Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Marie Makhlina"'
Autor:
Barry Koplowitz, Wei H. Yang, Robert Jordan, Keith Barnett, John Dodd, Luana Pesco Koplowitz, Marie Makhlina, Carl Spana
Publikováno v:
Drugs in R&D
Background and Objective PL8177 is a selective melanocortin 1 receptor agonist in development for the treatment of various immunologic and inflammatory conditions. Here we describe the pharmacokinetics of PL8177 after subcutaneous (sc) delivery in an
Publikováno v:
Frontiers in Pharmacology
Frontiers in Pharmacology, Vol 9 (2019)
Frontiers in Pharmacology, Vol 9 (2019)
Background: The melanocortin α-melanocyte stimulating hormone (α-MSH), an endogenous peptide with high affinity for the melanocortin 1 receptor (MC1r), has demonstrated prevention and reversal of intestinal and ocular inflammation in animal models.
Autor:
Jeffrey D. Edelson, Trevor J. Hallam, Douglas W. P. Hay, Kevin R. Silvester, Marie Makhlina, Cynthia J. Koziol-White, Jie Zhang, Shailesh S. Vengurlekar, Reynold A. Panettieri, Xiaomei Chen, Philip R. Cooper
The pharmacological and airways relaxant profiles of PL-3994 (Hept-cyclo(Cys-His-Phe-d-Ala-Gly-Arg-d-Nle-Asp-Arg-Ile-Ser-Cys)-Tyr-[Arg mimetic]-NH(2)), a novel natriuretic peptide receptor-A (NPR-A) agonist, were evaluated. PL-3994, a full agonist, h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98714b69a93690e447ad784559492f06
https://europepmc.org/articles/PMC4070431/
https://europepmc.org/articles/PMC4070431/