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Open chromatin profiling identifies AP1 as a transcriptional regulator in oesophageal adenocarcinoma
Autor:
Britton, Edward, Rogerson, Connor, Mehta, Shaveta, Li, Yaoyong, Li, Xiaodun, Fitzgerald, Rebecca C., Ang, Yeng S., Sharrocks, Andrew D.
Publikováno v:
PLoS Genetics
Oesophageal adenocarcinoma (OAC) is one of the ten most prevalent forms of cancer and is showing a rapid increase in incidence and yet exhibits poor survival rates. Compared to many other common cancers, the molecular changes that occur in this disea