Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jennifer L. Short"'
Publikováno v:
European Journal of Pharmacology. 592:151-157
Prostatic A 2A adenosine receptors mediate varied effects. This study aimed to test whether genetic disruption of this receptor affects prostate contractility. Prostates taken from mice which were homozygous (A 2A R−/−) and heterozygous (A 2A R+/
Publikováno v:
Neuropsychopharmacology. 34:844-856
The adenosine A(2A) receptor is specifically enriched in the medium spiny neurons that make up the 'indirect' output pathway from the ventral striatum, a structure known to have a crucial, integrative role in processes such as reward, motivation, and
Publikováno v:
Neuropsychopharmacology. 31:525-534
Here we report the development of D1A2A receptor knockout mice to investigate whether interactions between dopamine D1 and adenosine A2A receptors participate in reward-related behavior. The combined deletion of D1 and A2A receptors resulted in mice
Publikováno v:
Brain Research. 877:160-169
The present study was designed to assess whether adenosine A(2a) receptor knockout mice exhibit altered purine utilisation in brain nuclei. Specifically, the properties of adenosine transporters and adenosine A(1) receptors were characterised in brai
Publikováno v:
Neuroscience Letters. 291:97-100
Adenosine A(2a) receptor knockout mice (A(2a)R k/o) have been characterised as hypertensive, aggressive, anxious and hypoalgesic [12]. Thus, the present study was designed to investigate markers of glutamatergic transmission in specific brain nuclei
Publikováno v:
Journal of cardiovascular pharmacology. 56(4)
Recent reports have shown that adenosine A 1 receptor-mediated cardioprotection requires concomitant A 2 receptor activation, but no study thus far has shown that this phenomenon occurs using A, agonists at reperfusion. Thus, we compared adenosine A
Autor:
Robyn M, Brown, Jennifer L, Short
Publikováno v:
The Journal of pharmacy and pharmacology. 60(11)
The specific events between initial presumably manageable drug intake and the development of a drug-addicted state are not yet known. Drugs of abuse have varying mechanisms of action that create a complex pattern of behaviour related to drug consumpt
Publikováno v:
The International Journal of Neuropsychopharmacology. 11
Adenosine and glutamate have been implicated as mediators involved in the self-administration of alcohol. In the present study we sought to determine whether adenosine receptors could interact with metabotropic glutamate receptors to regulate operant
Publikováno v:
Neuroscience
Neuroscience, Elsevier-International Brain Research Organization, 2006, 139 (2), pp.661-70. ⟨10.1016/j.neuroscience.2005.12.052⟩
Neuroscience, Elsevier-International Brain Research Organization, 2006, 139 (2), pp.661-70. ⟨10.1016/j.neuroscience.2005.12.052⟩
International audience; Dopamine and adenosine receptors are known to share a considerable overlap in their regional distribution, being especially rich in the basal ganglia. Dopamine and adenosine receptors have been demonstrated to exhibit a parall
Publikováno v:
Behavioural brain research. 143(2)
Adenosine and dopamine receptors interact in the CNS to modulate behaviour, including sensorimotor gating. Prepulse inhibition (PPI) has been suggested to be an operational measure of sensorimotor gating. PPI and startle habituation are disrupted in