Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Lorcan McGarvey"'
Autor:
Liam G Heaney, Stephen J. Fowler, Lorcan McGarvey, Rekha Chaudhuri, Ian D. Pavord, Peter Bradding, Tsc Hinks, Adel H. Mansur, Rahul Shrimanker, Simon Couillard
Publikováno v:
New insights into airways disease.
Rationale Patients with severe asthma, raised fractional exhaled nitric oxide (FeNO) and high blood eosinophil (Eos) counts are at increased risk of asthma attacks. Objective To investigate this relationship by correlating FeNO and blood Eos to infla
Autor:
Jørgen Vestbo, Augusta Beech, G. Choudhury, Jadwiga A. Wedzicha, A. Deans, Charlotte E. Bolton, K.P. Yip, Andras Bikov, Gavin C. Donaldson, Andrew I. Ritchie, B. King, F. McLean, Alex R Jenkins, E. Sapey, P.M.A. Calverley, Lorcan McGarvey
Publikováno v:
International Conference of the American-Thoracic-Society (ATS)
INTRODUCTION: Public health measures to reduce the transmission of COVID-19 have required various changes in life-style, including loss or risk to employment and social isolation. We wished to assess how these measured effected 30-45 year old smokers
Autor:
Lex W. Doyle, Petteri Hovi, Kari Anne I. Evensen, Lorcan McGarvey, Pieta Nasanen-Gilmore, Sigurd Steinshamn, Indra Narang, Elianne J.L.E. Vrijlandt, Thomas Halvorsen, Sture Andersson, Andrew Bush, Hege Clemm, Jeanie L.Y. Cheong, Katherine J Lee, Aisling Gough, Eero Kajantie, Maria Vollsæter
Publikováno v:
The Lancet Respiratory Medicine
The Lancet. Respiratory Medicine, 7(8), 677-686. ELSEVIER SCI LTD
Doyle, L W, Andersson, S, Bush, A, LY Cheong, J, Clemm, H, Evensen, K A I, Gough, A, Halvorson, T, Hovi, P, Kajantie, E, Lee, K J, McGarvey, L, Narang, I, Näsänen-Gilmore, P, Steinshamn, S, Vollsaeter, M & Vrijlandt, E JLE 2019, ' Expiratory airflow in late adolescence and early adulthood in individuals born very preterm or with very low birthweight compared with controls born at term or with normal birthweight: a meta-analysis of individual participant data ', The Lancet Respiratory Medicine, vol. 7, no. 8, pp. 677 . https://doi.org/10.1016/S2213-2600(18)30530-7
The Lancet. Respiratory Medicine, 7(8), 677-686. ELSEVIER SCI LTD
Doyle, L W, Andersson, S, Bush, A, LY Cheong, J, Clemm, H, Evensen, K A I, Gough, A, Halvorson, T, Hovi, P, Kajantie, E, Lee, K J, McGarvey, L, Narang, I, Näsänen-Gilmore, P, Steinshamn, S, Vollsaeter, M & Vrijlandt, E JLE 2019, ' Expiratory airflow in late adolescence and early adulthood in individuals born very preterm or with very low birthweight compared with controls born at term or with normal birthweight: a meta-analysis of individual participant data ', The Lancet Respiratory Medicine, vol. 7, no. 8, pp. 677 . https://doi.org/10.1016/S2213-2600(18)30530-7
Background Maximal expiratory airflow peaks early in the third decade of life, then gradually declines with age. The pattern of airflow through adulthood for individuals born very preterm (at 2499 g) or at term. Methods We did a meta-analysis of indi
Autor:
John C. Lockhart, Zhixuan Yang, Fionnuala Lundy, Gerard P. Sergeant, Emma L. Carroll, James Reihill, Lorraine Martin, Lorcan McGarvey
Publikováno v:
The FASEB Journal. 33
Exposure to cockroach can lead to allergic airway inflammation. Serine proteases in cockroach extract (CRE) have been demonstrated to affect airway epithelial cells via activation of PARs (protease...
Autor:
Peter H. Howarth, Lars H. Nordenmark, Michel Laviolette, Himanshu Parikh, Vibeke Backer, Tina Skjold, Salman Siddiqui, Ingrid Louise Titlestad, Ronald Olivenstein, Dave Singh, Læge Carl Nielsen, Richard J. Russell, Gene L. Colice, Martin Braddock, Millie Wang, Latifa Chachi, Christopher E. Brightling, Lorcan McGarvey, Rekha Chaudhuri, Charlotte Suppli Ulrik, David Cohen, Brian Leaker, J. Mark FitzGerald, Tim Harrison
Publikováno v:
Russell, R J, Chachi, L, FitzGerald, J M, Backer, V, Olivenstein, R, Titlestad, I L, Ulrik, C S, Harrison, T, Singh, D, Chaudhuri, R, Leaker, B, McGarvey, L, Siddiqui, S, Wang, M, Braddock, M, Nordenmark, L H, Cohen, D, Parikh, H, Colice, G, Brightling, C E, Laviolette, M, Skjold, T, Nielsen, L C & Howarth, P 2018, ' Effect of tralokinumab, an interleukin-13 neutralising monoclonal antibody, on eosinophilic airway inflammation in uncontrolled moderate-to-severe asthma (MESOS) : a multicentre, double-blind, randomised, placebo-controlled phase 2 trial ', The Lancet Respiratory Medicine, vol. 6, no. 7, pp. 499-510 . https://doi.org/10.1016/S2213-2600(18)30201-7
Summary Background The role of interleukin 13 in airway inflammation and remodelling in asthma is unclear. Tralokinumab is a human monoclonal antibody that neutralises interleukin 13. We aimed to evaluate whether tralokinumab would have an effect on
Autor:
Jörgen Syk, Adrian Chan, Daryl Freeman, Elizabeth Gardener, Sen Yang, Martina Stagno d'Alcontres, Priyanka Raju Konduru, Kevin Gruffydd-Jones, Tze Lee Tan, Dermot Ryan, Therese Sophie Lapperre, Marcus Ngantcha, Lorcan McGarvey, David Price, Clifford Godley, Ngiap Chuan Tan, Mike Thomas, Ken Ohta, Roland Buhl
Publikováno v:
Price, D, Buhl, R, Chan, A, Freeman, D, Gardener, E, Goodley, C, Gruffydd-Jones, K, McGarvey, L, Ohta, K, Ryan, D, Syk, J, Chuan Tan, N, Tan, T, Thomas, M, Yang, S, Raju Konduru, P, Ngantcha, M, Stagno d’Alcontres, M & Lapperre, T 2018, ' Fractional exhaled nitric oxide as a predictor of response to inhaled corticosteroids in patients with non-specific respiratory symptoms and insignificant bronchodilator reversibility: a randomised controlled trial ', The Lancet Respiratory Medicine, vol. 6, no. 1, pp. 29-39 . https://doi.org/10.1016/S2213-2600(17)30424-1
The lancet respiratory medicine
The lancet respiratory medicine
Chronic non-specific respiratory symptoms are difficult to manage. This trial aimed to evaluate the association between baseline fractional exhaled nitric oxide (FeNO) and the response to inhaled corticosteroids in patients with non-specific respirat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::058962dac52ea4a8e9a48d4f9eca02f7
https://pure.qub.ac.uk/en/publications/fractional-exhaled-nitric-oxide-as-a-predictor-of-response-to-inhaled-corticosteroids-in-patients-with-nonspecific-respiratory-symptoms-and-insignificant-bronchodilator-reversibility-a-randomised-controlled-trial(083fb1da-b0f1-40f2-81f2-c3d4bb0788db).html
https://pure.qub.ac.uk/en/publications/fractional-exhaled-nitric-oxide-as-a-predictor-of-response-to-inhaled-corticosteroids-in-patients-with-nonspecific-respiratory-symptoms-and-insignificant-bronchodilator-reversibility-a-randomised-controlled-trial(083fb1da-b0f1-40f2-81f2-c3d4bb0788db).html
Autor:
Mike Thomas, Clifford Godley, Tze Lee Tan, David Price, Ken Ohta, Roland Buhl, Therese Sophie Lapperre, Lorcan McGarvey, Dermot Ryan, Anne Copland, Jörgen Syk, Kevin Gruffydd-Jones, Ngiap Chuan Tan, Adrian Chan, Lisa Law, Daryl Freeman
Publikováno v:
General Practice and Primary Care.
Background: Fractional exhaled nitric oxide (FeNO) can predict treatment response in asthma, but little is known of its utility in patients with non-specific respiratory symptoms (NSRS). Aims and objectives: To evaluate the association between baseli
Publikováno v:
Pulmonary Pharmacology & Therapeutics. 33:52-56
Respiratory viral infections are a common cause of acute coughing, an irritating symptom for the patient and an important mechanism of transmission for the virus. Although poorly described, the inflammatory consequences of infection likely induce cou
Autor:
Alyn H. Morice, Ian D. Pavord, Lorcan McGarvey, Bernard Higgins, Surinder S. Birring, Kian Fan Chung
© Journal of Thoracic Disease. Background: To investigate the effect of BC1036 on health-related quality of life (QOL) in subjects with persistent cough. The secondary objective was to investigate the effect of BC1036 on subjective cough severity. M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8d990f685ff3509dba9e9b672317013
http://hdl.handle.net/10044/1/53776
http://hdl.handle.net/10044/1/53776
Autor:
Kristina Bieksiene, Ahmad Kantar, Peter V. Dicpinigaitis, Jaclyn A. Smith, Maria G. Belvisi, Kian Fan Chung, Adalberto Pacheco, Lorcan McGarvey, Alyn H. Morice, Roberto W. Dal Negro, Eva Millqvist, Surinder S. Birring, Raimundas Sakalauskas
Publikováno v:
European Respiratory Journal. 44:1132-1148
In 2011, a European Respiratory Society Task Force embarked on a process to determine the position and clinical relevance of the cough hypersensitivity syndrome, a disorder characterised by troublesome coughing often triggered by low levels of therma