Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Huihuang Yan"'
Autor:
Huihuang Yan, Jeanette E. Eckel-Passow, Thai H. Ho, Matthew L. Kosel, Bradley C. Leibovich, Alexander S. Parker, Paul A. Decker, Robert B. Jenkins, Daniel J. Serie, Brian A. Costello
Publikováno v:
BMC Urology, Vol 20, Iss 1, Pp 1-9 (2020)
BMC Urology
BMC Urology
Background The four most commonly-mutated genes in clear cell renal cell carcinoma (ccRCC) tumors are BAP1, PBRM1, SETD2 and VHL. And, there are currently 14 known RCC germline variants that have been reproducibly shown to be associated with RCC risk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5283615d93dd4d961d9e915d17adcd3
https://doi.org/10.21203/rs.3.rs-48012/v3
https://doi.org/10.21203/rs.3.rs-48012/v3
Autor:
Andrew J. Haak, Huihuang Yan, Zhenqing Ye, Giovanni Ligresti, Daniel J. Tschumperlin, Nunzia Caporarello, Kyoung Moo Choi, Xaralabos Varelas, Tamas Ordog, Dakota L. Jones
Publikováno v:
J Cell Sci
Tissue fibrosis is a chronic disease driven by persistent fibroblast activation that has recently been linked to epigenetic modifications. Here, we screened a small library of epigenetic small-molecule modulators to identify compounds capable of inhi
Autor:
Susan L. Slager, Shuxia Peng, Michael T Kalmbach, Shulan Tian, Huihuang Yan, Krutika S. Gaonkar, Aditya Bhagwate, Wei Ding, Jeanette E. Eckel-Passow
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 4, p e0214723 (2019)
PLoS ONE, Vol 14, Iss 4, p e0214723 (2019)
Chromatin immunoprecipitation and sequencing (ChIP-seq) has been widely used to map DNA-binding proteins, histone proteins and their modifications. ChIP-seq data contains redundant reads termed duplicates, referring to those mapping to the same genom
Publikováno v:
BMC Genomics
Background Current variant discovery methods often start with the mapping of short reads to a reference genome; yet, their performance deteriorates in genomic regions where the reads are highly divergent from the reference sequence. This is particula
Autor:
Melissa L. Stanton, Rafael Nunez Nateras, Raoul Tibes, Richard W. Joseph, Alan H. Bryce, Jin Park, Thai H. Ho, Estrella M. Carballido, Erik P. Castle, William W. Wong, Alexander S. Parker, Jeong Heon Lee, Chad R. Borges, Huihuang Yan, Sally Jensen, Mark A. Todd, Mia D. Champion
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132831 (2015)
PLoS ONE
PLoS ONE
To address the need to study frozen clinical specimens using next-generation RNA, DNA, chromatin immunoprecipitation (ChIP) sequencing and protein analyses, we developed a biobank work flow to prospectively collect biospecimens from patients with ren
Autor:
Huihuang Yan, Sunduz Keles, Kun Liang, Patricia J. Kiley, Robert Landick, Irene M. Ong, Kevin S. Myers, Dongjun Chung, Frances Tran
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 9, Iss 6, p e1003565 (2013)
PLoS Genetics, Vol 9, Iss 6, p e1003565 (2013)
FNR is a well-studied global regulator of anaerobiosis, which is widely conserved across bacteria. Despite the importance of FNR and anaerobiosis in microbial lifestyles, the factors that influence its function on a genome-wide scale are poorly under
Publikováno v:
Genetics. 157(1)
We previously isolated a complete set of primary trisomics along with many other aneuploids from triploid plants derived from an indica rice variety “Zhongxian 3037.” About 30,000 progeny from these trisomic and aneuploid plants were grown each y
Autor:
Huihuang Yan, Jamie Jett, Jiming Jiang, Paul B. Talbert, Steven Henikoff, Hye-Ran Lee, Feng Chen
Publikováno v:
PLoS Biology, Vol 6, Iss 11, p e286 (2008)
PLoS Biology
PLoS Biology
Centromeres are sites for assembly of the chromosomal structures that mediate faithful segregation at mitosis and meiosis. Plant and animal centromeres are typically located in megabase-sized arrays of tandem satellite repeats, making their precise m
Publikováno v:
BMC Bioinformatics
Background GATK Best Practices workflows are widely used in large-scale sequencing projects and recommend post-alignment processing before variant calling. Two key post-processing steps include the computationally intensive local realignment around k