forced vital capacity (FVC), a spirometric measure of pulmonary function, reflects lung volume and is used to diagnose and monitor lung diseases. We performed genome-wide association study meta-analysis of FVC in 52,253 individuals from 26 studies an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1222::bce48756d605c30926cdd2b0ba3321a4
http://urn.fi/URN:NBN:fi:jyu-201909184198
http://urn.fi/URN:NBN:fi:jyu-201909184198
Autor:
Repapi, Emmanouela, Sayers, Ian, Wain, Louise V, Burton, Paul R, Johnson, Toby, Obeidat, Ma'en, Zhao, Jing Hua, Ramasamy, Adaikalavan, Zhai, Guangju, Vitart, Veronique, Huffman, Jennifer E, Igl, Wilmar, Albrecht, Eva, Deloukas, Panos, Henderson, John, Granell, Raquel, McArdle, Wendy L, Rudnicka, Alicja R, Barroso, Inês, Loos, Ruth J F, Wareham, Nicholas J, Mustelin, Linda, Rantanen, Taina, Surakka, Ida, Imboden, Medea, H Wichmann, Erich, Grković, Ivica, Janković, Stipan, Zgaga, Lina, Hartikainen, Anna-Liisa, Peltonen, Leena, Gyllensten, Ulf, Johansson, Åsa, Zaboli, Ghazal, Campbell, Harry, Wild, Sarah H, Wilson, James F, Glaser, Sven, Homuth, Georg, Völzke, Henry, Mangino, Massimo, Soranzo, Nicole, Spector, Tim D, Polašek, Ozren, Rudan, Igor, Wright, Alan F, Heliövaara, Markku, Ripati, Samuli, Pouta, Anneli, Naluai, Åsa Torinsson, Olin, Anna-Carin, Torén, Kjell, Cooper, Matthew N, James, Alan L, Palmer, Lyle J, Hingorani, Aroon D, Wannamethee, S Goya, Whincup, Peter H, Davey Smith, George, Ebrahim, Shah, McKeever, Tricia M, Pavord, Ian D, MacLeod, Andrew K, Morris, Andrew D, Porteous, David J, Cooper, Cyrus, Dennison, Elaine, Shaheen, Seif, Karrasch, Stefan, Schnabel, Eva, Schulz, Holger, Grallert, Harald, Bouatia-Naji, Nabila, Delplanque, Jérôme, Froguel, Philippe, Blakey, John D, Britton, John R, Morris, Richard W, Holloway, John W, Lawlor, Debbie A, Hui, Jennie, Nyberg, Fredrik, Jarvelin, Marjo-Riitta, Jackson, Cathy, Kähönen, Mika, Kaprio, Jaakko, Probst-Hensch, Nicole M, Koch, Beate, Hayward, Caroline, Evans, David M, Elliot, Paul, Strachan, David P, Hall, Ian P, Tobin, Martin D
Pulmonary function measures are heritable traits that predict morbidity and mortality and define chronic obstructive pulmonary disease (COPD). We tested genome-wide association with forced expiratory volume in 1 s (FEV1) and the ratio of FEV1 to forc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::a11762d70bb988dd4f619a3a6e2d76a2
https://www.bib.irb.hr/438789
https://www.bib.irb.hr/438789